@ulvmarlab.bsky.social
My team aims to expand the current knowledge about the lymph node vascular specialization and its changes in cancer & in aging -https://www.uu.se/en/department/medical-biochemistry-and-microbiology/research/ulvmar-maria - #lymphatics #metastasis #stroma
Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods
Xenium
CosMx 1k
MERSCOPE
Tissue Microarray
17 tumor+16 normal tissue
Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation
#NatComms 2025
www.nature.com/articles/s41...
Kurz, Lütge, Ludewig et al. elucidate the ontogeny of fibroblastic reticular cells and vascular smooth muscle cells in mouse lymph nodes from proliferating, CCL19-expressing progenitors & highlight the close lineage relationship of the progeny in the perivascular niche rupress.org/jem/article/...
26.11.2025 18:02 — 👍 6 🔁 2 💬 0 📌 0
Big news, EVBO community!
Our BLACK FRIDAY membership deal is live until 31 Dec 2025:
🔹 3-year full membership: €120
🔹 PhD/postdoc: €75
Join now ➜ evbo.org/index.php/me...
Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
It was a great pleasure to be a part of this new study from @halinlab.bsky.social focusing on the #Lymphatics in human skin!
16.11.2025 00:14 — 👍 15 🔁 7 💬 0 📌 0
Our @natcomms.nature.com paper is finally out! 🚀 rdcu.be/eQnYW
Using scRNA-seq and Visium HD, we mapped lymphatics in metastatic lymph nodes from breast cancer patients and discovered striking lymphatic remodeling that shapes subsequent metastasis.
Massive thanks to all collaborators!!!
Do Not miss this great @navbo.bsky.social online event😆
Specification of Endothelial Cell Phenotypes
Organized by Dr. Ralf Adams @ralfhadams.bsky.social
& Dr. Vicki Bautch
Abstract deadline November 20
members.navbo.org/calendar-of-...
Check out our new study in @jem.org on #Lymphatics using #SingleCell and #3DImaging in human skin, revealing new features of the lymphatic vascular system in #HumanBiology!
15.11.2025 22:25 — 👍 9 🔁 2 💬 1 📌 0
Reformation of science publishing: the Stockholm Declaration
A call to action for universities, academies, science organizations and funders to unite and join this effort.
Bernhard Sabel and Dan Larhammar
royalsocietypublishing.org/doi/10.1098/...
Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation #Lymphatics
New study from Bauer, Halin et al. @ethz.ch reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–based textbook description. rupress.org/jem/article/...
#Lymphatics
AI models are 50% more sycophantic than humans
go.nature.com/4ol1Quq
‼️Lymphatic Education&Research Network-GRC Scholarships‼️
LE&RN is awarding 10 × $1,000 scholarships to early investigators to attend 2026 Lymphatics GRC March 1 – March 6, 2026, Lucca (Barga), Italy.
🗓 Apply by Dec 8, 2025!
form.jotform.com/LERN/2026-gr...
Why fundamental research is fundamental to progress, seeding major breakthroughs
Editorial @nature.com this week
And 7 basic science discoveries that changed the world
nature.com/articles/d41...
nature.com/articles/d41...
"Due to a variety of circumstances...many science projects will never be finished, despite years of invested resources and effort. By carefully and strategically documenting scientific work achieved, components of unfinished projects can be salvaged and preserved to benefit future researchers." 🧪
27.10.2025 21:20 — 👍 79 🔁 40 💬 4 📌 2
Transient tissue residency and lymphatic egress define human CD56bright NK cell homeostasis @natimmunol.nature.com @Betts @ki.se @upenn.edu
www.nature.com/articles/s41...
Congrats on another great story, Annika and Niklas!
us06web.zoom.us/meeting/regi...
09.10.2025 08:04 — 👍 5 🔁 4 💬 0 📌 0
In #ASNJASN: Erythroid ACKR1 Deficiency Aggravates Immune-Mediated Kidney Disease. Read about how selective erythroid ACKR1 deficiency exacerbated disease activity in experimental glomerulonephritis via changes of myeloid lineage: kidney.pub/JASN0878 #BasicResearch
@kathiartinger.bsky.social
📣Registration is now open for the Gordon Research Seminar and Gordon Research Conference on Lymphatics 2026!
Half of the talks will be selected from submitted abstracts. Don’t miss your chance to share your work!
grc.org/lymphatics-g...
grc.org/lymphatics-c...
Goodmorning all! The EVBO board is back online! Please see our amazing speaker list and reserve the following dates for the upcoming EVBO autumn seminars. You can registration for the Zoom through the link in the email from our EVBO secretary.
08.10.2025 06:44 — 👍 2 🔁 2 💬 0 📌 0
A comprehensive molecular atlas of mesenchymal cell types in the adult mouse #liver.
-> www.embopress.org/doi/full/10....
Cell types of the adult mouse liver mapped by analysing cell type-specific molecular 'signatures', tied to anatomical location
📷 Riikka Pietilä et al @uu.se in @emboreports.org
➡️ bpod.org.uk/archive/2025...
Jane Goodall with monarch butterfly scarf
“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
― Jane Goodall
💙 RIP to a real one. My childhood hero
Jane Goodall, ethologist and conservationist, has died. She was 91
01.10.2025 18:02 — 👍 28460 🔁 7672 💬 1260 📌 1948How do cells navigate up gradients of adhesive proteins?
🤔
Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood
We show that passive friction directs cells & explains complex trajectories on gradients
👉 www.nature.com/articles/s41...
Kaska Koltowska @uu.se has identified unique DNA sequences, enhancers, which are active in lymphatic vessels. She hopes that new research will reveal new hidden secrets of the lymphatic vessel formation #research #lymphedema #medicine @lymphaticslab.bsky.social
tinyurl.com/yfk7ett5
Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray
CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339
93 common genes
lung adenocarcinoma
pleural mesothelioma
Corr. Bulk RNAseq, GeoMx
#NatureComms 2025
www.nature.com/articles/s41...
A specific gene expression program underlies antigen archiving by lymphatic endothelial cells in mammalian lymph nodes @natcomms.nature.com @cumedicalschool.bsky.social
www.nature.com/articles/s41...
🍂 Kicking off the fall seminar series! 📢 EVBO seminar, Tue 16th of September: Profs. Lena Claesson-Welsh & Hellmut Augustin. Don't miss it!
11.09.2025 09:33 — 👍 5 🔁 1 💬 0 📌 2
Flyer for Keystone meeting on Stromal immunology in health and disease, Feb 2-5th 2026.
Save the date! Keystone Stromal Immunology meeting, Feb 2-5, 2026 #KSStromal26
1. Scholarships/Short Talk Abstracts: October 7
2. Early Registration: December 3 (Save $200!)
3. Poster Abstracts: January 12, 2026 (11:59 MST)
Please share! And reach out if you have any questions.
Can't wait!
Pleased to update this - The paper is published in Cell Reports!
A long road for this one, the paper grew exponentially and evolved over a couple of years. Thanks to @makris1.bsky.social for sticking with it to untangle all the new data!
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
