Muse en Lystrala 🔜 TAGS Festival

We're extremely excited to show you our #urbanhorror #ttrpg during this most excellent #spookyseason! Come and see us at @tagsfest.co.uk on Saturday, 25 October! #indiedev #edinburgh

Y'all @tagsfest.co.uk is in like a week and a half and I AM EXCITED #edinburgh #ttrpgs #indiedev #horror

I hate it when one small business tries to screw another small business out of money. Like fam? We're supposed to be helping each other out.

I'm a Capricorn Moon/South Node so you're in good company 🤣

JK Rowling says "ha ha.. h-heh. I won! I won!" She sits alone in the dark, bathed in the late of her computer screen. We pull back to see her in a large dark empty room. She continues "I won." Seeing the full scope of her cavernous workplace, she appears small and alone. She says, once again, "I won..."

This is how I imagine JK Rowling when she posts.

Betting Capricorn or Taurus Sun with this?

Police officers who publicly declare that they’ll quit if a mayoral candidate they dislike wins the election are (1) usually bluffing—sure buddy, toss away that paycheck and pension—and (2) exactly the sort of cops cities would be better off without, ones who don’t see themselves as public servants.

Ahhh, honestly thought the fellow on the left was Rufus from VII! Thanks for the info!

Maybe? I don't think it's XIV specific, it's just a Squex meme XD

Occasionally I wonder how different life would be if men actually listened

I can't tell if I should answer seriously or jokingly to this question

Me anytime I see G'raha Tia onscreen #ffxiv

Husband and I are watching Barbie for the first time and all I can think is that this is a film about a neurodivergent-coded healer from a world of her own who arrives and goes "what went wrong here and how tf do I fix it" and honestly that's SO relatable 😭 #WitchSky

ABSTRACT Administration of HIV-1 neutralizing antibodies can suppress viremia and prevent infection in vivo. However, clinical use is challenged by envelope diversity and rapid viral escape. Here, we performed single B cell profiling of 32 top HIV-1 elite neutralizers to identify broadly neutralizing antibodies with highest antiviral activity. From 831 expressed monoclonal antibodies, we identified 04_A06, a VH1-2-encoded broadly neutralizing antibody to the CD4 binding site with remarkable breadth and potency against multiclade pseudovirus panels (geometric mean half-maximal inhibitory concentration =0.059 ug ugml-1, breadth = 98.5%, 332 strains). Moreover, 04_A06 was not susceptible to classic CD4 binding site escape variants and maintained full viral suppression in HIV-1-infected humanized mice. Structural analyses revealed an unusually long 11-amino-acid heavy chain insertion that facilitates interprotomer contacts with highly conserved residues on the adjacent gp120 protomer. Finally, 04_A06 demonstrated high activity against contemporaneously circulating viruses from the Antibody-Mediated Prevention trials (geometric mean half-maximal inhibitory concentration = 0.082 ug ml-1, breadth = 98.4%, 191 virus strains), and in silico modeling for 04_A06LS predicted prevention efficacy of >93%. Thus, 04_A06 will provide unique opportunities for effective treatment and prevention of HIV-1 infection.

This finding potentially opens up new perspectives for the prevention and treatment of HIV infections.
• uni-koeln.de/en/universit...

The study has been published in Nature Immunology. YES, it is PEER-REVIEWED.
• www.nature.com/articles/s41...

🧪🧵⬇️

My boss: so how's our fourth quarter looking?

Me, the sales manager at the company that makes inflatable frog suits: well, you're never going to believe this, but

If you haven't already: Start weight training.

You don't have to gym rat out, or even buy equipment. Just put together some body weight exercises and do them regularly.

Hey there! This is my #TTRPG starter pack focusing on #RPGLatAm creatives from Mexico! go.bsky.app/2LiQ5T3

Ink-sketch style filtered image with vignette focus showing copper or brass gaming dice on a rough blue background. #FollowFriday in bright yellow punk/zine stamp text in upper right. Off-white quote box at bottom with the text: Seize the power in your hands. Build your world the #TTRPG community. Join us in celebrating Follow Friday. Tell us all of those you love and their works, and why you love them so. #TTRPGCommunity

🎉 It's #FollowFriday.

NEED to know:
😎 indie #TTRPG game people
📽 sweet actual play streams
🧠 unique creators & #punk minds
👽 random #geek, #queer, + #weird peeps too!

Who are they? Why do they rock? Do you have Starter Packs to recommend? Let's hear them!

Miss Major remains in need of financial support. Given her immense care for countless generations of trans folx, please contribute, if able to do so: fundly.com/missmajor

Please at least share this post to amplify this ask as Miss Major needs help! 🫂

Hello, other side of the world! How about supporting a ttrpg magazine to start your day?

doomscroll break

Happening now: we're at the Broadview ICE facility outside Chicago.

CCSO + Broadview police are telling protesters + press they can't stand on the west side of 25th Street for any reason.

We asked what the precise public safety issue is. They just said they're anticipating cars coming through.

They Will Call You Violent If your tactics disrupt the order of things under capitalism, you may well be accused of violence, because “violence” is an elastic term often deployed to vilify people who threaten the status quo. Conditions that the state characterizes as “peaceful” are, in reality, quite violent. Even as people experience the violence of poverty, the torture of imprisonment, the brutality of policing, the denial of health care, and many other violent functions of this system, we are told we are experiencing peace, so long as everyone is cooperating. When state actors refer to “peace,” they are really talking about order. And when they refer to “peaceful protest,” they are talking about cooperative protest that obediently stays within the lines drawn by the state. The more uncooperative you are, the more you will be accused of aggression and violence. It is therefore imperative that the state not be the arbiter of what violence means among people seeking justice.

I keep coming back to this passage by Kelly Hayes about violence, in particular state sanctioned violence. This is why the corporate media consistently parrots the Trump regimes 'the radical violent Left' propaganda.

I will gladly draw all of the frogs as a symbol for the movement, explicitly to take them back from the fuckers who co opted Pepe for their nazi shit.

This is HUGE! Please share so people with ME/CFS can learn about this incredible medical breakthrough!!

It not only helps develop a diagnostic test, but also points to immune and inflammatory changes to aid future treatments. After 80+ years of no treatment, there’s some hope, finally!!

Okay, this worked really well last time! I need someone from Brazil who knows about the RPG scene (specifically Vampire/White Wolf) in the early 2000s. Anybody here who could answer a couple quick questions?

No lie detected

#IndieDev #IndieGame #GameDev

My author copies of "The Sunfallen Road" for @tagsfest.co.uk came in today! I'm so pleased with how they turned out, and to share the first tale that gave rise to @triplecastgames.bsky.social's "The Hidden Keys" #horror #ttrpg. Come and see us on the 25th of October at TAGS in #Edinburgh! #BookSky

You notice all the directors/etc saying they're fine with AI are saying exactly the same things about it? Sometimes word for word.

Yeah. Those are talking points.