ICB - the journal

ICB - the journal

@immunolcellbiol.bsky.social

Cutting edge original research, provocative and exciting reviews and News and Commentary coverage on Immunology and Cell Biology

1,717 Followers 946 Following 29 Posts Joined Feb 2024
7 months ago

July's featured article from our exchange with @discovimmunol.bsky.social investigates the immunomodulatory capacity of various arginine-related metabolites.

academic.oup.com/discovimmuno...

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8 months ago

This is a great new study showing in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis

This is part of the article exchange between the BSI's @discovimmunol.bsky.social and the @immunolcellbiol.bsky.social

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8 months ago
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This month’s article exchange with @immunolcellbiol.bsky.social:

New study shows that in Crohn’s disease, aphthous ulcers trigger immune responses via bacterial uptake, not dysbiosis.

Peyer’s patches may be the ignition site 🧬

Read here: doi.org/10.1111/imcb...

#Crohns #Immunology

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8 months ago

What can we learn about airway resident memory T cells from pig models? Plenty! Find out more in this month's @discovimmunol.bsky.social Outstanding Article

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9 months ago

For this month’s article exchange with @immunolcellbiol.bsky.social: Genetic analysis causally links 22 immune cell types to PCOS. Blood metabolites mediate several effects, offering new insight into how immunity and metabolism shape disease.

🔗 doi.org/10.1111/imcb...

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9 months ago

May's featured article in our exchange with @discovimmunol.bsky.social reveals altered spatial distribution of ILCs in #endometriosis and suggests the primary role of uterine ILC3 may be endometrial repair and regeneration.

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9 months ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article for the Highlights of 2024 series, we review the latest advances in the biology of the germinal center response. These discoveries provide key insights into germinal center function a...

Our @immunolcellbiol.bsky.social "Highlights of 2024: Germinal Centers" is now out. Led by Theresa Pankhurst, we discuss some (there's never enough space for all!) neat germinal centre papers that were published in 2024, and whose findings are moving the field forward. doi.org/10.1111/imcb...

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10 months ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This study examines how Notch signaling conditions the genome landscape within activated CD8+ T cells in such a way to alter the binding pattern of transcription factors such as Gata3. This Notch dep...

For this month's article exchange with @immunolcellbiol.bsky.social we're highlighting "Notch dependent chromatin remodelling enables Gata3 binding and drives lineage specific CD8+ T cell function."

A study on how Notch signalling primes antiviral CD8+ T cell responses.

📖 doi.org/10.1111/imcb...

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10 months ago

Our April article exchange with @discovimmunol.bsky.social features a study on the relative contribution of CD28 and TCR signals on human naive and memory T cells.
academic.oup.com/discovimmuno...

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10 months ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library The Sensory Science exhibition, held during March 2024, was a collaborative effort between researchers and artists, aimed to promote the importance of inclusive and diverse scientific engagement for ....

Great new article out led by @stevipiliou.bsky.social on improving accessibility to neuroimmunology for the blind and low-vision communities! @immunolcellbiol.bsky.social

onlinelibrary.wiley.com/doi/10.1111/...

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11 months ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Amy Wilson, a Research Advisor for the Ovarian Cancer Research Foundation (OCRF) and an Honorary Research Associate at the Hudson Institute of Medical Research, began her career as a postdoctoral res....

"Your career is more than just your technical expertise—the skills, interests and motivations that make you unique, both inside and outside of research, can shape your path in unexpected ways."

Dr Amy Wilson from @ocrfaustralia.bsky.social reflects on moving into a research advisor role

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11 months ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Bone marrow ablation and reconstitution are commonly used procedures in research that are often associated with significant suffering for the animals involved, classified as ‘severe’, Category E or C...

For this month's article exchange with
@immunolcellbiol.bsky.social, we're highlighting 'Refining bone marrow ablation and reconstitution in mice.' by Penny Hawkins, James Dooley, Jessica Rodda and Colin Gilbert.

🔎 Read here: doi.org/10.1111/imcb.12847

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11 months ago

To what extent do different practices of microbial exposure affect resulting mouse phenotypes? March's Outstanding article from @discovimmunol.bsky.social shows a side-by-side comparison, enhancing understanding of naturalisation model setups and effects on the gut barrier and immune system

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this manuscript for the “Highlights of 2024” series, this is me trying to summarize recent discoveries regarding the emerging regulatory and effector roles of γδ T cells during sepsis, both in hum....

Are you ready for it?

"Highlights of 2024: γδ T cells and bad blood"

A summary of the emerging regulatory and effector roles of #gdTcells in #sepsis.

And it may also contain a few Taylor Swift references. More than 50 in fact.

Thank you so much @immunolcellbiol.bsky.social for playing along!

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article, we discuss the conceptualization, formation and management of our workplace Parents Group. We honestly reflect on both our successes and challenges. Graphic from Vivienne Samson (age....

From pipettes to playdates! @rhea-longley.bsky.social et al. share challenges and successes from establishing a parent support group in a research setting.

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library Click on the title to browse this issue

Coinciding with #InternationalWomensDay, this special feature explores persistent barriers from gender pay gaps to underrepresentation in leadership and global strategies for change, not only for women but all marginalised groups in healthcare and STEMM.

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1 year ago
In this graphic, the words diversity, equity and inclusion are shown above cartoons of five scientists/healthcare professionals. Below are cartoon antibodies, and the words healthcare and stem.

Our new special feature is out now! From reflections on starting a parents group for researchers to a case study on Indigenous student engagement in science, this special feature amplifies intersectional discussions on diversity, equity, and inclusion in healthcare and STEMM. bit.ly/41JpXKa

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This article highlights the work of our trainee-led organization, Immunologists for Gender Equity (IgEquity), which addresses gender inequities in Immunology through initiatives focused on community ....

This article from our upcoming special feature on Advancing Equity and Inclusion in Healthcare highlights the work of Immunologists for Gender Equity (IgEquity), a trainee-led organisation at @immunox.bsky.social. #InternationalWomensDay

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1 year ago

Our paper is finally out in @immunolcellbiol.bsky.social, think that transcription factor expression is all that? Well not if the genome is not prepared in a way to allow binding: here is a short 🧵1/

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1 year ago

For this month's article exchange with @immunolcellbiol.bsky.social, we're highlighting 'Exploring the dynamics of T-cell responses: a combined approach using EdU incorporation and proliferation dye dilution assay' by @jfreenvanheeren.bsky.social and colleagues

🔎 Read here: doi.org/10.1111/imcb...

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1 year ago

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this article, we identify self-reactive peripheral blood B cells in Sjögren's disease through a single-cell culture system. We find 2- to 10-fold increased frequencies of self-reactive B cells dur...

Self-reactive B cells are increased in all major stages of peripheral development in Sjögren's disease. This study from Lee et al. suggests that depleting self-reactive B cells based on B cell receptor specificity would be more efficient than targeting developmental stage in Sjögren's disease.

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1 year ago

Thanks @immunolcellbiol.bsky.social for inviting Menno and I to write this commentary about the @bogunoviclab.bsky.social paper in @nature.com on monoallelic allele expression in inborn errors of immunity
Monash Immunology and
Erasmus MC #immunosky
doi.org/10.1111/imcb...

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1 year ago

If any American immunologists want to write an op-ed for @immunolcellbiol.bsky.social on the impact of the new executive orders, please contact me

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this study, we investigated multiple cytokine combinations to boost natural killer (NK) cell proliferation as well as effector functions of proliferated NK cells against hepatocellular carcinoma a...

Modeling the response to interleukin-21 to inform natural killer cell immunotherapy

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1 year ago

Also, the submission and editorial experience with @immunolcellbiol.bsky.social was fantastic, highly efficient, very professional, and yes I am an #AusNZSocImmunol member, but if you are looking for somewhere to publish #immunologyiscool work, can't recommend highly enough.

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1 year ago

Thanks for the shout out @sjturn.bsky.social – looking forward to seeing your lab's new paper out soon!

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1 year ago
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So many good reasons to publish in ICB!

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library This manuscript, part of the Special Series “Focus on South American immunology”, provides a personal reflection on the challenges and opportunities I have encountered during my journey as an immunol...

Ten years away from “home” as a South American immunologist in Ireland: Dr Natalia Muñoz-Wolf shares insights on pursuing an international scientific career in this #ImmunologyFutures article

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1 year ago
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<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library In this study, we investigated the longitudinal dynamics and clonal expansion of circulating γδ T cells in four patients receiving anti-CD19 CAR-T cell therapy. Using single cell multi-omics analysis....

As part of our article exchange with @immunolcellbiol.bsky.social, this month we're highlighting the article 'Identification of clonally expanded γδ T-cell populations during CAR-T cell therapy'

Read the article exploring immune response after anti-CD19 #CAR-T therapy here: doi.org/10.1111/imcb...

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