Rhien Hare, MPH

There’s still time to apply for #OptoGRC2026! 🙌

All applications are considered for support, including the opportunity for full registration coverage. Poster submissions & statements of interest encouraged!

Apply by 2/20 to maximize your chances👇
www.grc.org/optogenetic-...

Arc bioinformatics scientists @noamteyssier.bsky.social
and Alex Dobin have just released cyto, an ultra-high throughput processor specifically optimized for
@10xgenomics.bsky.social Flex single-cell data.

We are excited to make this resource open source: www.biorxiv.org/content/10.6...

We had such a great time celebrating Tian Lab student Nikki Tjahjono’s successful PhD defense last week!

Over the past six years, it has been a privilege to work with Nikki and watch her grow into an exceptional scientist, mentor, and community builder.

Congratulations, Dr. Tjahjono! 🎓🎉

Don’t miss out on the chance to present at #OptoGRC2026!

Apply to attend and submit a poster abstract to be considered for an oral presentation during the conference 🎤

Early applications are strongly encouraged! 🔽
www.grc.org/optogenetic-...

The State of Neuroscience 2025 The Transmitter presents a portrait of the field through four lenses: its focus, its output, its people and its funding.

@thetransmitter.bsky.social's portrait of the state of neuroscience presents a great opportunity to look back & reflect as we come toward the end of 2025. I'm quoted alongside leaders in the field as we reflect on the current challenges & hopes for the future: www.thetransmitter.org/state-of-neu...

🚨 Reminder: Applications for #OptoGRC2026 are now OPEN!

Don’t miss your chance to join an incredible week of science, discovery, and connection with the brightest minds in optogenetics 💡🧠

Apply now for the best chance of acceptance: www.grc.org/optogenetic-...

How genetically encoded sensors have lit up neuroscience Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.

Thanks to @nature.com for featuring our work in this piece on genetically-encoded sensors.

The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.

www.nature.com/articles/d41...

It's time to meet your #OptoGRC2026 chairs!

Co-vice chair @tinakim-neuro.bsky.social is an assistant professor at @princeton.edu who spent the summer building a van for weekend adventures 🚐✨

She's most looking forward to meeting new people & exploring areas outside of her usual wheelhouse!

A preprint out today from Arc Innovation Investigator Theo Roth, Austin Hartman, Oliver Takacsi-Nagy, and colleagues introduces CRISPR All–a unified programming language for editing human cells across all major genetic perturbation types at once.

Published today in @nature.com, @adititm.bsky.social & researchers from the @brianhie.bsky.social lab report that the large-scale genomic model, Evo, is capable of using surrounding genomic context to produce novel, functional genes, enabling an an emergent approach they've termed 'semantic design'.

The Tian Lab is headed to San Diego for @sfn.org #Sfn25!

Proud to have Postbac Fellow, Landon Lee representing us this year––if you’re attending, be sure to stop by his poster to hear more about the science we've been developing this year! ☀️🧠

🎉 Join us on Monday for the best party of the year!

The Cai-Tye Collective is throwing a bash at #SfN25 and everyone is invited!

🎉 November 17, 9pm at Parq Nightclub in San Diego. See you all there!

Early Cannabis Use Poses Risks to Physical and Mental Health Recent studies have found earlier teen cannabis use significantly increases risks for serious health problems in adulthood. Best goal: Delay or prevent cannabis use in adolescents.

Current research continues to emphasize that adolescents should not be consuming #cannabis and need to be better educated about its health impacts 🧠

Read more about the mental and physical effects of cannabis use on the brain ⬇️
www.psychologytoday.com/ca/blog/addi...

Research Project Manager I (Dr Saez's Lab) - Neurosciences in New York, NY | Mount Sinai Health Systems Mount Sinai is hiring a Research Project Manager I (Dr Saez's Lab) - Neurosciences in New York, NY. Review all of the job details and apply today!

✨ Program Manager Job Alert ✨ Join our Mount Sinai team in NYC to steer a multi-institutional neuroscience initiative aimed at understanding Bipolar Disorder.

If you’re passionate about science, data & impact we’d love to hear from you!

Learn More & Apply 👇
careers.mountsinai.org/jobs/3032351...

What does "Human-centered neural engineering and AI" mean?

It means prioritizing the patient across the entire pipeline: Discovery, Design, and Delivery of neuro-engineering treatments for psychiatric disorders.

Join me to discuss at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social

A study out today in @natgenet.nature.com from Core Investigator Luke Gilbert, Haolong Li, & others identifies PTGES3 as a critical regulator of androgen receptor (AR) protein levels in prostate cancer, revealing a potential new target for tumors that become treatment-resistant.

How mood states shift in the brain remains one of psychiatry’s biggest mysteries.

With generous support from @bipolardiscoveries.org, our @sinaibrain.bsky.social team will apply cutting-edge techniques to map these transitions—aiming to build the most precise understanding of bipolar disorder yet.

Must-read #NYBCI25 coverage by @neurotechnology.substack.com in @forbes.com.

My key takeaway on cognitive BCI: Our biggest limiting factor isn't tech—it's fundamental scientific understanding.

We can’t advance the tech until we define the disorder. Basic research must lead the way!

YouTube video by Stellate Communications 5 Years of mad science magic ✨

⚗️ @stellatecomms.bsky.social began with the idea that science deserves to be shared, understood & celebrated.

This month we celebrate 5 years of Stellate!

To my team: thank you for believing in this dream as much as I do. You’re the magic behind it all✨

www.youtube.com/watch?v=dU5P...

Published today in @natureportfolio.nature.com Biotechnology, Laine Goudy, Luke Gilbert, Alex Marson, & colleagues report an epigenetic editing platform that safely reprograms multiple genes in human T cells without many of the challenges & risks associated with traditional gene editing approaches.

What does it take to move neuroengineering breakthroughs into real-world impact?

Our workshop at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social, will explore how research, startups, and investment can come together to advance mental health care.

neuro.embs.org/2025/satellite-workshops/

In 2016, the first Opto GRC was created to bring together scientists pushing the boundaries of optogenetics research 🧠🌟

Join us to celebrate 10 incredible years of collaboration and discovery—applications for #OptoGRC2026 are now open!

Apply now: www.grc.org/optogenetic-...

"It takes a village!" and I'm incredibly grateful to be a part of this one.

It was inspiring to witness the growing community driving cutting-edge #BCI research from the bench to real life at #NYBCI25

Here’s to building the future of #neurotechnology, together. 🧠⚡

For decades, human genome editing has been limited to small, localized modifications.

Today, in a new paper published in @science.org , researchers from Arc's Hsu lab show that bridge recombinase technology is capable of large-scale genomic rearrangements in human cells.

In another preprint from the @brianhie.bsky.social Lab and @synbiogaolab.bsky.social, they introduce Germinal, a generative AI system for de novo antibody design.

Germinal produces functional nanobodies in just dozens of tests, making custom antibody design more accessible than ever before.

This week is the 16th Annual National Postdoc Appreciation Week, and we couldn't be prouder of our postdocs in the Tian Lab! ✨

Our postdocs drive forward research, plan and lead projects, mentor students, present and publish work, and much more. I am grateful for you every day!

#NPAW2025

YouTube video by Stellate Communications Stellate Communications Reel

I was going to write a whole post about all this incredible work with all these amazing scientists and organizations, but I’ll just leave @stellatecomms.bsky.social design sizzle reel here.

It speaks for itself.

youtu.be/x2O7DkpIoCA?...

In a new preprint from @brianhie.bsky.social's lab, the team reports the first generative design of viable bacteriophage genomes.

Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.

A behind-the-scenes peek at the new O’Connell Lab website 🐸

Stellate's Web & Design team made magic happen in delivering the Stanford group's new fully custom rebrand— balancing clean and professional with vibrant and playful!

Check it out: www.laurenoconnelllab.com

Lin Tian Lab - Max Planck Florida Institute for Neuroscience - Research Lin Tian's Lab invents, optimizes, and shares innovative molecular tools and biosensors with the ultimate goal of uncovering new treatments for neuropsychiatric diseases.

💡 The future direction of these sensors goes beyond optimization. We want to combine sensor use with technology such as fiber photometry in order to measure the full range of dynamics such as tonic and phasic neuromodulator release.

➡️ Learn more here: www.lintianlab.org/research#tools