Morandi Research Group

Last day at #eucomc2025 starts with #plenary lecture @morandilab.bsky.social 🇨🇭 @ethz.ch introducing new concepts for atom and funcional transfer #Ni #organicsynthesis

10.07.2025 07:28 — 👍 19    🔁 5    💬 0    📌 0

Congrats to Ann-Sophie Paschke, Eva Meeus, Florin and our collaborators from the pharmacy institute M. Masota and @nathalie-grob.bsky.social - Late-Stage Diversification of Peptides and Peptide Drugs through Nitrogen Atom Insertion | @ChemRxiv - go.shr.lc/44mL6Kg

04.07.2025 11:10 — 👍 14    🔁 4    💬 0    📌 1

Congrats to Tanner Jankins, Barnabé Berger, Françoise A. Aouane, Sergio Barbeira-Arán, Christophe Didier, Bettina Hürlimann and Claudius Zimmer: C–H Functionalization via Single Atom Metathesis of C–H and C–X Bonds @jacs.acspublications.org pubs.acs.org/doi/10.1021/...

18.06.2025 14:05 — 👍 7    🔁 2    💬 0    📌 0

Efficient Optimization and Synthesis of Diverse Azaarenes via Nitrogen Atom Insertion under Continuous Flow Conditions We report the development of a continuous flow approach to nitrogen atom insertion. The setup is modular, enabling the rapid optimization of reaction conditions for a wide range of substrates. The mil...

Congrats to Sooyeon Moon, Julia Reisenbauer, Ann-Sophie Paschke, Alessandro Scotto, Luca Terraneo, Niklas Brenner, as well as collaborators from Spirochem AG Quentin Lefebvre, Thomas Fessard for a continuous flow approach to nitrogen atom insertion. @Innosuisse. chemrxiv.org/engage/chemr...

18.06.2025 13:57 — 👍 1    🔁 0    💬 0    📌 0

Chemodivergent C-to-N atom swap from benzofurans to benzisoxazoles and benzoxazoles Facile derivatization of biologically active compounds without prefunctionalization expands the chemical space and accelerates the discovery of new molecules. Atom swap reactions have recently emerged...

Congrats to Ann-Sophie Paschke, Stefanie Schiele, Camille Pinard, and Filippo Sandrini: Chemodivergent C-to-N atom swap pubs.rsc.org/en/content/a.... Please also check our other paper (10.26434/chemrxiv-2024-prwm8) as well Studer's work.

18.06.2025 13:43 — 👍 7    🔁 2    💬 0    📌 0

Advertisement for PhD position

My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty

08.04.2025 08:06 — 👍 21    🔁 18    💬 1    📌 1

Metal Electronics Mediate Steric and Coordination Number Effects on Palladium (II) C–X Reductive Elimination Reductive elimination is the key bond-forming elementary step in many transition metal catalyzed reactions relevant to the synthesis of pharmaceuticals, materials and fine chemicals. Metal electronics...

Congrats to @mixalhsmpogdos.bsky.social, @sevenroediger.bsky.social, @fruepp.bsky.social, Patrick, Nathalie, Fabio on this epic study of the factors governing reductive elimination - using causal inference, organometallics, electrochemistry, kinetics and DFT
@chemrxiv.bsky.social go.shr.lc/4j8O5MM

11.04.2025 20:24 — 👍 9    🔁 4    💬 0    📌 0

Palladium-Catalyzed Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds We report a new strategy for the catalytic iodination of nonactivated C(sp3)–H bonds. The method merges the concepts of shuttle and light-enabled palladium catalysis to employ aryl iodides as both hyd...

Many congrats to Emilien Le Saux for this new publication in @jacs.acspublications.org describing a catalytic approach to Transfer Iodination from Aryl Iodides to Nonactivated C(sp3)–H Bonds.
pubs.acs.org/doi/10.1021/...

08.04.2025 13:03 — 👍 21    🔁 4    💬 0    📌 0

Our @snf-fns-ch.bsky.social research project "Hypervalent iodine reagents for peptide and protein modification and applications in chemical biology" has been accepted! 2 PhD and one postdoc positions are now open @lcsolab.bsky.social For more details to apply, See:

www.epfl.ch/labs/lcso/gr...

31.03.2025 11:55 — 👍 21    🔁 4    💬 0    📌 0

Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds The synthesis of nitrogen-containing molecules through carbon–nitrogen (C–N) bond formation is critical for the discovery and preparation of medicines, agrochemicals, and materials. Here, we report th...

Many Congrats to @ybraegger.bsky.social,
Ann-Sophie Paschke, Nima Nasiri, Bence Botlik
and Francesco Felician for this masterpiece! Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds in Science, @ethzurich.bsky.social.
www.science.org/doi/10.1126/...

07.03.2025 08:50 — 👍 32    🔁 6    💬 2    📌 0

Are you inspired by complex reaction mechanisms and organometallic chemistry? At the European Symposium on Organic Chemistry (@ESOC_ISC) in Copenhagen (www.esoc2025.com) Jennifer A. Love (
@jenlove.bsky.social
) and Bill Morandi (
@morandilab.bsky.social
) will share their latest results!

03.03.2025 08:45 — 👍 3    🔁 3    💬 0    📌 0

Some Items of Interest to Process R&D Chemists and Engineers

Congrats to @sevenroediger.bsky.social and team as well as Tanner Jankins and team for having their papers highlighted this month in OPRD items of interest to process chem 😀 pubs.acs.org/doi/10.1021/...

20.02.2025 20:26 — 👍 3    🔁 1    💬 0    📌 0

It is time to say good bye to @pfritz.bsky.social. Aside from being a stellar PhD student, Patrick has contributed immensely to lab organization, You will be missed Patrick! At the same time, we are also very much excited for his new chapter in @morandilab.bsky.social . You will do great things!

31.01.2025 09:08 — 👍 12    🔁 2    💬 2    📌 0

Thank you 😀

21.01.2025 14:37 — 👍 2    🔁 0    💬 0    📌 0