International Brain Laboratory

Infinite hidden Markov models can dissect the complexities of learning - Nature Neuroscience Bruijns et al. present a modeling tool that enables the tracking of learning dynamics across subjects to reveal how behaviors emerge and adapt. Applying the tool to a decision-making task in mice unco...

New in Nature Neuroscience: We developed a flexible model that reveals how animals learn tasks—uncovering stages, sudden insights, and gradual improvements unique to each animal.
Learning isn't monotonic, and our model captures that complexity 🐭📊
www.nature.com/articles/s41...

Screenshots of Lightning Pose 3D app

🎉 Excited to announce Lightning Pose 3D!

A complete redesign of our app with powerful new features: calibration-aware labeling for multiview data, state-of-the-art multiview transformer models for training & inference, an interactive video viewer, and continued support for single-view projects.

The Pre-COSYNE Brainhack 2026 Everything you need to know about the Pre-COSYNE Brainhack 2026 in Lisbon, Portugal.

This year’s Brainhack draws inspiration from CON²PHYS: same dataset, same questions, many truths? Expect hacking sessions, mini-presentations, discussions on reproducibility and a welcoming environment for all skill levels. Apply now (limited spots): pre-cosyne-brainhack.github.io/hackathon202...

Pre-COSYNE Brainhack 2026 The 2026 edition of the Pre-COSYNE Brainhack in Lisbon, Portugal.

Pre-COSYNE Brainhack 2026 – Join Us in Lisbon!
March 10–11, 2026 • Lisbon, Portugal

pre-cosyne-brainhack.github.io/hackathon2026/

Kick off COSYNE week with two days of hands-on, team-based hacking around real electrophysiology data, open tools, and reproducible workflows. #brainhack #cosyne2026

Apply to work with the IBL Core — International Brain Laboratory

We can help with your Neuropixels recordings, multiphoton imaging, data processing, visualisation, management, and more. Applications are due November 1st! www.internationalbrainlab.com/ibl-core-apply

Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply

These papers show what collaborative science can achieve: standardized methods, open data, and shared tools driving new insights into the brain. The next discoveries are ahead. Come join us!
#Neuroscience #OpenScience #Collaboration

Apply to work with the IBL Core — International Brain Laboratory

If you have a project idea (experiment or theory!) please apply to become an IBL partner: internationalbrainlab.com/ibl-core-apply +

IBL’s next phase is to work with new partners. We have funding to support groups anywhere in the world to do new large-scale projects. We can help you with Neuropixel recordings, multiphoton imaging, data processing, visualisation, data management, and more. +

A common computational and neural anomaly across mouse models of autism - Nature Neuroscience Noel et al. show aberrant updating of expectations in three distinct mouse models of autism spectrum disorder. Brain-wide neurophysiology data suggest this stems from excess units encoding deviations ...

These studies are just the beginning. The same infrastructure is now powering many new projects, such as this study by Jean-Paul Noel & colleagues on autism:
🧠 www.nature.com/articles/s41... +

We discovered that decisions arise from many brain areas working together—including regions previously overlooked by scientists—to integrate current evidence with beliefs from prior choices. We establish large-scale, collaborative science as a tool to unlock the brain’s secrets +

Data — International Brain Laboratory

Twenty labs collaborated to build:
- Recordings from the entire mouse brain during a behavioral task (data.internationalbrainlab.org)
- Open and reproducible workflows and data standards
- An organisational structure enabling scientific discovery among distributed groups +

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬:
🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0
🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

A conversation with research software engineers at the International Brain Laboratory Open-source software is the lifeblood of many modern research projects, allowing researchers to push boundaries, build collaborations, and work transparently. The International Brain Laboratory (IBL),...

Hear directly from our amazing team members: A conversation with research software engineers at the International Brain Laboratory: Patterns www.cell.com/patterns/ful...

Excited to announce the Foundation Models for the Brain and Body workshop at #NeurIPS2025! 🧠📈 🧪

We invite short papers or interactive demos on AI for neural, physiological or behavioral data.

Submit by Aug 22 👉 brainbodyfm-workshop.github.io

Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social !

We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠

Another step toward a foundation model of the mouse brain: "Neural Encoding and Decoding at Scale (NEDS)"

Trained on neural and behavioral data from 70+ mice, NEDS achieves state-of-the-art prediction of behavior (decoding) and neural responses (encoding) on held-out animals. 🐀

Ported over from X!

What will a foundation model for the brain look like? 🧠

We argue that it must be able to solve a diverse set of tasks across multiple brain regions and animals.

Check out our NeurIPS paper which introduces a multi-region, multi-animal, multi-task model arxiv.org/abs/2407.14668

Come see us at #sfn #sfn2023 #sfn23 sites.google.com/internationa...

Neuropixels insertions shown on a mouse brain

Going to SfN this year? Join us for a workshop on how to use the IBL Brainwide Map dataset to test your own hypotheses! For more information and to register, visit internationalbrainlab.org/sfn2023 #Neuroscience #compneuro #sfn2023