Felix Franke

Felix Franke

@ffranke.bsky.social

Retina, Neuroscience, Engineering Timing in neural systems, Axons and their transmission speed Prof@Uni Basel / IOB

192 Followers 128 Following 3 Posts Joined Jan 2024
5 months ago
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In vivo single-cell gene editing using RNA electroporation reveals sequential adaptation of cortical neurons to excitatory-inhibitory imbalance The balance between excitatory and inhibitory neurotransmission is fundamental for normal brain function, yet the adaptation of individual neurons to disrupted excitatory-inhibitory balance is not wel...

Gene editing of single, targeted neurons in vivo is now feasible. We are proud to present our preprint for highly efficient single-cell electroporation using RNA. With @alex-fratzl.bsky.social, @munzlab.bsky.social, Botond Roska @iobswiss.bsky.social
#neuroskyence
www.biorxiv.org/content/10.1...

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6 months ago
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Thrilled to share that our work is now published in Science! ✨

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭

www.science.org/doi/10.1126/...

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7 months ago
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πŸ‘πŸ§  NEW: The human retina has its own built-in timing fix!
A Nature Neuroscience study led by @ethz.ch | BEL Lab, IOB Basel, @unibas.ch shows that photoreceptor signals – even those that travel farther – arrive in sync! >https://u.ethz.ch/S4DvU
#Retina #Neuroscience #Bioengineering #ETHZurich

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1 year ago

The answer: Photoreceptors need to connect to other neurons in your eye (via yet other neurons) and those can make the connection to your brain.

These neurons are called retinal ganglion cells, the one you see in the image.

But why a ring?

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1 year ago

Why does it look like a ring?

Because it is a ring. In the very center of your eye, you only have photoreceptors to detect light!

But photoreceptors do not connect to your brain.

So how to get the information from the photoreceptors out?

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1 year ago

You are currently using them to read this text!

The image basically shows how visual information about this letter here, yes this one (and this one, too!) is traveling from your eye to your brain.

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