Dancer_Finn 🐺♾️🧪 (Semi-Active)

Rocky Mountain Magpie 🖤💙

Meet the Rocky Mountain Magpie! A mischievous little troublemaker with a heart of gold. This bestie's got attitude, flair, and just the right amount of chaos

Available on the Plushie Dreadfuls store ⭐

Pikachupi 💕

HAPPY VALENTIMES FROM ELDRITCH DARLING!!💕👁💕 and reminder that we’re down to the final hours for the Ina Plush preorder!!

Open until the 13th!! :3c
💘💘💘

Hit the slopes! 🏔️

[ #art #commissions ]

Did you know wolf families are lead by strong females? As if there weren't already countless reasons to love wolves!🐺

Here’s to friendship, loyalty, and fierce female energy.🩷 #HappyGalentinesDay

YouTube video by GLITCH KNIGHTS OF GUINEVERE ANNOUNCEMENT

Knights of Guinevere officially has the greenlight, folks!

www.youtube.com/watch?v=3oC8...

YouTube video by GLITCH KNIGHTS OF GUINEVERE ANNOUNCEMENT

LET'S GOOOOOOOO

youtu.be/3oC8ta-7Rds

Mission Failed

It's his day...

#pokémon #art #fanart #pokemonfanart #pokemonart #heracross #ヘラクロスの日

in today's episode of "this is a bug but wouldn't it be funny if it were a feature":

follower go beeg

chuuli @poppydu.bsky.social as a magical girl

More Chuuli @poppydu.bsky.social magical girl

Gonna try and finally post here. Starting off with fanart for @poppydu.bsky.social

I was thinking of working on this a little bit more, but I honestly now think it’s fine how it is.

We spoke to @martigcummings.bsky.social at the the flag raising days after the Trump Administration removed the Pride flag from the Stonewall National Monument. 🏳️‍🌈 🏳️‍⚧️

See their full remarks here: www.instagram.com/p/DUsosIIDsxR/

This study shows great promise and is a really novel idea leveraging natural mechanisms of protection again DNA damage for the purpose of protecting healthy cells during radiation treatments for cancer. If developed for use in humans, researchers say this protein could also potentially be used to

want to protect the tumor itself from the effects of radiation. To make this treatment more feasible for potential use in humans, researchers plan to work on developing a version of the Dsup protein that would not provoke an immune response, as the original tardigrade protein likely would.

cancer patients would receive. In these mice, researchers saw a 50% REDUCTION in the amount of double-stranded DNA breaks caused by radiation! Researcher also discovered that the protective effect of the Dsup protein DID NOT spread beyond the injection site, which was important because they don’t

successfully deliver mRNA to cells grown in the lab, researchers then tested whether this approach could effectively protect tissue from radiation in a mouse model. Researchers injected the particles into either the cheek or the rectum several hours before giving a dose of radiation similar to what

That’s indeed what they saw! One of the strengths of their approach was that they used a messenger RNA, which just temporarily expresses the protein, so it was considered far safer than something like DNA, which may be incorporated into the cells’ genome. After showing that these particles could

best-suited for delivery to the colon, and another that was optimized to deliver mRNA to mouth tissue. Their thought process? By combining these two systems of polymers and lipids, they thought they MIGHT just be able to get the best of both worlds and get highly potent RNA delivery- AND guess what?

would generate large amounts of protein in the target tissues. They screened libraries of delivery particles containing both polymer and lipid components, which have been used separately to achieve efficient mRNA delivery. From these screens, they identified one polymer-lipid particle that was

messenger RNA encoding Dsup to patient tissues before radiation treatment. This mRNA would trigger cells to transiently express the protein, protecting DNA during the treatment. After a few hours, the mRNA and protein would disappear. For this to work, researchers needed a way to deliver mRNA that

damage. This protein plays a major role in tardigrades’ ability to survive radiation doses 2,000 to 3,000 TIMES HIGHER than what a human being can tolerate. When brainstorming ideas for novel ways to protect cancer patients from radiation, researchers wondered if they might be able to deliver

Tardigrades have been known to survive: • Low temperatures of 0.05 kelvins (-272.95 degrees Celsius or functional absolute zero) •High temperatures of 150 degrees Celsius •Pressures of 40,000 kilopascals •The burning ultraviolet radiation of space • Being shot from a high-speed gun (traveling at nearly 3,000 feet per second and the impact of 1.14 gigapascals of pressure) •Being stored in a freezer for 30 years

Putting their hardiness to one of the biggest tests, tardigrades have been shown to survive after exposure to outer space. In 2007, dehydrated tardigrades were taken into low Earth orbit as part of the FOTON-M3 mission. They were exposed to either the hard vacuum of outer space (and protected from UV radiation) or vacuum and solar UV radiation for 10 days straight. After their return to Earth, the water bears that were protected from UV were reanimated within 30 minutes of rehydration. Subsequent mortality was high, but many were able to produce viable embryos before they died. In 2017, researchers from Oxford and Harvard Universities decided to test how resilient different forms of life were to potential astrophysical events - things like asteroids, supernova blasts and gamma ray bursts. Of course, humans stood no chance. But who stuck around? Tardigrades. They found that these little organisms could survive in most cases, pointing to the potential for them to survive on Earth long after humans have been wiped out. In more recent experiments, researchers have tested whether the hardy little animals can survive violent impacts similar to those that might explain how life originated on Earth - or even how it could be sent to other planets. In April 2019, an Israeli spacecraft carrying thousands of tardigrade passengers crashed into the surface of the moon. At the time, there was a lot of speculation about whether the critters could have survived and if we'd accidentally repopulated this barren landscape. Why does this matter? Not only does it give us a clue as to how one of the prevailing theories behind the origin of life on Earth could hold true - panspermia - but it could also give us an insight into how life might be sent to other planets.

conditions. Scientists have even sent them into space, where they were shown to survive extreme dehydration and cosmic radiation. One key component of tardigrades’ defense systems is a unique damage suppressor protein called Dsup, which binds to DNA and helps protect it from radiation-induced

researchers have been working on developing new ways to prevent radiation damage. In this new study, they were inspired by the extraordinary survival ability of tardigrades. Found all over the world, usually in aquatic environments, these organisms are well known for their resilience to EXTREME

to prevent radiation damage in cancer patients. There are a handful of drugs that can be given to try to reduce the damage, and for prostate cancer patients, a hydrogel can be used to create a physical barrier between the prostate and the rectum during radiation treatment. For several years,

address was the fact that radiation can manifest as something as simple as mouth sores, which can limit the ability to eat because it’s so painful, to requiring hospitalization because people are suffering so terribly from the pain, weight loss, or bleeding. Currently, there are very few ways

of the head and neck, it can damage the mouth or throat, making it very painful to eat or drink. It is also commonly used for gastrointestinal cancers, which can lead to rectal bleeding. Many patients end up delaying treatments or stopping them altogether. Something researchers wanted to try and