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James Kane

@jameskane.blog.bsky.social

Software Engineer. Retro Computing. Genetic Genealogist. Fitness Enthusiast. TTRPG Gamer. Living the in the American Midwest.

339 Followers  |  359 Following  |  142 Posts  |  Joined: 31.08.2023  |  1.8418

Latest posts by jameskane.blog on Bluesky

First 3 week training block done for the Midwest Spartan Beast in September. Sore and slow compared to this time of year last year. The training plan calls for a rest day tomorrow fortunately.

20.07.2025 22:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Well the GoRuck Mackall has the same problem as the Rough Runners with my feet. The heel just doesn’t lock in correctly. Back to other options for rucking.

20.07.2025 00:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I have often said economics is only a science when you ignore psychology. Reliance on consumers being rational is one of its primary flaws.

06.07.2025 15:39 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image

#SavageRace placing obstacles before the starting line. Had a great time near Chicago on Saturday. Signing up again for next year.

30.06.2025 21:20 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Pulled out the GoRuck Rough Runners for a short ruck session this afternoon. Now I remember why they were pulled from rotation. They are great except the heals have hot spots that blister my ankles after more than a few minutes.

22.06.2025 23:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
New callable regions report generated from a short-read WGS BAM.  Summarizing the Y chromosome alignment characteristics.

New callable regions report generated from a short-read WGS BAM. Summarizing the Y chromosome alignment characteristics.

Finished rewriting the old histogram generator for plotting callable regions in a BAM. Now to create a module to uniquely fingerprint the source file to allow uploading anonymous stats for comparison.

github.com/JamesKane/De...

17.06.2025 00:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The first computer I used? An Apple IIc.

The first computer I owned? A Commodore 64.

11.06.2025 11:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Human Pangenome Reference Experiments Human Pangenome Reference Experiments - Setup A Pipeline

I collected some notes and early observations for aligning files to HPRC's 1.1 release of the human pan genome with vg giraffe. Mostly working on organizing a workflow for when someone with substantially more compute resources releases graphs based on Release 2.

jameskane.blog/genomics/202...

08.06.2025 20:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Heat map of global human biosamples in public repositories.  Showing a clear preference in geographic sampling of Europe and the United States.

Heat map of global human biosamples in public repositories. Showing a clear preference in geographic sampling of Europe and the United States.

Added a population heat map to #Decoding-Us, which is starting to work as the scripts backfill the geo positions for the public samples in the References page. This will incorporate the D2C samples that get added to the planned federated network. #CitizenScience

04.06.2025 21:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Messing around with vg giraffe and the older chm13+Y release. I think I have a viable workflow for short paired-end reads and projecting them back to a linear reference. Now to wait on the folks with the big iron to release a graph update that includes chm13v2.

31.05.2025 02:03 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It’s like these idiots failed economics 101.

28.05.2025 21:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Nobody wants a subscription service for a vehicle they paid more than $60k for.

28.05.2025 21:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
References

Piecing together a collection of #GeneticGenealogy relevant publications with their Impact Metrics and samples in ENA. If I can find the projects in this deluge of meta-data, I should be able to get it fully automatic and open for others to add papers by their DOI.

decoding-us.com/references

26.05.2025 20:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Decoding Us

Long weekend means there’s some time to get the Y and mtDNA trees loaded @ decoding-us.com. The views are ready but working on converting the final tree from YDNA Warehouse.

Then on to getting AT Protocol OAuth working, and publishing a few more APIs.

#GeneticGenealogy #CitizenScience #DecodingUs

24.05.2025 01:47 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Stupid Questions from Co-Workers:

Can't we just delete the Production Cloud Formation stack for an error that can simply be rolled back from?

18.05.2025 06:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Annoyed as hell. I wanted to get a new web app deployed this weekend, but because #cellcom is basically down. I can't receive the SMS messages for the 2-factor auth to finish configuration of the domain name.

17.05.2025 21:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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GitHub - JamesKane/DecodingUsTools: Various tools for BAM files Various tools for BAM files. Contribute to JamesKane/DecodingUsTools development by creating an account on GitHub.

Starting to extract tools that were part of YDNA Warehouse.

1) Coverage - a hybrid of samtools coverage and CallableLoci. Still need to add BED and histogram output.

2) mt and Y DNA haplogroup finder FTDNAs trees.

Should work with any hg38 aligned BAM.

github.com/JamesKane/De...

10.05.2025 00:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Those son of a bitches on Heard Island have been brought to heel.

08.05.2025 01:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
OSRIC 3 The 2006 retro-clone of first edition AD&D, rewritten and reorganized for 2025! OSRIC 3 is easier to learn, with more examples of play. This is the beginning of a new product line for Mythmere Games, ...

So… OSRIC 3.

PROs: Split into two volumes and smyth-sewn unlike my hard copy of OSRIC.

CONS: Landscape and I have two copies of original AD&D.

Need to think about this one for a while. #OSR.

www.backerkit.com/c/projects/m...

06.05.2025 21:26 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A movie I've watched more than six times.

(Gifs only, with Hard mode: no Star Wars, Star Trek, or LOTR)

30.04.2025 14:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This came out shortly after the OGL debacle. I don't think anyone foresaw WotC doing Creative Commons as part of that fallout.

I have things under CC for non-RPG stuff, but it certainly not for every creator.

30.04.2025 13:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Cypher System Open License - Monte Cook Games The Cypher System Open License (CSOL) allows publishers, gamers, and members of the public to freely create and publish tabletop […]

www.montecookgames.com/cypher-syste...

30.04.2025 12:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Dipshit does not realize the only manufacturing that will return is robotic. Sure there’s a handful of jobs to keep them running, but it will never be a major sync for laborers to find work much less a career.

29.04.2025 21:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Interesting question as Stellantis owns Chrysler, Dodge, Jeep and Ram. Are they foreign automakers now?

29.04.2025 20:38 β€” πŸ‘ 13    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Is Chrysler/Dodge/Jeep foreign or domestic now? They are owned by Stellantis after all.

29.04.2025 20:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Small maker raises prices to afford manufacturing in US, gets ZERO sales 🀑
YouTube video by Louis Rossmann Small maker raises prices to afford manufacturing in US, gets ZERO sales 🀑

@louisrossmann.bsky.social dropping some truth bombs.

youtu.be/Ri_ERbaTtgk?...

28.04.2025 17:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Wake us up if anything like that actually passes both houses.

25.04.2025 22:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Picked up a few physical items from this. The Kobolds have some great stuff for 5E.

25.04.2025 22:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Yet they couldn't see all those obvious signs before they elected him a second time...

24.04.2025 12:01 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Hmmm… had to add the Quiet Posters feed to start seeing folks that disappeared again.

22.04.2025 01:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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