4/5
I think the framework has real potential for studying tumor heterogeneity, eco-evolutionary dynamics, and spatio-temporal interactions of heterogeneous agents in general.
3/5
To test it we look at an expanding population of cells that inherit their proliferation rate from their mother, with small random mutations. A traveling invasion wave forms - and it accelerates over time, because faster-growing mutants accumulate at the front.
2/5
Classical approaches force one cell per lattice site and cells belong to discrete types. We drop that constraint: each lattice point holds individual cells with their own properties: proliferation rate, phenotype, velocity, whatever you need to track.
1/5
New paper out in EPJ Special Topics with Josué Manik Nava-Sedeño (UNAM) & Andreas Deutsch (TU Dresden)! We built a cellular automaton framework for modeling genetically and phenotypically heterogeneous cell populations. 🧵
What truly made the experience special: new collaborations, inspiring discussions, and the energy of a community working at the intersection of math, biology & medicine.
Huge thanks to the organizers and everyone at @moffittnews.bsky.social!
Team Purple forever. 💜
At the IMO Workshop I joined Team Purple 💜.
We developed a concept integrating metabolic signatures, clinical data & mathematical modeling to guide personalized therapy in advanced ovarian cancer.
We finished as runner-up and received a $50k pilot grant to take the project forward!
Just wrapped up two inspiring weeks in Florida for #MathOnco25 and the IMO Workshop at @moffittnews.bsky.social - made possible by a generous travel award from the organizers.
Incredible science, great people, and a community that keeps pushing boundaries.
Thesis: tud.qucosa.de/api/qucosa%3...
- Latest paper on tumor heterogeneity: journals.plos.org/ploscompbiol...
- 15-min podcast-style summary of my dissertation: notebooklm.google.com/notebook/6e9...
Thanks to the Friedl & Deutsch groups and everyone involved!
Honoured to receive the 2024 Reinhart Heinrich Doctoral Thesis Award from @esmtbio.bsky.social
for my PhD on tumour evolution.
Looking forward to the #ECMTB2026 plenary in Graz.
Huge thanks to mentors, collaborators & students at
ZIH, CIDS and @tudresden.bsky.social.
#MathBio #Mathonco
People tell me nobody wants to look at climate curves anymore, yet here we are!!! Please enjoy our interactive journey through 485 million years of climate history and dive into the fascinating and important work of paleoclimate scientists.
🎁 www.zeit.de/wissen/umwel...
PS: If you're interested in a 15-min podcast-style summary of my work, have a look here (powered by NotebookLM by Google!):
notebooklm.google.com/notebook/6e9...
I conducted this work at the Center for Interdisciplinary Digital Sciences (CIDS) at @tudresden.bsky.social under the supervision of Andreas Deutsch. Thank you for all the support over the years!
I'm super happy and honored to be nominated for the Deutscher Studienpreis (German Thesis Award) by @koerber-ip.bsky.social for my PhD thesis on mathematical modeling of the impact of tumor heterogeneity on cancer evolution!
I'm looking forward to meeting the other nominees at the final in Berlin!
Today the Royal Society will meet to discuss “Fellows’ behaviour”. Without doubt the fellow they will primarily be discussing is Elon Musk.
The behaviour may range from his public dissemination of unfounded conspiracy theories to his attacks on the science
🧵
1/38
Can moving government jobs revitalize struggling regions? I explore this question in my new @nberpubs.bsky.social working paper, „The Potential of Public Employment Reallocation as a Place-Based Policy.“ 🧵(1/5)
#EconSky #PlaceBasedPolicies #RegionalDevelopment
Surveying the economics literature on capital relocations, purpose-built capitals, and public agency decentralization programs, synthesizing their effects on population, employment, and GDP, from Dimitria Freitas https://www.nber.org/papers/w33432
Thanks for the invitation, David! I really enjoyed my time visiting @moffittnews.bsky.social!
