Princeton Neuroscience Institute

O’Shea awarded a NJ ACTS translational science fellowship MD/PhD student Callan O’Shea, a member of the Princeton University Department of Molecular Biology (MOL), is the newest recipient of the New Jersey Alliance for Clinical and Translational Science Awar...

Congrats🥂 to Callan O’Shea, a MolBio M.D./Ph.D student and newest recipient of the New Jersey Alliance for Clinical and Translational Science Award (NJ ACTS) T32 Fellowship. O'Shea is advised by associated faculty member Sam Wang. molbio.princeton.edu/news/2025/os...

How FlyWire is redefining Drosophila research, one year in Nine Drosophila researchers share how the connectome transformed the field and what additional new tools they would like to see.

To celebrate the first anniversary of the release of FlyWire, we asked nine neuroscientists to share how they are using connectome data in their research and what they hope is in store for the future of fly connectomics.

By @franciscorr25.bsky.social

#neuroskyence

bit.ly/3Wx5nt3

Princeton Engineering - Christina Kim, an expert in the brain and behavior, named Freeman Hrabowski Scholar by Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) has named Christina K. Kim a Freeman Hrabowski Scholar, supporting her research on how modifications in brain

Congratulations to PNI's @tinakim-neuro.bsky.social on being named a @hhmi.org Freeman Hrabowski Scholar, which will support her research on how modifications in brain cells result in long-lasting changes in behavior!!
engineering.princeton.edu/news/2025/10...

We're Hiring. Assistant professor in the area of human cognitive neuroscience. Princeton University shield logo subbrand lockup with the Princeton Neuroscience Institute (PNI) and Dept of Psychology logos. Background photo = PNI and psychology building (Peretsman Scully Hall).

We're hiring! The Princeton Neuroscience Institute and Department of Psychology invite applications for a joint hire Assistant Professor in human cognitive neuroscience 🧠

Review of applications begin Oct 15. More details here: puwebp.princeton.edu/AcadHire/app...

TITLE TEXT: "CV Starr Postdoctoral Fellowship Opportunity" BODY TEXT: "The Princeton Neuroscience Institute invites collaborative scientists with exceptional skills and potential to apply for the 3-year CV Starr Fellowship program, which provides an attractive salary and a modest research budget. Applications due October 10, 2025."

⏰ Deadline approaching — apply for the PNI C.V. Starr Fellowship by Oct 10!

🧠 Up to 3 years of salary and research support, along with world-class faculty mentorship and facilities.

🔗 Learn more: pni.princeton.edu/apply/postdo...

When a rat makes up its mind, these neuroscientists know Scientists can now freeze-frame the exact moment an animal makes up their mind and commits to a choice — simply by looking at their brain activity

With the help of AI, Princeton’s @thomas-zhihao-luo.bsky.social and @carlosbrody.bsky.social can now pinpoint the exact moment a rat makes up its mind — just by reading its brain activity 🧠🐀
pni.princeton.edu/news/2025/wh...

#NeuroJobs

#NeuroJobs

Love how this project came together with the amazing @endoeartha.bsky.social ! Have you wondered about the role that testosterone plays in the ability to re-pattern social behavior when you are at home in your "territory" vs away? We have answers for you...

Very excited and proud to share my postdoctoral research with @neurrriot.bsky.social looking at the context-specific encoding of social behavior 💃🕺 in hormone-sensitive, large-scale brain networks in mice!

www.biorxiv.org/content/10.1...

#neuroskyence #compneurosky 🧪
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TITLE TEXT: "CV Starr Postdoctoral Fellowship Opportunity" BODY TEXT: "The Princeton Neuroscience Institute invites collaborative scientists with exceptional skills and potential to apply for the 3-year CV Starr Fellowship program, which provides an attractive salary and a modest research budget. Applications due October 10, 2025."

Looking for a neuroscience postdoc opportunity with competitive salary + research funds? Apply for PNI's C.V. Starr Fellowship, which offers collaboration, mentorship, and up to 3 years of support!

Applications due Oct 10.

Learn more 🔗 pni.princeton.edu/apply/postdo...

Thank you @nancyrmack.bsky.social and @princetonneuro.bsky.social for a great explainer about our paper!

pni.princeton.edu/news/2025/wh...

What happens in your brain when you make up your mind?

Postdoc (soon faculty at U. of Utah) @thomas-zhihao-luo.bsky.social and ex-grad student (now Shanahan Fellow at Allen Institute) @timkimd.bsky.social have some answers in this new paper out in Nature!

www.nature.com/articles/s41...

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Opinion | Trump Is Defunding Medical Research. It Could Cost You Your Life. - The New York Times In the Opinion video above, meet the scientists who are trying to save your life — and the lives of your children and grandchildren.

In the @nytopinion.nytimes.com, PNI’s @sebastianseung.bsky.social warns federal research cuts endanger Americans’ health.
"Think about Alzheimer's Disease and Parkinson's disease. The dollar cost of these are huge. And the emotional costs are even huger. Can we wait?" www.nytimes.com/2025/08/24/o...

Transitions in dynamical regime and neural mode during perceptual decisions - Nature Simultaneous recordings were made of hundreds of neurons in the rat frontal cortex and striatum, showing that decision commitment involves a rapid, coordinated transition in dynamical regime and neura...

How does the brain decide? 🧠

Our new @nature.com paper shows that neural activity switches from an 'evidence gathering' to a 'commitment' state at a precise moment we call nTc.

After nTc, new evidence is ignored, revealing a neural marker for the instant when the mind is made up.

rdcu.be/eGUrv

Worms help untangle brain structure/function mystery The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.

Two preprints from the lab of PNI's @andrewleifer.bsky.social provide new insights into the longstanding challenge of how brain wiring relates to brain activity 🧠 www.thetransmitter.org/connectome/w...

Neuroscientist Christina Kim ’11 Is Mapping the Brain for Better Therapies Stuntman Kent De Mond ’07 is on fire; Endowment tax fallout; Pilot Michael Holl ’03 trains Qataris

Originally an aspiring cellist from Huntsville, AL, @tinakim-neuro.bsky.social returns to Princeton as a professor of neuroscience & bioengineering, where she builds new tools to study the brain and advance treatments for mental health:

Dr. Annegret Falkner - One Mind “Protecting mood and decision-making during hormonal shifts—paving the way for next-generation, targeted hormone treatments without the side effects.” Dr. Annegret Falkner’s research maps how social…

Congrats to PNI's @neurrriot.bsky.social on earning a 2025 @onemindorg.bsky.social Rising Star Award 🌟

The funds will support her lab's work on protecting mood and decision-making during hormonal shifts, which may pave the way for targeted hormone treatments 🧠

Could a baby’s still-growing brain help set the stage for learning language? A new study from the lab of Princeton's Asif Ghazanfar finds surprising clues from chatty monkeys who share the power of babble.

📰: pni.princeton.edu/news/2025/ba...

TITLE TEXT: "CV Starr Postdoctoral Fellowship Opportunity" BODY TEXT: "The Princeton Neuroscience Institute invites collaborative scientists with exceptional skills and potential to apply for the 3-year CV Starr Fellowship program, which provides an attractive salary and a modest research budget. Applications due October 10, 2025."

🚨 Applications are open! The Princeton Neuroscience Institute invites exceptional postdoctoral researchers to apply for our CV Starr Fellowship, which provides up to 3 years of support plus research funds 🌠

🗓️ Deadline: Oct 10, 2025
🔗 More info: pni.princeton.edu/apply/postdo...

Last week, the International Brain Laboratory released a comprehensive activity map of the rodent brain during decision-making, enabling researchers to "test new ideas in a really easy and powerful way," says neuroscientist @predictivebrain.bsky.social.

By @claudia-lopez.bsky.social

bit.ly/4mhqMRO

This is figure 2, which shows brain-wide recordings during behaviour.

The International Brain Laboratory presents in Nature a brain-wide electrophysiological map that represents a resource for understanding how computations distributed across and within brain areas drive behaviour. go.nature.com/4nnnmhg 🧪 🧠📈

Excited to share our new preprint on the brain-wide organization of intrinsic timescales at single neuron resolution. Work w/ @roxana-zeraati.bsky.social, @intlbrainlab.bsky.social, Anna Levina, @engeltatiana.bsky.social : www.biorxiv.org/content/10.1...

New work with @shiyanliang.bsky.social‬, @roxana-zeraati.bsky.social, @intlbrainlab.bsky.social, Anna Levina. We uncover the principles that organize single-neuron timescales across the entire brain, unifying regional specialization with universal brain-wide dynamics: www.biorxiv.org/content/10.1...

Everything everywhere all at once: Decision-making signals engage entire brain The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

The mouse brain lights up during decision making, showing widespread activity across both predictable as well as unexpected areas.

By @claudia-lopez.bsky.social

#neuroskyence

www.thetransmitter.org/decision-mak...

First map of mammal brain activity may have shown intuition in action Scientists have mapped the activity that takes place across a mouse's entire brain as it decides how to complete a task - and the results could explain the origin of our gut feelings

The first complete activity map of a mammalian brain has revealed unprecedented insights into how decisions are made – and may even hint at the roots of intuition.

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬:
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

Princeton’s @ilanawitten.bsky.social, @engeltatiana.bsky.social, and @jpillowtime.bsky.social have created the first-ever brain-wide activity map during decision making in mice as part of an international group effort known as the @intlbrainlab.bsky.social.

🔗 pni.princeton.edu/news/2025/fi...

A complete brain-wide activity map at single-cell resolution has been revealed for the first time.

Researchers recorded from 650,000+ neurons across 279 brain areas to track decision-making in mice.

Read the story:
🔗 www.sainsburywellcome.org/web/research...

We're Hiring. Assistant professor in the area of human cognitive neuroscience. Princeton University shield logo subbrand lockup with the Princeton Neuroscience Institute (PNI) and Dept of Psychology logos. Background photo = PNI and psychology building (Peretsman Scully Hall).

We're hiring! The Princeton Neuroscience Institute and Department of Psychology invite applications for a joint hire Assistant Professor in human cognitive neuroscience 🧠

Review of applications begin Oct 15. More details here: puwebp.princeton.edu/AcadHire/app...