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Paul Sample

@paulsample.bsky.social

Biology x AI and trying to find the calm in the storm.

1,490 Followers  |  677 Following  |  41 Posts  |  Joined: 12.09.2023  |  1.8319

Latest posts by paulsample.bsky.social on Bluesky

Today would be a great day for the AI research community to leave X for good. In your own self interest and for the public perception of AI, take a stand.

Unless you agree with using it as a misinformation and propaganda machine, I guess.

08.07.2025 22:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Introducing SciArena, a platform for benchmarking models across scientific literature tasks. Inspired by Chatbot Arena, SciArena applies a crowdsourced LLM evaluation approach to the scientific domain. ๐Ÿงต

01.07.2025 15:02 โ€” ๐Ÿ‘ 15    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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GitHub - anthropics/claude-code-sdk-python Contribute to anthropics/claude-code-sdk-python development by creating an account on GitHub.

Anthropic's Claude Code Python SDK just released? Currently sitting at 1 star!
github.com/anthropics/c...

12.06.2025 16:53 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

These are wonderfully weird.

22.05.2025 05:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Robin: A multi-agent system for automating scientific discovery

Robin: A multi-agent system for automating scientific discovery

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Robin: A multi-agent system for automating scientific discovery [new]
Automating scientific discovery via a multi-agent system that integrates literature search and data analysis to propose/validate hypotheses.

20.05.2025 02:32 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The learning objective is next token prediction, but to do that well the models have to learn a deeper representation of โ€œthe worldโ€. Compare the latest LLMs to a simple N gram model and tell me that theyโ€™re just โ€œnext wordโ€ predictors.

16.05.2025 17:53 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Text Shot: Now the biggest project with heat recovery technology anywhere in the world is underway just outside Helsinki. Microsoft Corp. is building a cluster of data centers that, when completed, should supply heating to 40% of Espoo, Finlandโ€™s second-largest city. Thatโ€™s about 100,000 homes. A local coal-fired heating plant has already shut as itโ€™s no longer needed.

More major Finnish data center projects using heat recovery have been announced in May and March; other examples are already running in Sweden.

Text Shot: Now the biggest project with heat recovery technology anywhere in the world is underway just outside Helsinki. Microsoft Corp. is building a cluster of data centers that, when completed, should supply heating to 40% of Espoo, Finlandโ€™s second-largest city. Thatโ€™s about 100,000 homes. A local coal-fired heating plant has already shut as itโ€™s no longer needed. More major Finnish data center projects using heat recovery have been announced in May and March; other examples are already running in Sweden.

Power-Hungry Data Centers Are Warming Homes in the Nordics https://bloom.bg/4jYABDI #AI #DataCenters #climate

14.05.2025 20:00 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

WhyTF would people use Grok when they do things like this? Not to mention the pollution theyโ€™re producing in Memphis.

14.05.2025 18:44 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

There is no bigger turn off to reading a paper than seeing the words โ€œis all you needโ€ in the title.

13.05.2025 14:46 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
itter.sh - Social Media via SSH itter.sh: Ironic, text-only, SSH-based social networking for terminal lovers. No browser, no js, just eets.

Finally, the Twitter/X killer. Nothing quite as satisfying as operating in purely in a terminal.
www.itter.sh

09.05.2025 23:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

I always look forward to FutureHouse releases. I had to do a little digging for API information so here it is for those who are interested.
futurehouse.gitbook.io/futurehouse-...

02.05.2025 22:52 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I knew he would do this. I wrote a whole article about how he would do this. I am not surprised heโ€™s undermining vaccination. I know heโ€™s an anti-vaxxer & a predatory crank.

And yetโ€ฆyou have got to be fucking kidding me. Heโ€™s promoting infant mortality.

30.04.2025 04:54 โ€” ๐Ÿ‘ 650    ๐Ÿ” 196    ๐Ÿ’ฌ 18    ๐Ÿ“Œ 7

We have to be reaching the sycophancy floor soon.. right?

29.04.2025 23:07 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I had no idea. Very useful โ€” thanks for sharing.

29.04.2025 18:49 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Iโ€™m curious about what your thoughts are on the odds of Trump et al putting a finger on the scale if Tesla shares tank. And ultimately, what could they reasonably do to give it some juice.

19.04.2025 01:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling

Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling

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Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling [new]
Atlas maps 50 cancer lines' trancriptomic response to 1.1k mols, aiding AI modeling.

24.02.2025 20:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Genome modeling and design across all domains of life with Evo 2

Genome modeling and design across all domains of life with Evo 2

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Genome modeling and design across all domains of life with Evo 2 [new]
Evo 2:
Learns genomic features across life's domains from DNA alone and generates coherent, controllable genome sequences at scale.

22.02.2025 03:07 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Trump Live Updates: Layoffs, Ukraine War and Deportation News

"Most baffling to many were the firings of hundreds whose jobs were not funded by taxpayers. Their positions were financed through congressionally approved agreements that routed fees from the drug, medical device and tobacco industries to the agency."
๐Ÿคก
www.nytimes.com/live/2025/02...

21.02.2025 19:55 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The foundations of Americaโ€™s prosperity are being dismantled Federal scientists warn that Americans could feel the effects of the new administration's devastating cuts for decades to come

For decades, the US government has painstakingly kept American science #1 globallyโ€”and every facet of American life has improved because of it. The internet? Flu shot? Ozempic? All grew out of federally-funded research. Now all that's being dismantled. 1/ www.technologyreview.com/2025/02/21/1...

21.02.2025 13:00 โ€” ๐Ÿ‘ 3056    ๐Ÿ” 1534    ๐Ÿ’ฌ 80    ๐Ÿ“Œ 118

๐Ÿคฎ

16.02.2025 17:24 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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What is Internal Knowledge Search | Perplexity Help Center Internal Knowledge Search allows both Perplexity Pro and Enterprise Pro users to search across internal files alongside the web.

Has anyone tried this? Struggling to find an information retrieval system I like.
www.perplexity.ai/help-center/...

04.02.2025 04:30 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

www.openbioml.org has a discord.

02.02.2025 04:24 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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โ€ŽThe You You Are โ€ŽHealth, Mind & Body ยท 2025

Severance obsessives like myself may be interested to hear that the first 8 chapters of The You You Are by Dr. Ricken Lazlo Hale, PhD are now available for free as both text and an audiobook read by Ricken himself: books.apple.com/us/book/the-...

31.01.2025 18:17 โ€” ๐Ÿ‘ 13    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Avoidance is better for mental health but not for decision making in an increasingly complex and unpredictable world.

27.01.2025 18:31 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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R1+Sonnet set SOTA on aiderโ€™s polyglot benchmark R1+Sonnet has set a new SOTA on the aider polyglot benchmark. At 14X less cost compared to o1.

Aider reports that R1+Sonnet (R1 Thinking + Sonnet) set a new SOTA on the aider polyglot benchmark at 14X less cost compared to o1.

64% R1+Sonnet
62% o1
57% R1
52% Sonnet
48% DeepSeek V3

aider.chat/2025/01/24/r...

24.01.2025 17:46 โ€” ๐Ÿ‘ 41    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

I tried a few biology-related queries and was impressed with the results. Researchers should check this out.

21.01.2025 19:58 โ€” ๐Ÿ‘ 11    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

How have I been coding with Python for 10 years and just learned today that you can update the same line in a terminal using '\r' and end=''?
print(f"\rDownload progress: {percent}%", end='')
Thanks Claude.

18.01.2025 14:58 โ€” ๐Ÿ‘ 12    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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98% of microplastic particles (MP) in bottled water are smaller than 20 ฮผm, which are much more likely to get thru the GI tract to blood and organ tissue. Municipal tap water was higher in MP than 8 of 10 bottled water brands
journals.plos.org/water/articl...

16.01.2025 15:19 โ€” ๐Ÿ‘ 236    ๐Ÿ” 75    ๐Ÿ’ฌ 14    ๐Ÿ“Œ 8

@paulsample is following 20 prominent accounts