Petter Brodin

Incidence and prevalence of autoimmune disease in the Swedish National Patient Register - European Journal of Epidemiology European Journal of Epidemiology - Standardized definitions of autoimmune disease (AD) are lacking. Therefore, we aim to propose a definition of AD for register-based research and estimate the...

New paper📢 - how many individuals are affected by an autoimmune disease. Together with epidemiology experts jonas Ludvigsson @ki.se we use 🇸🇪 population registry and find that 1/13 adults and 1/67 children are affected by autoimmunity: link.springer.com/article/10.1...

Expanding the scope of human immunology in the Journal of Human Immunity. New Editorial from Petter Brodin @petterbrodin.bsky.social, Megan Cooper @macattacklab.bsky.social, Jean-Laurent Casanova @casanovalab.bsky.social, and colleagues in the JHI Editorial team:

Tissue Regulatory T Cells FOXP3+ regulatory T cells (Tregs) have well-defined roles in limiting systemic immune responses against diverse stimuli. However, the observation that a subset of Tregs also enter nonlymphoid tissues,...

Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field

www.annualreviews.org/content/jour...

Paper alert 📢: What drives variation in humoral responses to viruses? collab with @etienne-patin.bsky.social @darraghduffy.bsky.social @lquintanamurci.bsky.social we show that for ~98k viral epitopes immunodominance vary by genetics, sex and origin: www.nature.com/articles/s41...

Expanding the scope of human immunology in the JHI. In this Editorial, @petterbrodin.bsky.social, @macattacklab.bsky.social, @casanovalab.bsky.social, alongside JHI's Associate, Consulting, as well as Society Editors, outline a broader scope for the journal. rupress.org/jhi/article/...

Available to read now via #OpenAccess
pubs.rsc.org/en/content/a...
@ki.se @petterbrodin.bsky.social

Gut health monitoring via intestinal barrier function screening using a transepidermal microneedle-based sensor
(2026)
Nicolas Maïno, Sihui Xuad, Petter Brodin and Onur Parlak

@petterbrodin.bsky.social

Three LMS researchers named among most influential in the world in 2025 Professors Wiebke Arlt, Petter Brodin and Boris Lenhard, who lead groups at the MRC Laboratory of Medical Sciences (LMS), have been included on the prestigious Highly Cited Researchers 2025 list.

🎉Congratulations to @wiebkearlt.bsky.social, @petterbrodin.bsky.social and @borislenhard.bsky.social for being named on Clarivate's list of Highly Cited Researchers for 2025!

This list celebrates influential academics whose work has made a profound impact on their field!

Women have supercharged immune systems and we now know why Being born with two X chromosomes brings a host of health benefits, and recognising this could lead to personalised medical treatments for men and women

Me and a few leading colleagues discuss female-specific immune systems in health and disease. By @starrevartan.bsky.social in @newscientist.com www.newscientist.com/article/2501...

Immunity debt: does it really exist? Some claim the rise in winter infections has been caused by the reduction of seasonal bugs during lockdowns. But experts are sceptical about these oversimplified explanations

Recap 2023 via @petterbrodin.bsky.social
@theguardian.com
www.theguardian.com/science/2023...
The term “immunity debt” was first introduced by French researchers in 2021. It refers to a population-wide effect rather than an individual-level one.

How the immune system develops in newborn babies | Knut and Alice Wallenberg Foundation Why are more and more people suffering from allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns. Wallenberg Scholar Petter Brodin has developed a ...

Why are more and more people suffering from #allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns @petterbrodin.bsky.social @ki.se has developed a technique to map #immunesystem development from a single drop of blood.
tinyurl.com/3j22dyw8

In new review @jhumimmunity.org, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...

Hehe, Thanks Grant!

The seven enigmas of #SARSCoV2: From the past to the future. New review from Evangelos Andreakos, Helen Su, Jean-Laurent Casanova (@casanovalab.bsky.social) and colleagues: rupress.org/jhi/article/...

#InbornErrorsOfImmunity #InfectiousDiseases #PopulationGenetics

Early Life Immune Development and Function   - IMMUNOLOGY2026™ Time: 8:00 - 11:30 AM Chairs: Chrysothemis C. Brown, Memorial Sloan Kettering Cancer Ctr., USA Petter Brodin, Imperial Col. London and Karolinska Inst., GBR, SWE

The American Association of Immunologists AAI meeting will be in Boston, April 15-19, 2026. Come join me and @chrysothemisbrown.bsky.social at this exciting Symposium on Early life immune development. Submit your abstracts by October 15th! immunology2026.aai.org/session/earl...

#Medsky🧪 #IDsky #immunosky #publichealth @petterbrodin.bsky.social , @casanovalab.bsky.social et al
To determine the underlying genetic causes & other modifying factors like sex hormones , interferon responses impacting restrained #Tcell responses to #SARSCoV2 & #viralpersistence in #LongCOVID.

Thx for highlighting @sun-in-winter12.bsky.social

Variation in the human immune system is largely driven by non-heritable influences - PubMed There is considerable heterogeneity in immunological parameters between individuals, but its sources are largely unknown. To assess the relative contribution of heritable versus non-heritable factors,...

Variation in the human immune system is largely driven by non-heritable influences
@petterbrodin.bsky.social P. Brodin et al. Cell. 2015.

Selective remodelling of the adipose niche in obesity and weight loss - Nature An atlas study of adipose tissue in people with obesity undergoing weight loss and their lean counterparts reveals that weight loss reduces cell senescence but cannot reverse all the metabolic problem...

Weight loss improves health but What happens to cells in the fat during weight loss? Intriguingly, immune cell numbers decrease but their activated states persist w chronic inflammatory potential. Beautiful work from neighbors @mrc-lms.bsky.social Will Scott et al www.nature.com/articles/s41...

New paper 📣! Pixelgen reports its incredible new Proximity Network Assay (PNA)->3D maps of 155 proteins in single cells by sequencing by barcoded antibodies and in situ rolling circle amplification yields >40,000 spatial nodes/cell: www.biorxiv.org/content/10.1...

Evaluating IL1RA‐Autoantibodies Across SARS‐CoV‐2‐Related Diseases Click on the article title to read more.

No evidence for neutralizing IL1RN autoantibodies in our cohorts of MIS-C, SARS-CoV2 pneumonia or vaccine-induced myocarditis. onlinelibrary.wiley.com/doi/10.1111/... Great work by Anish Behere in Nils Landegren lab, Uppsala university

Exciting new cell state model from @arcinstitute.org

Same!

Absolute pleasure to be teaching human systems immunology @efis-immunology.bsky.social summer school in beautiful Alghero, Sardinia.

"Children should be included in ongoing and future clinical trials for Long Covid

Age-related protections & regulations must be incorporated, including obtaining institutional review board/research ethics approval along with paediatric assent & parental

publications.ersnet.org/content/erj/...

Reminder to join us June 5/6 in Paris if you're interested in pediatric immunity and cancer development ! @institutcurie.bsky.social @gustaveroussy.fr @hopitalnecker.bsky.social @institutimagine.bsky.social

New in @jumimmunity.org:

Human #InbornErrorsOfImmunity: 2024 update on the classification from the @iuis-online.bsky.social Expert Committee: rupress.org/jhi/article/...

See also the accompanying diagnostic guide by Bousfiha et al.: rupress.org/jhi/article/...

Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee url:https://rupress.org/jhi/article/1/1/e20250003/277390/Human-inborn-errors-of-immunity-2024-update-on-the

Amazing study showing protective effect of herpes zoster vaccination against dementia with interesting sex differences @sexdiffimmunity.bsky.social
#vaccines work! #immunosky #medsky

Co-senior author from this study Prof Coziana Ciurtin will be talking alongside @petterbrodin.bsky.social in a RITA webinar on Sex Biases on Autoimmunity next Tuesday - should be a great discussion. Register 👇 #ImmunoSky #sexdifferences

register.gotowebinar.com/register/822...