Gabriel Cara Fuentes's Avatar

Gabriel Cara Fuentes

@carafuentes-neph.bsky.social

Peds Nephrologist at Nationwide Children's Hospital. Trying to redefine idiopathic nephrotic syndrome and discover new therapies

562 Followers  |  512 Following  |  8 Posts  |  Joined: 18.11.2024  |  1.87

Latest posts by carafuentes-neph.bsky.social on Bluesky

Featured Researcher: Diana Zepeda-Orozco, MD โ€“ Pediatrics Nationwide

pediatricsnationwide.org/2025/10/23/f...

30.10.2025 15:23 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Pediatric nephrology is currently facing a shortage of physicians and unfilled fellowship positions. In this month's #ASNKidneyNews, one resident shares their perspective. kidney.pub/KN1710-05

17.10.2025 16:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com

15.10.2025 06:33 โ€” ๐Ÿ‘ 444    ๐Ÿ” 141    ๐Ÿ’ฌ 16    ๐Ÿ“Œ 39
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APRIL is key ๐Ÿ”‘ in the development of Antibody-secreting B lymphocytes ca. 2018 from @JASN_News
#IgAN #Nephpearls #RKDSummit #NephSky

๐Ÿ‘‰ pubmed.ncbi.nlm.nih.gov/29326157/

11.10.2025 18:11 โ€” ๐Ÿ‘ 7    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Elizabeth Kiernan, MD - Endothelium in Kidney Health and Disease
YouTube video by University of Washington Division of Nephrology Elizabeth Kiernan, MD - Endothelium in Kidney Health and Disease

Dr. Liz Kiernan talks us through "Endothelium in Kidney Health and Disease," by reviewing #kidney vasculature #physiology and eGFR, structure and function of #endothelium, #pathophysiology and signaling, #biomarkers and #therapeutics. @uwmedicine.bsky.social #nephsky

Watch: youtu.be/b1Nr0QRcVeQ

02.10.2025 18:57 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Progression of Coronary Artery Calcification and Risk of Clinical Events in CKD: The Chronic Renal Insufficiency Cohort Study

bit.ly/48yjx4v #OpenAccess

27.09.2025 22:00 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

And itโ€™s live

Iptacopan in C3GN makes it to @thelancet.com

www.thelancet.com/journals/lan...

#NephSky

26.09.2025 09:37 โ€” ๐Ÿ‘ 23    ๐Ÿ” 11    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Dark Teal background with white circle in middle with yellow border. In the circle it says C3G Awareness Day. Under the circle there is a hashtag #C3GAwarenessDay, and the text Every rare kidney disease deserves to be seen.

Dark Teal background with white circle in middle with yellow border. In the circle it says C3G Awareness Day. Under the circle there is a hashtag #C3GAwarenessDay, and the text Every rare kidney disease deserves to be seen.

Today is #C3GAwarenessDay! At ISGD, we stand with people living with this rare kidney disease. As a medical society for #GlomerularDisease experts, we're committed to raising awareness and moving the science forward to bring more hope and solutions to the C3G community. #C3G #ISGD

25.09.2025 15:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Clinical Endpoints for Glomerular Diseases from
@hjanders.bsky.social
#GlomConHawaii ๐ŸŒŠ #Nephpearls #NephSky

22.09.2025 21:04 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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โžก๏ธ Randomized, Double-Blind, Placebo-Controlled Phase 2a Study Assessing the Efficacy and Safety of Felzartamab for IgA Nephropathy www.kidney-internati...

18.09.2025 13:46 โ€” ๐Ÿ‘ 7    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV) This article is published as part of a supplement sponsored by Kidney Disease: Improving Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of the authors and do not...

The @kdigo.org IgA guidelines published www.kidney-international.org/article/S008...

We discussed them with Jon Barratt here: youtu.be/OChs5BcTEGE?... on #NephGR

18.09.2025 16:20 โ€” ๐Ÿ‘ 16    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Hey itโ€™s me!

05.09.2025 22:52 โ€” ๐Ÿ‘ 9    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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In Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus | NEJM In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi...

In Vivo CD19 CAR T-Cell Therapy for Refractory Systemic Lupus Erythematosus | New England Journal of Medicine www.nejm.org/doi/full/10....

18.09.2025 00:40 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Commentary
Distinguishing signal from noise: a new era of autoantibody testing in podocytopathies requires thoughtful approaches
Ghasemi M and Weins A

doi.org/10.1016/j.kint.2025.05.026

Original article: doi.org/10.1016/j.kint.2025.02.028

#MedSky #NephSky #FSGS #IgG #IgM #minimalchangedisease

04.09.2025 18:37 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿšจ Attention Mount Sinai Postdocs! ๐Ÿšจ
THIS WEEK is your final opportunity to apply for the Kiiln Innovation Award! ๐ŸŽ‰
Submit your application by this Friday!
We want to support your innovative journeys. Letโ€™s push the boundaries together! ๐Ÿ’ก @spocuaw.bsky.social @mountsinainyc.bsky.social

03.09.2025 17:00 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Glucocorticoid Exposure and Infection in Children and Adults With Glomerular Disease: Findings From the Cure Glomerulonephropathy Study

bit.ly/3DHbXai (FREE)

29.08.2025 22:01 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Daratumumab Efficacy in Steroid-Resistant Nephrotic Syndrome Correlates with CD38+ B-Cell Depletion The anti-CD38 monoclonal antibody daratumumab, alone or with anti-CD20 rituximab, can induce remission in steroid-resistant nephrotic syndrome or multidrug-dependent nephrotic syndrome.1 However, the ...

Daratumumab Efficacy in Steroid-Resistant Nephrotic Syndrome Correlates with CD38+ B-Cell Depletion

www.kireports.org/article/S246...

21.08.2025 06:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Introducing our keynote speakers! #VascularBiology2025
Submit your science by the end of today!
Visit NAVBO website to know more
www.navbo.org/vb2025/

11.08.2025 20:02 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Multi-omics insights of immune cells in the risk and prognosis of idiopathic membranous nephropathy - Communications Biology Multi-omics approach, immunoflurescence, and scRNA-seq link CD39+ Tregs to idiopathic membranous nephropathy (IMN) risk and poor prognosis. Machine learning models based on CD39+ Treg signature genes ...

Multi-omics insights of immune cells in the risk and prognosis of idiopathic membranous nephropathy
#nephsky
www.nature.com/articles/s42...

10.08.2025 04:52 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

A new publication from our team showing that PTEN modulates bladder antimicrobial defenses against UTI @globaluti.bsky.social

06.08.2025 20:25 โ€” ๐Ÿ‘ 8    ๐Ÿ” 2    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 0
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Happy Friday! Registration for the C3G & Immune Complex MPGN Updates: Where We Are & Where We Are Headed on โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚October 3rd is now open! Feel free to sign up using the โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚โ€‚following link: www.columbiamedicine...

25.07.2025 20:12 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Clinical relevance of computationally derived tubular features and their spatial relationships with the interstitial microenvironment in minimal change disease/focal segmental glomerulosclerosis Visual scoring of tubular damage has limitations in capturing the full spectrum of structural changes and prognostic potential. Here, we investigated if computationally quantified tubular features can...

Clinical relevance of computationally derived tubular features and their spatial relationships with the interstitial microenvironment in minimal change disease/focal segmental glomerulosclerosis - Kidney International www.kidney-international.org/article/S008...

20.07.2025 16:19 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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In a recent #ASNJASN article, authors report that ephrin-B1 at slit diaphragm suppresses cdc42 activity by preventing the interaction of Par6 with cdc42 and functions to keep the specialized phenotype of podocytes. Read more: kidney.pub/JASN0728 #BasicResearch

20.07.2025 16:00 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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"As a pediatrician, it's important to highlight the established risk factors for UTI in kids. As a scientist it's important to highlight recent clinical and translational UTI research"

Sound interesting? You can catch Dr. @kidneytweets.bsky.social' #UTIhour talk on UTIGA.org/upcoming

11.07.2025 13:32 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post Doctoral Scientist - Kidney Disease Overview: The Cara Fuentes Labโ€™s focus is on Idiopathic Nephrotic Syndrome and the goal is to identify novel predictive and therapeutic targets to help individualize patient care and provide more accu...

Job alert! We are looking for a postdoc to study the interplay between immune cells and the kidney in Nephrotic Syndrome. Click below for more details:

nationwidechildrens.wd5.myworkdayjobs.com/en-US/NCHCar...

17.07.2025 00:35 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A new #review offers insight into endothelial progenitor cells: promising biomarkers and therapeutic agents with diverse potential applications in regenerative medicine. kidney.pub/JASN0792 #ASNJASN

11.07.2025 14:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Linda Baker wearing her white lab coat and standing in front of a glass window

Linda Baker wearing her white lab coat and standing in front of a glass window

Dr. Linda Baker & team @nationwidekids.bsky.social have generated the 1st iPSCs from children with 2 distinct & rare genitourinary conditions: #prunebellysyndrome & posterior cloaca Type B. Findings are published in the journal Stem Cell Research. #PedsUro pediatricsnationwide.org/2025/04/22/c...

08.07.2025 14:55 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data ๐Ÿงช doi.org/10.1101/2025...

03.07.2025 15:39 โ€” ๐Ÿ‘ 128    ๐Ÿ” 43    ๐Ÿ’ฌ 10    ๐Ÿ“Œ 1
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Inflamed endothelial cells express S1PR1 inhibitor CD69 to induce vascular leak Inflammation disrupts endothelial barrier function and causes vascular leak into the tissue parenchyma. Sphingosine 1-phosphate receptor-1 (S1PR1) in endothelial cells (EC) is a key inducer of endothe...

Latest paper from the lab - CD69 in endothelial cells..Inflamed endothelial cells express S1PR1 inhibitor CD69 to induce vascular leak - Journal of Biological Chemistry www.jbc.org/article/S002...

04.07.2025 17:02 โ€” ๐Ÿ‘ 20    ๐Ÿ” 7    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1
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Kidney Function and Cerebral Small Vessel Disease

bit.ly/HeinzeRL25 (FREE)

@felenae.bsky.social @petersenm.bsky.social #CKD

02.07.2025 10:02 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@carafuentes-neph is following 20 prominent accounts