Immunity debt: does it really exist?
Some claim the rise in winter infections has been caused by the reduction of seasonal bugs during lockdowns. But experts are sceptical about these oversimplified explanations
Recap 2023 via @petterbrodin.bsky.social
@theguardian.com
www.theguardian.com/science/2023...
The term βimmunity debtβ was first introduced by French researchers in 2021. It refers to a population-wide effect rather than an individual-level one.
09.11.2025 05:44 β π 3 π 1 π¬ 1 π 0
How the immune system develops in newborn babies | Knut and Alice Wallenberg Foundation
Why are more and more people suffering from allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns. Wallenberg Scholar Petter Brodin has developed a ...
Why are more and more people suffering from #allergies and autoimmune diseases? The answer may lie in the development of the immune system in newborns @petterbrodin.bsky.social @ki.se has developed a technique to map #immunesystem development from a single drop of blood.
tinyurl.com/3j22dyw8
15.10.2025 07:39 β π 8 π 3 π¬ 0 π 0
In new review @jhumimmunity.org, Andreakos et al. report the progress of the COVID Human Genetic Effort since its launch 5 years ago, with the aim to understand clinical variability, from resistance to severe outcomes, among individuals exposed to #SARSCoV2. rupress.org/jhi/article/...
24.10.2025 17:45 β π 1 π 1 π¬ 1 π 0
Hehe, Thanks Grant!
07.11.2025 22:00 β π 2 π 0 π¬ 0 π 0
The seven enigmas of #SARSCoV2: From the past to the future. New review from Evangelos Andreakos, Helen Su, Jean-Laurent Casanova (@casanovalab.bsky.social) and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #InfectiousDiseases #PopulationGenetics
31.10.2025 14:45 β π 5 π 4 π¬ 1 π 0
Early Life Immune Development and FunctionΒ Β - IMMUNOLOGY2026β’
Time: 8:00 - 11:30 AM Chairs: Chrysothemis C. Brown, Memorial Sloan Kettering Cancer Ctr., USA Petter Brodin, Imperial Col. London and Karolinska Inst., GBR, SWE
The American Association of Immunologists AAI meeting will be in Boston, April 15-19, 2026. Come join me and @chrysothemisbrown.bsky.social at this exciting Symposium on Early life immune development. Submit your abstracts by October 15th! immunology2026.aai.org/session/earl...
22.09.2025 15:23 β π 11 π 3 π¬ 0 π 0
#Medskyπ§ͺ #IDsky #immunosky #publichealth @petterbrodin.bsky.social , @casanovalab.bsky.social et al
To determine the underlying genetic causes & other modifying factors like sex hormones , interferon responses impacting restrained #Tcell responses to #SARSCoV2 & #viralpersistence in #LongCOVID.
10.09.2025 21:03 β π 7 π 3 π¬ 1 π 0
Thx for highlighting @sun-in-winter12.bsky.social
25.08.2025 19:48 β π 8 π 2 π¬ 2 π 0
Selective remodelling of the adipose niche in obesity and weight loss - Nature
An atlas study of adipose tissue in people with obesity undergoing weight loss and their lean counterparts reveals that weight loss reduces cell senescence but cannot reverse all the metabolic problem...
Weight loss improves health but What happens to cells in the fat during weight loss? Intriguingly, immune cell numbers decrease but their activated states persist w chronic inflammatory potential. Beautiful work from neighbors @mrc-lms.bsky.social Will Scott et al www.nature.com/articles/s41...
11.07.2025 10:06 β π 55 π 13 π¬ 1 π 0
New paper π£! Pixelgen reports its incredible new Proximity Network Assay (PNA)->3D maps of 155 proteins in single cells by sequencing by barcoded antibodies and in situ rolling circle amplification yields >40,000 spatial nodes/cell: www.biorxiv.org/content/10.1...
25.06.2025 13:45 β π 14 π 6 π¬ 1 π 0
Evaluating IL1RAβAutoantibodies Across SARSβCoVβ2βRelated Diseases
Click on the article title to read more.
No evidence for neutralizing IL1RN autoantibodies in our cohorts of MIS-C, SARS-CoV2 pneumonia or vaccine-induced myocarditis. onlinelibrary.wiley.com/doi/10.1111/... Great work by Anish Behere in Nils Landegren lab, Uppsala university
25.06.2025 06:59 β π 19 π 5 π¬ 0 π 2
Exciting new cell state model from @arcinstitute.org
23.06.2025 17:35 β π 1 π 0 π¬ 0 π 0
Same!
27.05.2025 16:50 β π 1 π 0 π¬ 0 π 0
Absolute pleasure to be teaching human systems immunology @efis-immunology.bsky.social summer school in beautiful Alghero, Sardinia.
27.05.2025 14:50 β π 28 π 4 π¬ 3 π 0
Header ERS Logo
Editorial | Viewpoint Open access
Equity in research: a global consensus statement on the urgency of including children in long COVID clinical trials
Lael M. Yonker Binita Kane Etheresia Pretorius David Putrino Sammie McFarland Petter Brodin Kanecia O. Zimmerman Daniel Munblit Peter C. Rowe Theo Vos David Warburton Terence Stephenson Danilo Buonsenso International Meeting on Long COVID in Children Consortium
"Children should be included in ongoing and future clinical trials for Long Covid
Age-related protections & regulations must be incorporated, including obtaining institutional review board/research ethics approval along with paediatric assent & parental
publications.ersnet.org/content/erj/...
23.05.2025 07:23 β π 32 π 12 π¬ 1 π 2
Reminder to join us June 5/6 in Paris if you're interested in pediatric immunity and cancer development ! @institutcurie.bsky.social @gustaveroussy.fr @hopitalnecker.bsky.social @institutimagine.bsky.social
30.04.2025 06:59 β π 10 π 2 π¬ 1 π 0
New in @jumimmunity.org:
Human #InbornErrorsOfImmunity: 2024 update on the classification from the @iuis-online.bsky.social Expert Committee: rupress.org/jhi/article/...
See also the accompanying diagnostic guide by Bousfiha et al.: rupress.org/jhi/article/...
23.04.2025 14:19 β π 4 π 2 π¬ 0 π 0
Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee url:https://rupress.org/jhi/article/1/1/e20250003/277390/Human-inborn-errors-of-immunity-2024-update-on-the
15.04.2025 18:01 β π 19 π 6 π¬ 0 π 0
Amazing study showing protective effect of herpes zoster vaccination against dementia with interesting sex differences @sexdiffimmunity.bsky.social
#vaccines work! #immunosky #medsky
03.04.2025 09:48 β π 12 π 4 π¬ 0 π 0
Co-senior author from this study Prof Coziana Ciurtin will be talking alongside @petterbrodin.bsky.social in a RITA webinar on Sex Biases on Autoimmunity next Tuesday - should be a great discussion. Register π #ImmunoSky #sexdifferences
register.gotowebinar.com/register/822...
28.03.2025 18:04 β π 22 π 9 π¬ 0 π 0
Image with Dr Binita Kane on the left and Dr Petter Brodin on the right. Text reads COVID AND THE IMMUNE SYSTEM. Dr. Binita Kane talks with Dr. Petter Brodin Garfield Weston Chair and Professor of Paediatric Immunology at Imperial College London
LIVE Wednesday 12th March 2025 18:00 GMT. THE LONG COVID CLINIC - WHAT YOU CAN DO You Tube @LCCWYCD. Also shown is the Long Covid Support logo.
π₯1/3. Next in the Fireside Chat series from The #LongCovid Clinic - What You CAN Do!
βCovid & the Immune Systemβ
ποΈ Wednesday 12th March 2025 at 6pm GMT
@binitakane.bsky.social & @helenoakleigh.bsky.social are joined by Consultant Immunologist @petterbrodin.bsky.social!
Link β¬οΈ
10.03.2025 18:52 β π 38 π 19 π¬ 2 π 0
Thx so much for highlighting!
10.03.2025 20:44 β π 4 π 1 π¬ 1 π 0
#Medskyπ§ͺ#oncosky #pedsky @petterbrodin.bsky.social et al . A systems-level analysis of immune responses in 191 children within a population-based cohort with diverse tumors & reveal that age & tumor type shape immune responses differently.#immunotherapies for childhood cancer.
09.03.2025 17:16 β π 3 π 1 π¬ 1 π 0
Symposium Paris Kids Cancer 2025 - Institut Curie
Find Symposium Paris Kids Cancer 2025. The Institut Curie is the leading center for research and the fight against cancer in France.
Interested in the relationship between the developing immune system and pediatric cancer ? Come join us for the first Paris Kids Cancer symposium June 5/6 institut-curie.org/symposium-pa... @institutcurie.bsky.social @aphp.bsky.social @gustaveroussy.fr @institutimagine.bsky.social
05.03.2025 10:48 β π 6 π 2 π¬ 2 π 1
Great #immuno speakers including @belkaidlab.bsky.social @petterbrodin.bsky.social @florentginhoux.bsky.social Arndt Borkhardt, Melanie Conrad, Sonia Garel, Sylvain Latour, Johnny Ludvigsson, Bernard Malissen, Mihai Netea, Anindita Roy and Chenqu Suo
05.03.2025 13:32 β π 2 π 1 π¬ 0 π 0
The February 2024 cover of Science Immunology depicts CRISPRβCas9βmediated repair of a dysfunctional cytotoxic T cell (red) from an individual with familial hemophagocytic lymphohistiocytosis (FHL), which allows it to secrete normal cytotoxic granules (pink) and effectively kill virally infected B cells (blue). (Credit: A. Fisher/Science Immunology)
To commemorate #RareDiseaseDay, here are some recent #Science #Immunology research papers that elucidate the immune mechanisms underlying certain rare human diseases and/or report new strategies to treat them! @science.org
28.02.2025 21:37 β π 44 π 14 π¬ 1 π 0
"Not all those who wander are lost" JR Tolkien
#Clinicalresearcher #DrugDevelopment
#Clinicaltrials & Registration
π§¬π¬πππ¦ 𧫠π
Melbourne π¦πΊ Oxford π¬π§& π΄σ §σ ’σ ³σ £σ ΄σ Ώ #MedSkyπ§ͺ
Professor of Immunology at Western University in London, Ontario, Canada; Past President of the Canadian Society for Immunology; Alumnus of NIH, Dalhousie University, and University of Manitoba
Physician-scientist in training. Neurologist. The Reich lab. NIH/NINDS. Interested in neuroscience, immunology, neurology, math and physics. Opinions are my own.
https://scholar.google.com/citations?hl=en&user=8HkrbWkAAAAJ&view_op=list_works
Scientist | Molecular Biologist | Antifascist
#Cancer #Metastasis #Leukemia #AML #STAT3 @stoiberlab.bsky.social
Serra Hunter Lecturer Professor at Universitat de Barcelona. Interested in human population diversity.
Post doctoral researcher at University of Illinois Chicago, Pharmaceutical science department.
Assist. Prof | Leiden University | Mucosal Immunology | Human Disease | Single-Cell | Organoids | former postdoc Mark Davis & Calvin Kuo Lab at Stanfordπ vanunenlab.org π
Exploring how the environment, brain & body interact to shape human health π¬ | Faculty at Stanford & Core Investigator at @arcinstitute.org
http://www.thaisslab.com
We are an #immunology lab interested in #Inflammation @UZH_en
Messages by Burkhard Becher, @selmatuzlak.bsky.social, @luckylukelukas.bsky.social
Assistant Prof. at Stanford & Innovation Investigator at @arcinstitute.orgβ¬ | Studying metabolites and their impact on physiology and disease π¦ π§ͺ
www.arcinstitute.org/labs/levylab
Pediatric rheumatologist, scientist, husband and father, baseball fan. Studies #SJIA, #MAS, autoinflammation. Former @iowamed, @vumcpeds. He/him. Views my own.
https://www.cincinnatichildrens.org/research/divisions/r/rheumatology/labs/schulert
π¬ Assistant Prof, Pathology βͺ@Duke | Director, Clin Micro Lab
𧫠Former Clin Micro Fellow βͺ@Memorial Sloan Kettering
π©π»βπ¬ Former Postdoc @broadinstitute.org
π PhD @The Rockefeller University
Focus: Diagnostics, AMR, Structural Biology
https://linktr.ee/christycollins123
Professor of Pediatrics and Infectious Diseases Physician-Scientist #diagnosticstewardship #acuteflaccidmyelitis #enterovirus #EVD68 #EVA71 #HPeV
Views my own
https://profiles.ucdenver.edu/display/229779
Postdoc at Oslo University Hospital. Interested in autoimmunity, celiac disease, plasma cells, BCRs, TCRs, IG and TR polymorphisms and single-cell technologies.
Surviving MyalgicE, AAG & CVID to tell the story, patient & advocate w/ a JD. Into MEdical, Social & Climate Justice & Arts. Human neutrino/ PwME = MEdical apolide/ Gnarled pacer. MEssLand Worldwide https://www.tandfonline.com/doi/pdf/10.2217/fmb-2022-0031
Loving microbes, Functional Plasticity, communication, microbiome, microbiota-host interactions. Immune System. Bacteriophages, and Systems Biology. Assoc. Prof. @ Technion
Phage biologist focused on virus-host interactions and bacterial pathogenesis.
