Steph Cragg

Join us!

This Thanksgiving, we’re thankful for the scientists, researchers, and advocates driving progress in Parkinson’s research. 🍂🦃

Each idea tested, discovery shared, and partnership formed moves us closer to a future transformed by science.

Thank you for advancing understanding and hope.

Our multi-omic analysis of the primate striatum reveals heterogenous MSN organization across its rostro-caudal extent, new MSN subtypes, and subtype-specific disease enrichment. www.biorxiv.org/content/10.1...

Adenosine in the Brain: Recent Progress on Detection, Function, and Translation Although adenosine was identified in the brain many decades ago, our understanding of when, where, and how it functions has expanded rapidly in recent years, driven in part by innovative technological...

At #SfN25 in San Diego this week? #Adenosine fans, this one is for you! Catch Dr. Kathryn Todd at MIN40 | Room 6CR on Wednesday at 2:30 pm PST!

Want more? Dive deeper with the must-read review by the full group of speakers and chairs!

@stephcragg.bsky.social

We were thrilled to (mostly) meet in-person last week for the 3rd Annual Symposium of ASAP Collaboration for Team Cragg!

Thank you all for an inspiring meeting of science, sharing and #collaboration. We have built a great momentum, and we are ready for new discoveries in #Parkinsons research!

Abstract submissions are now OPEN for the Dopamine 2026 meeting!

Share your latest discoveries and join the global dopamine community in advancing the science of motivation, movement, and reward.

Submit here: dopaminesociety.org/abstracts/

#Dopamine2026

We are excited to present the shortlists for the 2025 Nature Awards for Inspiring Women in Science. Congratulations to the thirteen excellent candidates who made it to this year’s shortlist. Read more about the candidates and learn more about the award: go.nature.com/46nlAWy #WomeninStem

Oxford Professors Cragg and Walton celebrate publication of new book, The Handbook of Dopamine

We have an exciting new book to announce! www.dpag.ox.ac.uk/news/oxford-...

Dopamine Decoded: 5 Myths, 10 Facts What does dopamine actually do? A neuroscientist breaks down the science and clears up common misconceptions.

Dopamine Decoded: 5 Myths, 10 Facts | Psychology Today www.psychologytoday.com/us/blog/betw...

With yours truly 😊🧪👩🏼‍🔬

Lovely to hear you enjoyed it!!

Home - NeuroFrance 2025 Every two years, neuroscientists from all over France get together to share their research, discover new ideas and exchange views and opinions.

The Cragg lab is going to NeuroFrance 2025 in Montpellier!

Our very own PI Steph Cragg will give a plenary lecture on astrocytes, dopamine and acetylcholine, and lab members Simon Bossi and Lucille Duquenoy will present posters on their impressive work. Come say hi!

www.neurosciences.asso.fr/SN25/

Congratulations to Katherine Brimblecombe from Cragg Lab!

Her study on L-type calcium channels and striatal dopamine release (doi.org/10.1111/ejn....) is among the most widely read papers published by EJN in 2023!

A fantastic recognition of her work within the community!

@stephcragg.bsky.social

🎉 The Cragg lab is hiring 🎉 Are you interest in striatal neurobiology and have relevant lab experience? Join us as an MRC-funded Research Assistant at the University of Oxford. Deadline is noon (UK time) on May 2nd.

@stephcragg.bsky.social @oxforddpag.bsky.social

my.corehr.com/pls/uoxrecru...

US scientists create most comprehensive circuit diagram of mammalian brain 3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring The most comprehensive circuit diagram of neurons in a mammalian brain has been created by scientists, providing groundbreaking insights into the mystery of how the brain works. The map is of a speck of a mouse’s visual cortex, smaller than a grain of sand, and traces the structure of 84,000 neurons linked by half a billion synapses and approximately 5.4km of neuronal wiring. The 3D reconstruction of the cubic millimetre of brain is helping uncover how the brain is organised and how different cell types work together, and could have implications for the understanding of intelligence, consciousness and neuronal conditions such as Alzheimer’s, Parkinson’s, autism and schizophrenia. Continue reading...

US scientists create most comprehensive circuit diagram of mammalian brain

Last week, CRN members met in Phoenix, Arizona for ASAP's 2025 CRN Collaborative Meeting 🥳

It was full of collaboration and enlightening conversations. Thank you to all who attended and made this meeting a success!

Learn more about the CRN here: bit.ly/41MnIod

#ParkinsonsResearch

Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons Abstract. Corticostriatal regulation of striatal dopamine (DA) transmission has long been postulated, but ionotropic glutamate receptors have not been loca

Great, as we saw in mouse striatum. academic.oup.com/cercor/artic...

Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons Abstract. Corticostriatal regulation of striatal dopamine (DA) transmission has long been postulated, but ionotropic glutamate receptors have not been loca

In line with our 2016 study here! academic.oup.com/cercor/artic...

New study from the lab is out revisiting old friends/foes #dopamine and #acetylcholine 🧠 @natureneuro.bsky.social ! Congrats and thanks to all the team!
#openscience
@asapresearch.bsky.social @craggasap.bsky.social
@oxforddpag.bsky.social

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...

Remember, EuropePMC is actually better than #PubMed because it includes ALL preprints in search results, not just those including NIH-funded research.

europepmc.org

Boston, MA Location: Massachusetts State House 24 Beacon St, Boston, MA, United States Address: 24 Beacon St., Boston, MA, 02133 Time: 12-4 PM Important information: Please do not fully block the sidewalk, st…

Stand up for Science, on March 7th, in Boston. Please help spread this widely.

❤️

Thanks Johannes! I like your analogy! 🧽

Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes Nature Communications - Astrocytes perform intriguing roles in neural circuits. Here, the authors show that in striatum, astrocytes adopt a satellite-like proximity to cholinergic interneurons,...

Excited to share our new publication out today in Nature Communications! Congrats to the team! @craggasap.bsky.social
#dopamine #astrocytes #acetylcholine #openscience Supported by @ukri.org and @asapresearch.bsky.social
rdcu.be/d0Knj

Welcome! I'm posting here mostly about science and our research. Today's new publication 😊 to follow! #openscience #neuroscience #dopamine #astrocytes

Program - MMiN

A great program announced for May’s meeting for Monitoring Molecules in Neuroscience #MMiN2024. Come and join us!
monitoringmolecules.org/program/

An axonal brake on striatal dopamine output by cholinergic interneurons https://www.biorxiv.org/content/10.1101/2024.02.17.580796v1 Depolarisation of distal axons is necessary for neurons to translate somatic action potentials into

An axonal brake on striatal dopamine output by cholinergic interneurons https://www.biorxiv.org/content/10.1101/2024.02.17.580796v1

This Team Tuesday highlights Team Cragg. Read about the team's interactive platform that allows users to view and access spatial transcriptomic and TRAP-seq data, collected from aged and alpha-synuclein overexpressing mice. 🧪📈 🧠

parkinsonsroadmap.org/research-net...