Thomas Höfler

Thomas Höfler

@hoeflet.bsky.social

Infection biologist, virologist, molecular biologist. Postdoc @K-State 🦠🦠 All about #viruses and how they can do better #herpes #evolution

181 Followers 626 Following 3 Posts Joined Dec 2024
5 months ago
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Rapid glycoprotein evolution enables variant interactions in herpes simplex virus type 1 Abstract. Glycoproteins cover the surface of enveloped viruses such as herpes simplex virus 1 (HSV-1). Whilst essential for cellular attachment and entry,

New paper alert 🚨
Check out our latest article about #social interactions in #herpesvirus populations via #glycoprotein variants, now in @Virus_Evolution. Thanks to everyone involved, also to the very supportive reviewers who definitely improved the manuscript!
academic.oup.com/ve/article/1...

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6 months ago

Open postdoc position in in my lab in Berlin @mpiib-berlin.mpg.de.

Join us to push the frontier in ancient microbial genomics. Please apply until Oct 17th. Reach out in case you have any questions.

www.mpiib-berlin.mpg.de/2193291/job_...

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7 months ago
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Gonna present some exciting work on mutation rates, population bottlenecks and defective genomes. Come and see me later today for my flash talk and poster presentation at #IHW25 in #Berlin.

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8 months ago

I‘ll present my poster on „Rapid glycoprotein evolution enables variant interactions in Herpes Simplex Virus type 1“ on Thursday 17th of July at #ASV2025 in #Montreal. If you are looking for me though, due to severe weather I‘ll only arrive tomorrow 😬. See you guys tomorrow!

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8 months ago
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Complex interactions in the life cycle of a simple parasite shape the evolution of virulence Author summary Classical expectations on parasite evolution assume a trade-off between transmission rate and harm to the host (virulence), favoring parasites with intermediate virulence. However, rece...

OUT in @PLOS #Pathogens! 🦠🦟
We evolved a parasite to transmit early/late from its #Anopheles host—spending less/more time inside. We ask what this means for #transmission, social #behaviour, classical #virulence theory, and (mis)used composite virulence metrics.
#MicroSky
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doi.org/10.1371/jour...

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1 year ago

I made a starter pack for researchers who study various aspects of viral sociality. It's woefully incomplete and has lots of room to grow, so do message me if I've missed you!

go.bsky.app/3PfgjkP

#SocialViruses 🦠 🧪

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1 year ago
This is figure 1, which shows pasteurisation effectively inactivates influenza viruses in milk.

In response to the emergence of H5N1 influenza A viruses as a novel pathogen of cattle, a study in Nature Communications shows that pasteurisation of cows’ milk should effectively inactivate the virus, but that it remains infectious in unpasteurised milk. https://go.nature.com/3WRQ8fb 🧪

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