Hans Popper Hepatopathology Society

Drs Maha Guindi and Maryam Pezhouh will moderate 3 talks! Classification of liver vascular tumours with Drs Mogler & Doruk; when bile ducts sclerose with Drs Pai & Patel; inflammation-infection with Drs Pezhouh & Hosseini

We're so excited for our May 9, 12 pm EST, Webinar Western Regional Event! What a stacked line-up up 🤩 Check your email for registration info!
#liversky #pathsky

Here's Dr Szczepanski with her excellent poster! #liversky #pathsky #USCAP2025

Please join us Tuesday March 25 for our second #USCAP2025 liver poster walk!🚶‍♂️🚶‍♀️

Meet Drs Isabel Fiel and Sadhna Dhingra at poster #94 at/around 930 am 📊👥

#pathsky

a black background with party time written in blue ALT: a black background with party time written in blue

Are you ready?

🥳Reception with friends PB Path & GIPS Sun March 23, 1730-1930, OMNI hotel, Marquee Room
#USCAP2025
#liversky #pathsky

Dr Alkhouri leaves us with some questions:
#USCAP2025 #liversky #pathsky

Collaboration is key! We're thrilled to be a Companion Society of @uscap.org ! Today at our #USCAP2025 meeting, we also joined forces with friends @aasldnews.bsky.social -Dr Naim Alkhouri -and the European Society of Pathology -Dr Christine Sempoux! 💚💛 #liversky #pathsky

Welcome to our new members inducted at our business meeting today at #USCAP2025! Want to become a member (fyi, no dues pathologists-in-training)? #liversky #pathsky hanspopperhepatopathologysociety.org/membership-a...

HPHS President Dr Maha Guindi and Education Committee Chair Dr Joseph Misdraji

Thank you, Dr Joseph Misdraji, for your excellent work as Chair of our Education Committee, 2023-6!

HPHS President Dr Maha Guindi and Survey Committee Chair Dr Ilke Nalbantoglu

Thank you, Dr Ilke Nalbantoglu, for your great work as Chair of our Survey Committee, 2022-5!

HPHS President Dr Maha Guindi and Membership Committee Chair Dr John Hart

Thank you, Dr John Hart, for your hard work as Chair of our Membership Committee from 2022-2025!

🥉TIE - Congratulations, Dr Xing Li, who won 3rd place at our ##USCAP2025 abstract award competition! Their work on lymphoid aggregates in HCC immunotherapy response and prognosis can be seen Wed, March 26 at the am poster session (#77). #liversky #pathsky

🥉TIE - Congratulations Dr Julianne Szczepansķi, our 3rd place #USCAP2025 abstract award winner! You can see her work on HCC mimic hepatoid intrahepatic cholangiocarcinoma at the Tuesday, March 25, am poster session (#102). #liversky #pathsky

🥈Congratulations, Dr Yulin Haw, who won 2nd place in our #USCAP2025 abstract award competition! You can catch their work on HCC with RB1 aberrations at the liver platforms on Monday, March 24, room 210C, 1115-1130. #liversky #pathsky

Dr Zhang and Education Committee Chair Dr Joseph Misdraji

🥇Congratulations, Dr Mengxue Zhang, our 1st place #USCAP2025 abstract award winner! You can see her work on genetic predisposition to oxaliplatin-induced SOS on Monday, March 24 in the am poster session #147 and at the liver platform, 9-915 Room 210C!
#liversky #pathsky

Congratulations to our 2025 Lifetime Achievement Award recipient, Dr David Kleiner!
An exceptional pathologist, researcher, mentor, leader, teacher, and friend; extremely deserving! He couldn't be with us today, so please congratulate him! 🌟 #USCAP2025 #liversky #pathsky

@ihcguy.bsky.social
Some super helpful slides independent of what tissue you look at
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social
BAP1 loss can be helpful in well-diff biliary lesions
BRAF V600E uncommon in CCA, common in BDA
CD56/NCAM stains normal small ducts/ductules and can be seen in small duct CCA too
Ki67 can be helpful in biliary proliferations
#USCAP2025 #liversky #pathsky

Molecular alterations in liver cancers:
Some can be detected by IHC (bolded)
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social
HCA subtyping:
H&E 🗝
Then IHC...especially B-catenin, GS
Remember LFABP loss can be seen in HCC
#USCAP2025 #liver

@ihcguy.bsky.social
Is it HCC?
Remember K7 and K19 are not cholangiocarcinoma-specific!
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social HCA vs HCC can be hard on biopsy! But B-catenin mutated should be treated similar to HCC per guidelines
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social
🩸CD34 can help you determine if you're in a lesion (usually increased)
🕸Retic, GS, and Glypican helpful for malignant vs not (mitoses, too)
🗺Map-like GS can be hard to interpret on biopsy!
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social Things to know before you do IHC in liver lesions:
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social Know your stain! Remember Arginase and HSA do not stain all hepatocellular neoplasm (even well-diff)
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social Reminds us that clones are important!
Liver examples: B-catenin, Ki67
#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social
The best IHC is
...
🥁
....
H&E!
💜💗

#USCAP2025 #liversky #pathsky

@ihcguy.bsky.social is super approachable! Reach out if you have questions!
🔑 Slide!
#USCAP2025 #liversky #pathsky

Dr Christine Sempoux
🥼Studies needed!
🗨Communication between pathologists and hepatologists so important!
#USCAP2025 #Liversky #pathsky

Dr Christine Sempoux
🗨PSVD is a term describing a pattern with multiple causes; is not synonymous with non-cirrhotic phtn!
🔬Histologic lesions described; standard terminology suggested
❔️We don't know significance of changes in absence of phtn
#USCAP2025 #Liversky #pathsky