Masa Sakata

Personalised & optimised therapy (POT) algorithm using five cognitive and behavioural skills for subthreshold depression - npj Digital Medicine npj Digital Medicine - Personalised & optimised therapy (POT) algorithm using five cognitive and behavioural skills for subthreshold depression

An apparently fully automated generative AI analysis of our paper on precision psychotherapy (www.nature.com/articles/s41...) popped up in my mailbox. I think I am allowed to cite it here: bgpt.pro?q=Paper%20Re... (if not, pls let me know, BGPT!). It's amazingly accurate.

Personalised & optimised therapy (POT) algorithm using five cognitive and behavioural skills for subthreshold depression - npj Digital Medicine npj Digital Medicine - Personalised & optimised therapy (POT) algorithm using five cognitive and behavioural skills for subthreshold depression

Evidence-based personalized & optimized CBT skills for depression, based on a trial of 4469 adults. The Resilience Training App will augment the efficacy by 35% overall over the group average best, and by 64% for those whose best option wasn’t this group average best!
www.nature.com/articles/s41...

All five skills of behavioral activation, cognitive restructuring, problem solving, assertion training and behavior therapy for insomnia worked differentially for depression (primary outcome), anxiety, insomnia and well-being. The follow-up rate was 97% at week 6 and adherence to the app was 84%.

The master protocol design, involving four 2x2 factorial trials, and the digital platform contributed to the successful completion of this RESiLIENT trial. Scalable. Affordable. Global. @wlutzpsyres.bsky.social @pimcuijpers.bsky.social @alexiswhitton.bsky.social @masasakata.bsky.social

Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial - Nature Medicine A trial that used a master randomized design found that the skills commonly found in smartphone-based cognitive behavioral therapy, when tested alone or in combination with behavioral activation, were...

Published today in Nature Medicine. In one of the world’s largest RCTs of its kind (n=3,936), a smartphone app teaching 5 key cognitive-behavioral therapy skills improved subthreshold depression—and the effects lasted 6 months.

www.nature.com/articles/s41...

Depression is preventable. Our individual participant data meta-analysis based on >7000 participants proved that psychological interventions reduce the incidence of depression within a year from 10% to 6%. authors.elsevier.com/sd/article/S...