Ariel Levine

Ariel Levine

@ariellevine.bsky.social

Spinal cord and motor control scientist; PI at NINDS

1,826 Followers 1,132 Following 165 Posts Joined Sep 2023
3 hours ago
YouTube
Impressive jump of the fox to hunt a mouse under the snow #animals #nature #fox #wildlife YouTube video by window on nature

m.youtube.com/shorts/D44-G...

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3 hours ago
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#Wildlife 32 #jerboa and #snake #dakrouri #shorts YouTube video by Dakrouri

m.youtube.com/shorts/l1kne...

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3 hours ago
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Jumping around so cute and adorable rabbit YouTube video by Brown Rabbit

m.youtube.com/shorts/2ruJx...

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3 hours ago
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Impalas Leap Across The Road YouTube video by The Dodo

m.youtube.com/watch?v=lbQg...

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3 hours ago
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cute cat jumping into the wall hole YouTube video by OuR CeLeBrItIeS

m.youtube.com/shorts/NCZd1...

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3 hours ago
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Dog Jumps Joyfully Through Field of Tall Grass || ViralHog YouTube video by ViralHog

m.youtube.com/shorts/1N7LR...

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3 hours ago
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Jumping Bobcat Slow Motion | Planet Earth II YouTube video by BAMBI

To celebrate our new pre-print from @fabricionicola.bsky.social, a few of my favorite animal jumps…

www.biorxiv.org/content/10.6...

youtu.be/OX9GTi-wQ6I

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3 hours ago

Check out the newest work from our, from Fabricio Nicola @fabricionicola.bsky.social on mouse jumping and spinal cell types.

Excellent collab with @vulcnethologist.bsky.social

www.biorxiv.org/content/10.6...

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1 week ago

Love seeing the convergence of cell types and systems thinking!

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1 week ago
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How does the brain generalize past experiences without confusing memories? 🧠

Our lab's newest preprint reveals a fundamental division of labor between the cortex and cerebellum that solves this problem. (Check out the cortex-cerebellum video below! 👇) 🧵

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1 month ago

Want to come do a postdoc with us?

We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!

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1 month ago

I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

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1 month ago
ESFS: A Noise-Resilient Framework for Feature Selection and Marker Gene Discovery in Single-Cell Transcriptomics Single-cell RNA sequencing (scRNA-seq) has transformed our ability to resolve cellular heterogeneity, but extracting meaningful signals remains challenging due to technical noise, batch effects, and the limitations of current feature selection methods. We present Entropy Sorting Feature Selection (ESFS), a modular, user-friendly framework that captures multivariate gene expression relationships without imputation or denoising via latent spaces. Across diverse datasets, ESFS improves interpretability and reveals biology missed by standard workflows: identifying coherent developmental programs in eight independent human embryo datasets without batch integration; resolving spatial gene expression in mouse colon obscured by conventional analyses; distinguishing shared and tumour-specific microenvironments in glioblastoma; and disambiguating spatial, temporal, and neurogenic programs in the developing mouse neural tube. By operating in gene expression space, ESFS produces interpretable, biologically meaningful outputs while reducing artefacts introduced by feature extraction. These results position ESFS as a powerful means to uncover relevant molecular signatures in noisy, high-dimensional transcriptomics data. ### Competing Interest Statement The authors have declared no competing interest. Cancer Research UK, CC001051 Medical Research Council, https://ror.org/03x94j517, CC001051 Wellcome Trust, CC001051 Wellcome Trust, 220379/D/20/Z European Molecular Biology Organization, 792-2021 UK Research and Innovation, EP/X031225/1

Our latest: A gene selection method for single-cell RNA-seq that identifies developmental & spatial patterns missed by other analysis pipelines

ESFS: A Noise-Resilient Framework for Feature Selection and Marker Gene Discovery in Single-Cell Transcriptomics | bioRxiv www.biorxiv.org/content/10.6...

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1 month ago

Thank you, Remi!

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2 months ago

Thank you 😊

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2 months ago
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Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.”

A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.

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2 months ago

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

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2 months ago

Thanks, Rune!

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2 months ago

Thank you :)

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2 months ago

Thank you, Helen!

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2 months ago

Thank you!

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2 months ago

Thank you, Andreas!

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2 months ago
Preview
Ontogeny of the spinal cord dorsal horn The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...

Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org

This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.

www.science.org/doi/10.1126/...

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2 months ago

Of course! It’s the reading room in the original Shakespeare and co bookstore in Paris. And yes, it is magical

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2 months ago
A corner of a laptop screen in a room filled with old books and comfy well-worn furniture - Shakespeare and Co bookstore in Paris

Welp, this has been a tough year, but finishing it up working on a paper I’m *very* excited about, in a place like this… that’s really nice

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3 months ago

Congratulations!!

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3 months ago

Join us for Fall 2026. In our group, you can run studies from human behavior and neuroimaging, to large-scale NHP ephys, and join them up with a robust computational foundation. Bonus: you can help build the reading list.

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3 months ago

First paper from the lab is now online
@natneuro.nature.com !
We mapped injury induced enhancers in the mouse CNS and decoded their sequence architecture. Little 🧵 rdcu.be/eSQi1

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3 months ago

Hello 🇫🇷

I’ll be doing a mini-sabbatical in the lab of the amazing @clairewyart.bsky.social at the ICM in Paris. If you study motor control, spinal cord biology, evo/devo of behavior, let me know if you’d like to connect!

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3 months ago

Oh yeah. In the lab, we’ve discussed every common definition because we study gap crossing jumps and the propulsive phase is likely the closest. I believe in frogs it is truly ballistic but mammals can tune it a bit

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