Aria Vaishnavi, PhD

Eric Edison Gardner Received the 2025 Young Investigator Award - IASLC - OncoDaily Eric Edison Gardner Received the 2025 Young Investigator Award - IASLC / 2025 Young Investigator Awardees, cancer, Eric Edison Gardner, IASLC, International

International Association for the Study of Lung Cancer (IASLC) - Eric Edison Gardner Received the 2025 Young Investigator Award

@iaslc.bsky.social

oncodaily.com/career/eric-...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #IASLC #YoungInvestigatorAward

Hats off to superstar summer students @vskyeagle.bsky.social and Emmanuel O for fantastic rotations and presentations. So proud of you! @mdanderson.bsky.social

Omg

ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.

A broad group of National Institutes of Health (NIH) public servants have taken action with the "Bethesda Declaration" that targets the NIH and HHS Leadership. Join these courageous and committed professionals by adding your name now. actionnetwork.org/forms/add-na...

That’s a great question! We haven’t really looked yet but could definitely explore that!

Collectively, this work provides evidence for an important role for ERBB family signaling in the genesis and maintenance of BRAFV600E-driven lung cancers, and the potential for future therapeutic improvement by rational combination targeting of these pathways.

Here, using genetic and patient-derived mouse models, we reveal that activation of BRAFV600E oncoprotein drives transcriptional upregulation of ERBB family ligands in the AT2 cells of the lung. This ERBB autocrine loop serves to support the initiation and maintenance of BRAFV600E tumors in the lung.

BRAFV600E-Driven Lung Tumorigenesis Requires Ligand-Mediated Activation of ERBB Receptor Signaling Secretion of ligands of the human epidermal growth factor (EGFR) family of receptors or erythroblastic leukemia viral oncogene family (ERBB1-4) is a feature common to many cancer cells. However, our u...

I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.

www.biorxiv.org/content/10.1...

Despite its cancer-fighting mission, NCI starts to feel Trump administration budget ax Trump cuts are hitting the National Cancer Institute, affecting a hotline for patients, cancer.gov, advisory panels, clinical trial recruitment.

Despite its cancer-fighting mission, NCI starts to feel Trump administration budget ax www.statnews.com/2025/05/07/t...

The Unbelievable Scale of AI’s Pirated-Books Problem Meta pirated millions of books to train its AI. Search through them here.

Acc to an article in The Atlantic, Meta, using LibGen, appears to have pirated millions of articles and book chapters to train AI. The Atlantic provides a searchable link, and I find 199 of my books, book chapter, review article and major publications, all used without my permission.
www.theatlant

Fantastic talk today by the legend herself: so great to have her in house!! Don’t mind me while I fangirl over THE Dr. Rushika Perera! @rushika-perera.bsky.social @anirbanmaitra.bsky.social

Save the Date! Cancer Molecular Therapeutics Research Association Annual Meeting in Utah July 13-17. Please register today. Incredible line up of speakers: RT! @andreaventura.bsky.social @rjdlab.bsky.social #lcsm

FINAL LOCATION UPDATE: Stand Up for Science 2025

The final location for Stand Up for Science on 3/7 is Jan and Dan Duncan Neurological Research Institute (NRI).

Please disregard announcements about TMC Commons.

Join us at NRI: maps.app.goo.gl/y6DbDuFMr4CK...

Looking forward to seeing you there!

You hit the nail on the head with this post!

Join us in Houston for Stand Up for Science 2025 on March 7 at 12:00 PM in Texas Medical Center Commons. This event is organized in solidarity with scientists nationwide. #StandUpForScience2025 #ScienceAdvocacy

The NIH Memo That Undercut Universities Came Directly From Trump Officials NIH officials said they were given no advance warning and less than an hour to post the memo publicly.

It’s @katherinejwu.com with the receipts.

The NIH memo undercutting the NIH came directly from Trump officials.

www.theatlantic.com/health/archi...

a man wearing a top hat and a purple jacket is asking for more . ALT: a man wearing a top hat and a purple jacket is asking for more .

ATTENTION

If you are on a study section that was scheduled to meet, please post or DM me with information regarding:

1. The name of the study section

2. The scheduled date

3. Whether the meeting actually occurred

THANK YOU

Are the Trump team’s actions affecting your research? How to contact Nature Use this form to share information with Nature’s news team, or to make suggestions for future coverage.

Are you a scientist whose work is being affected by changes in the Trump administration? Get in touch with @nature.com reporters @maxkozlov.bsky.social @dangaristo.bsky.social @heidiledford.bsky.social Jeff Tollefson & yours truly.

Let us know what's on your mind & what we should be writing about.

Graphic with the following copy: University of Utah Research Economic Impact 768M, 689MA The U Research Enterprise is an Engine for Economic Grown and Development 664M- БОЗМ- 551M In Fiscal Year 2023, The U Hit a Historic High of $768M in Research Funding Awards U of U Research Boosts the Economy and Creates Jobs: $248M Research Salaries & Wages GENERATES $328M Million in Indirect & Induced Labor Income 8340 Employees $32M In State & Local Taxes In FY22, approximately $328 million in direct & induced labor income was generated by salaries and wages from research dollars, also generating approximately $32 million of state and local sales tax U of U Supports Small, Local Businesses in Utah and Across the Nation Vendor and Subaward Expenditures on Federal and Non-Federal Research Awards to University of Utah by Utah Counties (FY 2023) $126M 7 Start-Up Companies 囚 $28M Technical Innovation 135 Patents Issued Utah Expenditures $361,000 to $22,700,000 $106,000 to $361,000 $27,200 to $106,000 $3,900 to $27,200 $40 to $3,900 28 Products Launch

A look at the economic impact of our research:

8,340 jobs created
$248m in salaries & wages paid
$328m in indirect labor income earned
$32m in state & local taxes generated

Learn more about the impact of #UofU research: www.research.utah.edu/facts-and-fi...

Congratulations to @ginadenicola.bsky.social and @christhechang.bsky.social labs on their latest @pnas.org paper revealing context-dependent sensitivity to copper chelation! Thrilled to have collaborated with such amazing friends on the first manuscript of 2025.

🤤

“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.”
www.researchamerica.org/2023-oped-us...

My New Year’s resolution is to berate myself less for things I wish I could have done better, to learn from my mistakes, and give myself more credit for the things I did well but promptly forgot/ignored because academics love to live from crisis to crisis

Yes! I have a couple I can email you— one is from scratch and one is “pretty” defined but both work great for lung adenos

FDA grants accelerated approval The Food and Drug Administration granted accelerated approval to encorafenib.

The FDA has approved BRAFTOVI in combination with cetuximab and mFOLFOX6 for first-line treatment in patients with metastatic colorectal cancer with a BRAF V600E mutation. The approval is based on the BREAKWATER study, for which MD Anderson’s Dr. Scott Kopetz is co-PI. 1/2

Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...

🧪1/ 🚨New paper on ecDNAs from our lab!
We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇
www.nature.com/articles/s41...

Attention physician scientists! Are you interested in applying for a K08? Of course you are! I will be part of a NIH broadcasted information session featuring myself and another K08 awardee, as well as a reviewer from a K08 study section in January. See the attached flyer! And please repost!

A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer Pancreatic ductal adenocarcinoma (PDA) evades immune detection partly via autophagic capture and lysosomal degradation of major histocompatibility complex class I (MHC-I). Why MHC-I is susceptible to ...

In case you missed it.. New preprint! Our latest study identifying how MHC-I is captured by autophagy and targeted for degradation in #PDAC - It all happens at the ER ! Congrats to co-first authors Marine Berquez, Alex Li & Matthew Luy.
www.biorxiv.org/content/10.1...

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...

How many Nobel Laureates can you name? It was an absolute pleasure to spend time with friends, including Sid Mukherjee & Doug Hanahan & Sabeena Merchant, and to hear stories of science, dedication & teamwork that led to the Nobel Prize for these brilliant, compassionate, fun & badass individuals!