Antoine Molaro

Hello! Does anyone know of any 'seed' type grants/awards within Australia (or potentially abroad if they fund research internationally) that contribute toward research only costs (not salary)??

The Evolutionary Genomics of Meiotic Drive Abstract. Meiotic drivers are selfish genetic elements that gain transmission advantages by distorting equal, Mendelian segregation. For decades, biologist

Meiotic drive has long been considered as a genetic curiosity. Genomic "footprints" suggest otherwise.

Check out our new review doi.org/10.1093/molb..., a cross-taxa synthesis arguing that recurrent drive is a pervasive and underappreciated force in genome evolution.

This will be a great meeting on host adaptation to viral infections. Abstract deadline approaching!

🥁 #FragileNucleosome is back on Jan 28! We are very excited to host @au-ho-yu.bsky.social and @gcloner.bsky.social as our first speakers of 2026!
📋Please don't forget to register for our 2026 seminar series: us06web.zoom.us/webinar/regi...

📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...

Getting asked about how academics can continue to do science & inspire trainees even in the midst of a continued (escalated) assault on science, reason, truth, & human rights. I don’t have great answers.

I would love to hear from mentors about advice they’re giving to trainees/ colleagues.

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

🚨Application for the MPI-IE international PhD program is ongoing🚨
If you are interested in #epigenetics #genomics #cellbiology #devbio & more, apply before February 6th!
My lab will recruit a student to work on the contribution of #transposable elements in development and disease 🧬🦠

Epimutations: raw material for evolution? - The EMBO Journal Epigenetics is fundamental to cell differentiation as it enables cells with identical genomes to adopt distinct fates. Some epigenetic information can also be transmitted between generations, in a pro...

Need a bit of escapism? Not exactly Lord of the Rings, but in similar vein:
doi.org/10.1038/s443...

Fluorescence microscopy image of an ovarian follicle (light blue/magenta), with a bright central oocyte.

💥🥚 ANR-funded Assistant Engineer position open in our “Control & Dynamics of the Ovarian Cycle” group at IBDM Marseille 🇫🇷

Work on mouse lines + lab logistics + follicle culture/imaging 🔬

🗓️ Apply by 26 Jan: emploi.cnrs.fr/Offres/CDD/U...

Please share widely — especially with colleagues in France!

New work from @miyapan.bsky.social and our team, bringing ant, bee, and wasp labs together. @chuanxinyu.bsky.social shows that the ANTSR locus we discovered in ants has determined sex for 150+ My across bees and stinging wasps 🐜🐝, despite virtually no sequence conservation 😮 doi.org/10.1073/pnas...

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform Mammalian SWI/SNF chromatin remodeling complexes modulate DNA accessibility and gene expression; however, their genomic targeting mechanisms remain incompletely understood. Here, we identify SWIFT (SW...

🧬 @science.org A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform | Science www.science.org/doi/10.1126/... @ckadoch.bsky.social @danafarber.bsky.social @harvardmed.bsky.social @broadinstitute.org @hhmi-science.bsky.social 🔬 #chromatin #transcription #cancer 🧫

Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development - Nature Communications H3K4 methylation is required for defining active chromatin states in Xenopus embryos, ensuring faithful zygotic genome activation and successful embryonic development.

Love this paper from @evahoermanseder.bsky.social and team; great to see it out. This is definitely "epigenetics" by any definition, but I wonder if it's premarking for activation or protecting against stable silence (i.e, DNAme), similar to Dppa2/4 targets in mammals www.nature.com/articles/s41...

A human embryo implantation model from the @Rugg-Gunn Lab

*key for understanding the early extraembryonic-maternal interactions

Congrats to everyone involved! It’s been great to see this project develop. Huge credit to the @babrahaminst.bsky.social authors 🥂🍾

www.cell.com/cell/fulltex...

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

An integrated view of the structure and function of the human 4D nucleome - Nature The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitatin...

A major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists!

www.nature.com/articles/s41...

Application to speak in the Fragile Nucleosome series Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...

Do you have an exciting new chromatin/transcription story that you'd like to share with the #FN community?

Fill out this form to be considered for a talk in our Jan-June 2026 schedule! forms.gle/TBi38UgYxPAB...

Please repost and share!

If anyone has any ideas that they would like to work on in choanoflagellates or Nematostella (or both) then please reach out!

Insights into natural neocentromere evolution from a cattle T2T X chromosome. #CattleGenome #T2T #HaplotypeResolvedGenome #Centromeres #Genomics @natcomms.nature.com 🧪🧬 🖥️
www.nature.com/articles/s41...

Permanent Research Group Leader Position, Crete, Greece: Interested to assume long-term responsibilities for the Biodiversity Computing Group www.biocomp.gr I have set up in Crete? Apply now via apella.minedu.gov.gr/en/node/5998 (PDF also in English) - for questions email to stamatak@ics.forth.gr

Retroviral insertions contributed to the divergence of human and chimpanzee brains Over the past 5 to 7 million years, humans and chimpanzees have diverged in brain size, structural complexity, and cognitive abilities despite high conservation of protein-coding genes. Notably, the e...

New preprint from our lab: ‘Retroviral insertions contributed to the divergence of human and chimpanzee brains’. Very proud of this piece which took almost a decade to finish.

www.biorxiv.org/content/10.6...

Fantastic #EvoChromo25. Wonderful iteration, learned a lot - and loved the Nirenberg gold Luger nucleosome prize ! Humor sun and outstanding and thought-provoking science.

Took us a bit, but proud of this published version. We now examine the genetic interaction of phosphorylation with oligomerization and where bulk and phospho-Swi6 localize. Wonder if chromatin affinity tuning to enable Suv39 H3K9me3 spreading is a conserved mechanism ?

doi.org/10.1093/nar/...

Dynamic evolution of EZHIP, an inhibitor of the Polycomb Repressive Complex 2 in mammals The Polycomb Repressive Complex 2 (PRC2) is an ancient, conserved chromatin-interacting complex that controls gene expression, facilitating differentiation and cellular identity during development. It...

@pravrutharaman.bsky.social got super intrigued about EZHIP/CATACOMB, previously identified as a histone H3K27M mimic of PRC2. You can read about her efforts here: www.biorxiv.org/content/10.6... We hope these analyses will help spur more analyses in this very cool gene! 1/

Please help! We are looking for tissue-specific RNA-seq datasets or pubs with both male and female individual gene expression data, not pooled, from animal species. If you know of any relevant resources, please drop a link in the comments or send me a DM. Also, please help spread the word - thanks!

a man with a mustache says go ahead make your jokes mr. jokey ALT: a man with a mustache says go ahead make your jokes mr. jokey

JOKES

So long #EvoChromo2025! I encourage you to mark your calendars as soon as the next one is announced. Special congrats to the Nirenberg prize recipients - including our very own @germainekaram.bsky.social
Here is a picture of Germaine receiving her Golden Luger from the hands of Nick Irwin. #ProudPI

Have you ever wondered how new DNA methylation patterns are established?

Paradigm shift ahead! We discovered a new mode of DNA methylation targeting in plants that relies on transcription factors and sequence motifs rather than chromatin modifications to regulate the methylome. rdcu.be/eQ6L5
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Join our online seminar on December 16, 2025, at 16:00 UTC to celebrate the book release "The Paradox of the Organism". More info: https://internalconflictsstn.wordpress.com/ #conference

The Department of Genetics at the University of Cambridge is seeking a talented Postdoctoral Research Associate to work in the group of Dr Felipe Karam Teixeira (www.gen.cam.ac.uk/research-gro...)

➡️For Further details see the link www.cam.ac.uk/jobs/postdoc...