Osama Elsallabi's Avatar

Osama Elsallabi

@oelsallabi.bsky.social

Postdoctoral @G.D’annunzio university, interested in Cellular senescence and Reproductive aging.

93 Followers  |  201 Following  |  12 Posts  |  Joined: 16.01.2025
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Posts by Osama Elsallabi (@oelsallabi.bsky.social)

In this study, we uncover the senolytic mechanism of conjugated polyunsaturated fatty acids (PUFAs), specifically α eleostearic acid (α-ESA), demonstrating that these compounds eliminate senescent cells by inducing ferroptosis, rather than classical programmed cell death pathways.

27.02.2026 10:11 — 👍 1    🔁 0    💬 0    📌 0
yICSA Webinar Series: Osama Elsallabi
YouTube video by ICSA main yICSA Webinar Series: Osama Elsallabi

youtu.be/cbqrqdFGsN8?...

17.02.2026 23:34 — 👍 0    🔁 0    💬 0    📌 0

Really grateful for the chance to share my journey across Europe and the U.S.
looking forward to it!

#ICSA #cellularsenescence #agingresearch #academia #senolytics #geroscience

05.01.2026 17:51 — 👍 1    🔁 1    💬 0    📌 0
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Had an amazing time at SenesceL 2025 in Barcelona! Great science, great talks, and so nice seeing familiar faces again. Can’t wait for next year. Big thanks to the organizers! @senescel.org

10.11.2025 22:35 — 👍 2    🔁 1    💬 0    📌 1
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Elastin-derived extracellular matrix fragments drive aging through innate immune activation @nataging.nature.com
www.nature.com/articles/s43...

29.09.2025 18:24 — 👍 3    🔁 2    💬 0    📌 0
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It was great to be at #ICSA2025Rome grateful to present my research & connect with brilliant scientists. Thanks to MarcoDeMaria, @martakova.bsky.social & Fabrizio D’Adda di Fagagna for the outstanding organization! @icsasenescence.bsky.social @yicsac.bsky.social

21.09.2025 20:03 — 👍 6    🔁 1    💬 1    📌 0
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Highlights from yICSA at #ICSA2025Rome 🌍✨
✔️Networking Social Event 🤝
✔️Special Session with career insights from @dimiccolab.bsky.social & @narita-lab.bsky.social 🙌
Thank you to everyone who joined us!
#yICSA #Senescence #ECR

20.09.2025 15:39 — 👍 11    🔁 4    💬 0    📌 1
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Excited to dive into fascinating science on cellular senescence! @yicsac.bsky.social @icsasenescence.bsky.social
#CellularSenescence #Aging #ICSA2025 #yICSA”

16.09.2025 15:03 — 👍 6    🔁 2    💬 0    📌 0
Preview
Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise Exercise-induced inflammation is regarded as a response to muscle damage from mechanical stress, but controlled immune signaling can be beneficial by promoting metabolic adaptation which, for example,...

“NIH researchers found that exercise triggers mitochondrial DNA release in muscle, activating immune pathways that boost fat-burning fibers and fight obesity—but this same response may worsen fatigue in long COVID and #ME/CFS through immune overactivation.” www.cell.com/trends/endoc...

13.06.2025 03:05 — 👍 64    🔁 29    💬 3    📌 1

Mindblowing!!!

05.06.2025 10:08 — 👍 5    🔁 1    💬 0    📌 0
EU Funding & Tenders Portal The Funding and Tenders Portal is the single entry point (the Single Electronic Data Interchange Area) for applicants, contractors and experts in funding programmes and procurements managed by the Eur...

Are you interested in joning our lab to work on #CellSenescence? You could apply for a MSCA fellowship, the call is open: ec.europa.eu/info/funding...
Get in touch!

03.06.2025 13:37 — 👍 3    🔁 2    💬 0    📌 0

🪰 The next step is to carry out a more extensive search in the drosophila fly genome.

In the long-term, this knowledge could be used to increase the success rate of assisted reproduction treatments and to develop drugs to tackle aneuploidy, which is a characteristic of many tumours.

03.06.2025 15:22 — 👍 2    🔁 1    💬 1    📌 0
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Identification of lipid senolytics targeting senescent cells through ferroptosis induction Cellular senescence is a key driver of the aging process and contributes to tissue dysfunction and age-related pathologies. Senolytics have emerged as a promising therapeutic intervention to extend he...

www.biorxiv.org/lookup/doi/1...

21.05.2025 06:32 — 👍 0    🔁 0    💬 0    📌 0
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Development of novel flavonoid senolytics through phenotypic drug screening and drug design Accumulation of senescent cells drives aging and age-related diseases. Senolytics, which selectively kill senescent cells, offer a promising approach for treating many age-related diseases. Using a se...

www.biorxiv.org/content/10.1...

21.05.2025 06:31 — 👍 0    🔁 0    💬 0    📌 0
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Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair Aging is marked by the accumulation of senescent cells (SnCs), which contribute to tissue dysfunction and age-related diseases. Senotherapeutics, including senolytics which specifically induce lysis o...

doi.org/10.1101/2025...

21.05.2025 06:31 — 👍 1    🔁 0    💬 0    📌 0

Loved the mix of science, good conversations, and familiar faces. Already looking forward to the next one!

#PhDLife #CellularSenescence #KarolinskaInstitute #yICSA #ResearchCommunity #Gratitude

18.05.2025 17:07 — 👍 1    🔁 0    💬 0    📌 0

It was really special to meet Federico Pieatrocola again, the one who first got me interested in senescence. Super grateful for that early spark. And big thanks to Francesca Castoldi for being such a great teacher when it came to lab techniques!

18.05.2025 17:07 — 👍 0    🔁 0    💬 0    📌 0
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Had the pleasure of presenting my PhD research at the yICSA Symposium at the Karolinska Institute! It was a great experience to share my work on cellular senescence and connect with so many scientists.

18.05.2025 17:07 — 👍 6    🔁 1    💬 2    📌 0
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🚨 Calling senescence researchers!
Applications are open for the #ICSARome2025
@icsasenescence.bsky.social & @yicsac.bsky.social
Travel Fellowships 🌍✈️
Need-based & merit-based awards available!
🗓️ Deadline: May 15

10.04.2025 19:01 — 👍 6    🔁 5    💬 0    📌 2