Aakanksha Singhvi

Aakanksha Singhvi

@singhvilabglia.bsky.social

Associate Prof @Fred Hutch (+ @UW_NBio) Glia fascinate me. Worms are rad. singhvilab.org

2,090 Followers 425 Following 69 Posts Joined Nov 2024
2 months ago

This is so cool! Congratulations @krishnanyamuna.bsky.social and Krishnan lab team!!

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2 months ago

Closing out my year with a journal editor shocker 🧵

Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...

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3 months ago

On my list!! Excited to watch Flash, Flash, doing a hundred yard dash!!

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3 months ago
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From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...

C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront"
www.pnas.org/doi/10.1073/...

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3 months ago
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

The open source spirit of the worm community makes it so special - and so powerful for discovery! Great account of the impact of the community tools and databases had and have on understanding fundamental biology! 🪱 www.pnas.org/doi/10.1073/...
Important to keep these resources funded!

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3 months ago
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210K views · 5.7K reactions | Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told ... Throwback to 2018 when physics laureate Donna Strickland started her banquet speech by talking about Cyndi Lauper's song 'Girls Just Want To Have Fun'. Strickland told us how enjoyable she found...

Yes, lab life is truly so much fun! So nicely said by Donna Strickland: www.facebook.com/reel/8264683...

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4 months ago

Congratulations!!

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4 months ago
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If said women work for your competitors, I guess maybe

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5 months ago

Reaffirming the value of model organisms in training scientific minds @ishmailsaboor.bsky.social exactly what we were talking about re your #Celegans background setting you up for creative work in other systems! www.nature.com/articles/s41...

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5 months ago
Photo: Cecilia Odlind

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...

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5 months ago
Rhythmic metabolites in the E19 SCN peak during the day. Majority of rhythmic lipids and polar metabolites in the E19 SCN peak during the day, while there are more diverse phase clusters in the developed P28 SCN postweaning. Polar metabolites and lipids identified as rhythmic in E19 SCN (E19 clusters 1, top, and 2, bottom) were divided into subgroups based on hierarchical K-means clustering. Line plots on the left show traces of the normalized level of each rhythmic compound in each corresponding cluster. Bar plots on the right represent the lipid classes and polar metabolites in each rhythmic cluster.

How are #circadian rhythms established during development? This study shows that maternal metabolic signals oscillate in the fetal #SCN before the endogenous #clock becomes functional, offering a plausible mechanism for maternal entrainment of the developing clock @plosbiology.org 🧪 plos.io/3VD45fZ

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5 months ago
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What if NIH had been 40% smaller? Replaying history with less NIH funding shows widespread impacts on drug-linked research

This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...

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5 months ago

Congratulatioms, @needhibhalla.bsky.social !!

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5 months ago
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In situ Proteomics Unveils Specialized Domains for Extrasynaptic Signaling on Neuronal Cilia Neuronal cilia have emerged as crucial signaling hubs, yet their molecular composition and integration with synaptic communication remain poorly understood. Using a newly developed Arl13b-TurboID mous...

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures.
@nachury.bsky.social
www.biorxiv.org/content/10.1...

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5 months ago
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Thrilled to share our new paper @cp-cell.bsky.social:
“Microglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.”

This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling.

🔗 www.cell.com/cell/fulltex...

Faust et al., Cell 2025

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6 months ago

Happy Anniversary! 🎉

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6 months ago

A friendly reminder that the NIH Public Access Policy IS NOT “you must publish open access” but rather “you must ensure your copy of your paper is deposited into PubMed Central.”

Yes, it is very confusing. Yes, you should be able to do that deposit yourself without paying anything to a journal.

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1 year ago
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Extracellular vesicles aid in the transfer of long-term associative memory between Caenorhabditis elegans Memory formation is necessary for the survival of animals across phyla. Here, we elucidate the mechanism underlying the formation of long-term associative memory (LTAM) formed by treating Caenorhabdit...

The first one is some crazy work by @monmitabhar.bsky.social, Tanumoy, @hari-flies.bsky.social and Kamal Kishore. They eavesdropped on worm conversations and found the exciting phenomenon of movement of memory from one worm to another 2/n www.biorxiv.org/content/10.1...

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6 months ago

Congratulatioms @kavita-babu.bsky.social @monmitabhar.bsky.social and team! Super cool story!

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6 months ago
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📣 Calling all early career #neuroscientists!
@thetransmitter.bsky.social & Neuromatch are teaming up to better understand how to support #EarlyCareer Researchers. Whether you're a student, postdoc, or launching your career, we want to hear from you.
➡️ www.thetransmitter.org/early-career...

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7 months ago

Yay-fab news, congratulations, Needhi!

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7 months ago
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Mapping molecules of an unsung brain cell Fred Hutch researchers have created a gene-expression map of glial cells of the tiny worm, C. elegans, adding the missing component that completes for the first time an atlas of the entire nervous sy...

Fred Hutch researchers created a gene-expression map of glial cells in tiny worms, adding the missing component that completes an atlas of the entire nervous system of a multicellular adult animal at the molecular level. @singhvilabglia.bsky.social @manusetty.bsky.social bit.ly/47353c3

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7 months ago

Great opportunity here to build your skills and your professional network! Apply for the SciComm Interns program!
#devbiolwriteclub
@socdevbio.bsky.social

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7 months ago
Society for Developmental Biology | Strategic Planning Internship

Interested in science administration? Want to meet and work with senior members of the SDB? Want to help chart the future of the SDB? Then apply for the Strategic Planning Internship!
@socdevbio.bsky.social

www.sdbonline.org/strategic_pl...

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7 months ago

fantastic work from @melcooperphd.bsky.social - what are these beautiful networks doing in our brains?

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7 months ago
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Assistant Professor of Biology, Tenure Track Department Biology Vassar College is dedicated to providing equal employment opportunities to all applicants and employees and welcomes applications from individuals of all backgrounds. Decisions conc...

Vassar College is seeking a biologist with a focus on Developmental Neurobiology on the tenure-track. Please spread widely!

vassar.wd1.myworkdayjobs.com/en-US/Vassar...

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7 months ago
Assistant Professor - Biology Click the link provided to see the complete job description.

🚨🚨🚨PUI TT Job Alert!!

My dept at TCNJ is hiring a tenure track cell and molecular biologist. Come join my supportive colleagues, helpful staff, & fabulous students!

We're surprisingly well resourced w/excellent equipment (confocal, SEM etc) and research w/students counts towards our teaching load!

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7 months ago

Many congratulations!

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7 months ago

How cool - Congratulations @sciencenlucia.bsky.social!!

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7 months ago

Congratulations, and best wishes @eblancosuarez.bsky.social !

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