@antoinemolaro.bsky.social
Group Leader @GReD_Clermont Chargé de Recherche @INSERM Evolutionary biologist studying chromatin also drummer. Jazz and epistemology. he/his https://www.igred.fr/en/team/evolutionary-epigenomics-and-genetic-conflicts/
Interested in one of the top jobs in European biology?
@embo.org has opened a call for its next Director, to succeed Fiona Watt
Really spectacular opportunity! Spread the word...
www.embo.org/features/emb...
We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).
Hello World ! Today, we have been so lucky to host the one and only Emily Hodges @hodges-lab.bsky.social to hear about her research. So many idea, so much cool stuff. Thank you Emily for sharing your science with us @igred.fr !
#Friends #Science #DNAmethylation #watwat
Very happy to have contributed to this mastodon of a paper by Yinan @yinanwan.bsky.social. Whole-mount spatial transcriptomics in zebrafish y'all 🐟🧪
Check out this collaboration between Kellie Jurado’s lab and mine. We find that paternal immune activation reprograms the epididymis and, subsequently, small RNAs in sperm, which modulate post-fertilization embryonic gene expression and immunity in offspring in a sex-specific manner.
Cool paper, turning evolutionary theory on its head - gene conversion overcomes the cost of asexual reproduction…
Gene conversion empowers natural selection in a clonal fish species www.nature.com/articles/s41...
Our lab is hiring a postdoctoral researcher with expertise in bioinformatics, evolutionary genomics and single-cell data analyses, to explore the evolution of reproductive organs across fishes. We are located in Rennes, France (INRAE-LPGP). For more details: florentmuratwebpage.wordpress.com
Positive selection targeted primate genes that encode transposable element repressors academic.oup.com/gbe/article/...
Our work on bacterial Schlafens in phage defense is out today @natmicrobiol.nature.com!
Check out the final version here:
rdcu.be/e7Bmz
We are looking for postdocs and students to expand our team! Official postings are coming soon.
Please reach out if you're interested!
#phage #phagesky #microsky
🚨 Job Alert - Please share! 🙏
Interested in 3D gene regulation in development & evolution? 🤓🧬
💥 Our lab at @cabd-upo-csic.bsky.social is expanding!
We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome
👇 Details below
Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org
![Figure 6. Examples of NRL changes in biological systems. (A) Cell differentiation leads to NRL changes between different cell types, e.g. mouse dorsal root ganglia neurons (NRL ∼165 bp) versus cortical astrocytes (NRL ∼183 bp) [175]. Schematic cell shapes are adapted from an image created in BioRender (https://BioRender.com/89trj2t). (B) Paired normal versus tumour breast tissues show NRL shortening in cancer (figure adapted from [36] under the CC BY 4.0 licence (https://creativecommons.org/licenses/by/4.0/)). (C) Nucleosome positioning derived from cfDNA of human volunteers shows NRL increase with age (figure reprinted from [79] under the CC BY 4.0 licence (https://creativecommons.org/licenses/by/4.0/)).](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:7rjg5hcnnloxgwuvwi23aixu/bafkreihl7mkdtxojw23qoqxm7yt57frzc24mjjllszhbohbvb67ffguccy)
Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: academic.oup.com/nar/article/...
A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy!
@milena-bikova.bsky.social @chrsclrksn.bsky.social
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n
Online Now: Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains Online now:
🤩to see this behemoth of a story out !
Pushed by @nikobiota.bsky.social & the Amazing @embl.org AML Team (Tina, Michael, Paulina) and in Co. with the Best #science #family you can dream of!
This truck was #home, for weeks in a row & in my heart for a lifetime.
www.biorxiv.org/content/10.6...
EPIPLANT conference
🌱 You like plants and epigenetics?
Explore mechanisms of chromatin regulation & epigenetics in Nantes, France!
🎤 Great speakers + oral & poster slots from selected abstracts.
22-24 June 2026
Abstract submission deadline: 24 April 2026.
epiplant-2026.sciencesconf.org
*Recruiting new group leaders*
The @lmcb-ucl.bsky.social at University College London are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.
Predictors of protein evolution in the drosophilid immune system url: academic.oup.com/gbe/article/...
#Drosohila #Immunity #fly #Evolution #Geneturnover #AdaptiveEvolution #Predictors #OrthologousGeneFamilies
The first version of FigTree was released nearly 20 years ago and it is still widely used (including by me). But there are currently 85 issues on the GitHub repo (github.com/rambaut/figt...) and some of them I don’t really like the look of.
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).
A brief 🧵 (carried over from the old place)
Following on from this amazing CoB workshop, we wrote a perspective on constructionist approaches to crack the cis-regulatory code.
All credit to @carldeboer.bsky.social who drove this, and never gave up on this piece.
Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs
“We know the fraudsters are going to fraud. We’re gonna make it a little bit harder for them”. @elisabethbik.bsky.social @abalkina.bsky.social & other sleuths share tips for detecting dodgy papers. By @sjmelchor.bsky.social @nature.com 🧪 www.nature.com/articles/d41...
🚨 We’re happy to announce (finally!) the publication of METALoci, in collaboration with @dariloops.bsky.social and heroes: @jrotwitguez.bsky.social & @imotagom.bsky.social.
METALoci integrates #3DGenome and #Epigenetics data into a unified framework we believe is very useful!
Here 👉🏻 rdcu.be/e5sm2
In academic depts, ‘jobs’ for many folks increased manifold in the past 15 months with no pay increases. They talk to your trainees & junior colleagues and talk them off high ledges. They organize and fight for the greater good.
Find them. Celebrate them. Reward them.
Don’t take them for granted.
postdoc recruitment still open!
Happy to share our latest paper.
Our findings uncover a unique chromatin architecture and spatial chromosome arrangement in gonadal germ cells and document that alongside global DNA demethylation, the germline epigenetic reprogramming involves reorganisation of the 3D genome.
#mustread
So excited to share this manuscript led by the inimitable Cara Brand, who discovered that Topoisomerase II evolution causes hybrid female lethality in Drosophila.
Congrats to Cara, @nickbr0wn.bsky.social, Anirban, and
@buszczaklab.bsky.social!
www.biorxiv.org/content/10.6...
Our paper is now out in Nature:
“Ancient co-option of LTR retrotransposons as yeast centromeres”
www.nature.com/articles/s41...
A short thread on how retrotransposons helped give rise to yeast point centromeres.
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