RCSB Protein Data Bank

Nanoparticle vaccine strategy could protect against Ebola and other deadly filoviruses
Scripps Research scientists turn nanoparticles into virus “showcases” to help the immune system recognize deadly threats.
www.scripps.edu/news...

Oxford team engineer quantum-enabled proteins, opening a new frontier In a world first, a research team led by the University of Oxford’s Department of Engineering Science has shown it is possible to engineer a quantum mechanical process inside proteins, opening the

In a world first, a research team has shown it is possible to engineer a quantum mechanical process inside proteins, opening the door to a new class of quantum-enabled biological technologies.

Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179 The structure of the orphan GPCR GPR179 bound to the extracellular matrix component pikachurin is solved.

What do you get when #NationalProteinDay and #NationalPokémonDay meet? Pikachurin. ⚡

A 2023 #ScienceSignaling study solved the structure of this extracellular protein that plays an essential role in vision.⁠
⁠
Learn more: https://scim.ag/4s82e0N

Thank you Textile Society of America for the wonderful questions! Such a pleasure reflecting on the role of textiles and tactility in my work. ❤️ textilesocietyofamerica.org/14754/member...

PDB101: Molecule of the Month: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) Cells salvage and recycle their obsolete DNA and RNA

February 28 is #RareDiseaseDay for 2026.
Some people inherit a rare defective version of HGPRT, which leads to a serious illness termed Lesch-Nyhan syndrome. Read more about Human hypoxanthine-guanine phosphoribosyltransferase at PDB-101:

PDB101: Take the PDB-101 User Survey and Win PDB-101: Training, Outreach, and Education portal of RCSB PDB

Take the PDB-101 User Survey and Win
Share your feedback and enter into a drawing for a Molecule of the Month-themed sticker set

EDUCATION CORNER: BioStinE: A Self-Training Platform in Structural Biology BioStInE is an interactive self-training platform in structural biology designed for Master’s students and researchers

Learn about BioStInE, an interactive self-training platform in structural biology designed for graduate students and researchers that is available in French and in English, in the latest RCSB PDB Education Corner

🎉 GIVEAWAY: Win a free IUCr2026 workshop registration!
Hit 20 likes = TWO winners!

To enter: Like, comment your workshop pick, tag a colleague & repost.

Winner: Feb 27 👉 event.fourwaves.com/...

#IUCR #IUCr2026 #crystallography

PDB101: Register for the February 26 Webinar on Chemical Search PDB-101: Training, Outreach, and Education portal of RCSB PDB

Register for the February 26 Webinar on Chemical Search
Learn about robust resources offered by RCSB PDB and wwPDB for accessing chemical and structural information about small molecules within PDB structures

PDB101: Molecule of the Month: H5 Hemagglutinin Sugar-binding protein on the surface of the H5N1 avian influenza virus

Since it first emerged in 1996, H5N1 avian influenza (also known as "bird flu") has led to the death and culling of millions of birds across the globe
Visit PDB-101 for a look at the protein on the surface of the H5N1 avian influenza virus

Black History Month tribute to Percy Lavon Julian, highlighting his 1935 synthesis of physostigmine and civil rights leadership.

In 1935, Percy Lavon Julian made history by synthesizing #physostigmine. Beyond his groundbreaking work as a scientist, he was also a passionate civil rights leader.
➡️Honor his legacy & explore other Black scientists' achievements: bit.ly/415kqNR. #BlackHistoryMonth

Paper Published: Delivering integrative structures alongside experimental structures and CSMs Learn how RCSB.org supports discovery, analysis, and visualization of integrative structures together with single-method experimental structures and computed structure models

Paper Published: Delivering integrative structures alongside experimental structures and CSMs
Learn how RCSB PDB supports discovery, analysis, and visualization of integrative structures, single-method experimental structures, and computed structure models

PDB101: Exploring the Workhorses of Biotechnology: Using RCSB.org to analyze plastic-degrading enzymes PDB-101: Training, Outreach, and Education portal of RCSB PDB

PDB-101 materials explore how researchers are using biology in industry.
Watch a webinar to start Exploring the Workhorses of Biotechnology

PDB101: How Structural Biologists and the PDB Drive Innovation PDB-101: Training, Outreach, and Education portal of RCSB PDB

How Structural Biologists and the PDB Drive Innovation
Submit your IUCr2026 abstract to MS001 by to share how structural science impacts scientific discovery
Abstract submission now extended to February 22

Music inspires proteins and scientists alike A symphony of proteins and an orchestra of scientists

Music inspires proteins and scientists alike
A symphony of proteins and an orchestra of scientists

Bacterial histone assemblies from Bdellovibrio bacteriovorus (purple, end-on binding mode from pdb_00008fw7 and pdb_00009ezz shown in middle row, and center-binding mode from pdb_00009f0e shown in bottom row) and Leptospira perolatii (pink, pdb_00009qt1 and pdb_00009qt2).

Surprisingly, histones have also been characterized in bacteria, including a bacterium found in soil and aquatic environments and in a spiral-shaped gram-negative bacterium
More at Molecule of the Month: pdb101.rcsb.org/motm...

Missed the Deadline? Snow Problem! We've extended abstract submissions to February 22, 2026. One more week to get your research into IUCr2026.

No registration required to submit. Papers first, logistics later.

📅 New deadline: Feb 22

👉 Submit now: event.fourwaves.com/...

Fellows-to-Faculty Awardee Sama Ahmed Studies the Neuroscience of Multitasking Simons Foundation Fellows-to-Faculty alumnus Sama Ahmed spoke with the foundation about his experiences with the fellowship.

I need to know more about the neuroscience of multitasking...

Workshop attendees

Building the Future of Structural Biology in Africa Through Training and Partnership from Protein Society
mailchi.mp/proteinso...

PDB101: Molecular Valentines PDB-101: Training, Outreach, and Education portal of RCSB PDB

Download and share our PDB-inspired collection of molecular valentines

➡️ 4 days until the IUCr2026 abstract deadline! You do not need to register to submit your abstract for Calgary before midnight on Feb 15.

➡️ Submit here: event.fourwaves.com/...

How X-rays and crystals revealed the true nature of things - NobelPrize.org The story behind the 100-year-old discovery that continues to render Nobel Prizes.

Very excited to share my love of crystallography in this article celebrating over 100 years of X-ray methods and the Nobel Prize for BBC and the Nobel Foundation:

www.nobelprize.org/stories/x-ra...

Announcement: Ligand Expo To Be Retired February 13, 2026 Users should transition to RCSB PDB and wwPDB services as soon as possible

Reminder: Ligand Expo To Be Retired February 13, 2026
Users should transition to RCSB PDB and wwPDB services as soon as possible
Details:

New PDB Beta Archive Available for Testing The beta archive is organized around and in support of the transition to extended PDB IDs. The directory structure will replace the current PDB Archive when all 4-character PDB IDs have been assigned.

Adopt early: New PDB Beta Archive Available for Testing
The beta archive supports and is organized around the extended PDB ID transition
The directory structure **will replace the current PDB Archive** when all 4-character PDB IDs are assigned
Details:

Today is the International Day of Women and Girls in Science. AWIS members are sharing the advice they wish they’d received at 13. What would you tell your 13-year-old self? https://awis.org/celebrating-women-and-girls-in-science/
#WomenInScience

Two Harmful Variants Can Restore Protein Function
Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon could occur in four percent of human genes.
www.the-scientist.co...

"Let's align our coordinates" valentine with Oxytocin receptor ("love hormone") aligned with vasopressin receptor

Use RCSB PDB's Pairwise Structure Alignment tool to compare existing PDB structures or Computed Structure Models (or upload a local file) #LoveDataWeek
www.rcsb.org/alignment

For #BlackHistoryMonth, we’re partnering with scholars to highlight and connect Black scientists worldwide.

Explore the Index of Inspiring Black Scientists to find collaborators, mentors, speakers, and new research.

Explore the Index.

👉 https://ow.ly/3xrw50Y8lha

Valentine that reads "All is FAIR in love and data"

Happy #LoveDataWeek !
Celebrate with World Data System and their Feb 10 webinar
"Persistent Identifiers: Enabling Trust & Discovery in Research Data"
Details: ow.ly/XCrT50Y0ABG

He made beer that’s also a vaccine. Now controversy is brewing An NIH scientist’s maverick approach reveals legal, ethical, moral, scientific and social challenges to developing potentially life-saving vaccines.

He made beer that’s also a vaccine. Now controversy is brewing
A scientist’s unconventional project illustrates many challenges in developing new vaccines