Giuseppe Di Caprio

A beautiful piece of work from @ruixuan3.bsky.social and @supgokul.bsky.social presenting a light-based slicing method using a photosensitive hydrogel to image large biological samples layer by layer, preserving fine structure for full 3D reconstructions.

We’re excited to welcome Grant McClure, John Selkirk, Ben Polwart, and Robert Barry, who are undertaking their 5th-year Industrial Partnership Project on the OpenFlexure Microscope, an open-source, 3D-printed laboratory microscope designed to make high-quality microscopy accessible worldwide.

Say Hi to Nicola👋🏻🔬, our shiny new Nikon microscope. Already the most popular member of the lab... Sorry everyone else 😅

A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications.

www.nature.com/articles/s41...

Strathclyde named Scottish University of the Year and Runner-Up UK University of the Year by The Times and Sunday Times www.strath.ac.uk/whystrathcly...

The rising danger of AI-generated images in nanomaterials science and what we can do about it - Nature Nanotechnology Generative AI has made it trivial to generate fake microscopy images that are indistinguishable from real images, even for experts. As researchers in nanoscience, it is time for us to face this realit...

A bit of a terroristic view. Synthetic data isn’t all bad, it has been shown to improve classification algorithms.

P.S. We’ve got a hopefully interesting contribution to this field coming shortly. 📝 Stay tuned.
www.nature.com/articles/s41...

Two Strathclyde Uni researchers receive grants worth more than £1.8m each The two researchers have received grants worth more than £1.8m each

Big congrats to Lewis @lemackz.bsky.social and Pablo! @unistrathclyde.bsky.social www.heraldscotland.com/news/2547411...

Indeed! @biomedeng25.bsky.social

IEEE is everywhere. 🤓 #IsleofKerrera

Figure legend: Categories and capabilities of smart microscopy systems integrating real-time image analysis and feedback control. Top: Smart microscopy workflows can be classified based on the driving logic behind decision-making: Event-driven (reacting to rare biological events), Outcome-driven (using feedback-control to steer biological systems toward a desired state), Quality-driven (optimizing signal quality or imaging metrics), and Information-driven (guided by models that predict which measurements/perturbations will yield the most informative data). Middle: Central feedback loop between the microscope and an image analysis system, which continuously exchanges images and commands to guide acquisition dynamically. Bottom: Key control actions enabled by smart microscopy: adjusting imaging modality (e.g. switching from brightfield to fluorescence, adjusting sampling rate), repositioning the field of view (e.g. tracking, drift correction), optimizing acquisition settings (e.g. adaptive optics), and performing photomanipulation (e.g. FRAP, ablation, optogenetics).

🔬🧠 Our paper on smart microscopy & the issue of interoperability! www.biorxiv.org/content/10.1... LONG THREAD WARNING: Smart microscopy uses real-time image analysis to automatically guide the acquisition or perturbation of the sample (closed feedback-control loop). Many applications exist:

rBio: Reasoning Model Trained on Virtual Cell Simulations Scientists can ask complex biological questions in plain language and get predictions about gene interactions.

Intrigued to know more about rBio, a new AI model from CZI that uses virtual cell models to explore biology in silico.
chanzuckerberg.com/blog/rbio-re...

Smart Microscopy: Current Implementations and a Roadmap for Interoperability Smart microscopy is transforming life sciences by automating experimental imaging workflows and enabling real-time adaptation based on feedback from images and other data streams. This shift increases...

www.biorxiv.org/content/10.1...

We just got a new toy 🔬🤓

GrantNet would be fairer, since he came up with it. 😁

So touched by this gift from our summer intern Grant McClure. Naturally, we ended up discussing how the architecture isn't quite correct... People do love feedback on their gifts, don't they 😅 #lifeofsheldon

Version control: how I combat the rise of generative AI in the classroom I was worried that ChatGPT was composing my students’ essays. Looking at the writing process step by step can combat this and has other benefits, too.

This sounds like a good idea: Instead of students submitting only a final PDF of their dissertation, have them submit with full version history. Makes AI use easier to spot, and you get to see their actual writing process. Could be a game‑changer for assessment.
www.nature.com/articles/d41...

Grateful for the chance to speak on computational microscopy and ML/AI in imaging. Thanks for having me! #SOMC25 #Microscopy #AI

One of the MEng students in the group opened his project slides with an AI-generated image of me trying to break a CNN and honestly, it’s kind of perfect 🥹😂 So proud (and already slightly roasted).

New review paper out! Proud to co-author with @optophysakhil.bsky.social and @gailmcconnell.bsky.social a deep dive into Fourier Ptychographic Microscopy (FPM), from physics to cutting-edge algorithms & medical imaging applications. onlinelibrary.wiley.com/doi/epdf/10....

Seriously need to know what magical places you all travel to have "limited email access".

Out today in @natmethods.nature.com : Spotiflow, our transcript localization method for imaging-based spatial transcriptomics. Led by amazing PhD student @albertdm.bsky.social, joint work w @gioelelamanno.bsky.social at EPFL / @scadsai.bsky.social
www.nature.com/articles/s41...
rdcu.be/epIB7

University of Glasgow illuminated in rainbow pride flag colours

Queer teachers are living proof of queer futures - created by Adrian

A group of people standing outside of the univeristy of glasgow main building

Lauren stands in front of a presentation screen, it's titled: Category is... staff and student experiences of rainbow office hours.

As we mark #PrideMonth, we take this moment to celebrate LGBTQ+ identities and also reflect on the ongoing work to make our universities places where every member can thrive.

Thank you to colleagues for co-authoring this powerful piece on Rainbow Office Hours ➡️ gla.ac/3Zio6uv

#OneTeamUofG 🏳️‍🌈 🏳️‍⚧️

Research away day with a view. @unistrathclyde.bsky.social

YouTube video by University of Glasgow University of Glasgow Pride Month Message #OneTeamUofG

"Pride is about visibility, solidarity, & hope."

A joint message of support from UofG's LGBT+ Equality Champion Prof Moira Fischbacher-Smith & @glasgowunisrc.bsky.social's VP Student Support @irisduane.bsky.social during a time of uncertainty & challenge globally.

Happy #PrideMonth 🏳️‍🌈🏳️‍⚧️ #OneTeamUofG

See our recent article in @natmethods.nature.com on a machine learning model #DeepSPT to rapidly precisely and automatically analyze anomalous diffusion. The model predicted biological identity from diffusion alone indicating that motion beside structure defines function.

At the Center of the Cellular Microenvironment’s impact workshop. Really enjoying the space to think together about where cell engineering and mechanobiology are headed. @theglasgowcemi.bsky.social @unistrathclyde.bsky.social

Excited to announce this new paper from the Kirchhausen and Hatzakis labs on DeepSPT, a deep learning framework for single-particle/vesicle tracking. www.nature.com/articles/s41...

For a quick summary of the paper, read the Research Briefing here:
www.nature.com/articles/s41...

New from the Dai and Li labs: Meta-learning-empowered reflective lattice light-sheet virtual structured illumination microscopy (Meta-rLLS-VSIM) offers near-isotropic resolution for fast and versatile super-resolution imaging of subcellular dynamics www.nature.com/articles/s41...

Ring deconvolution microscopy: exploiting symmetry for efficient spatially varying aberration correction - Nature Methods Ring deconvolution microscopy leverages symmetry to provide fast and straightforward spatially varying deblurring and offers improved speed and image quality compared to standard approaches across div...

You know when your deconvolution assumes the PSF is uniform, but your microscope knows better? Ring Deconvolution Microscopy says: embrace the symmetry. #microscopy #computationalimaging #deeplearning www.nature.com/articles/s41...