Andy Wolfe

In Game-Changing Climate Rollback, E.P.A. Aims to Kill a Bedrock Scientific Finding

www.nytimes.com/2025/07/29/c...

Exciting work!

25 Colleges. One University.

@cuny.edu Research in Focus looks at the work of Hunter College’s Climatologist and Professor of Geography and Environmental Science, William Solecki, who shows how we can design our public spaces to mitigate global warming. Read about it here: www.cuny.edu/news/resilie...

Congratulations and bon voyage to Hunter College alumni Sajida Ahmed, Alison Juray, Andrew Loka, and Alp Doymaz, who will be traveling all over the world during the 2025 - 2026 academic year through the Fulbright Program! #HunterPride hunter.cuny.edu/news/four-fr...

Excited to share our recent work published in PNAS last week uncovering the molecular mechanisms of PARP inhibitor resistance in BRCA2-deficient metastatic castration-resistant prostate cancer (mCRPC). Check out our manuscript!

Wolfe Lab at Hunter College group photo Spring 2025

Our amazing lab team, Spring 2025! A huge congratulations to the lab members about to earn their undergraduate degree, finish their postbaccalaureate program, begin graduate school, and begin medical school.

Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine | PNAS RAS is the most frequently mutated oncogene in cancer. RAS proteins show high sequence similarities in their G-domains but are significantly differ...

Very excited that this work was published in PNAS today!
www.pnas.org/doi/10.1073/...

Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1. Zhu Q, Yaggi MF, Jork N, Jessen HJ, and Diver MM. Nature Communications. Published online March 20, 2025.

Huge congratulations to Dr. Melinda Diver and her lab on the publication of this outstanding new study, "Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1" in the journal Nature Communications today!
www.nature.com/articles/s41...

The RNA-binding protein IMP2 reads m6A modifications to regulate target RNAs. When IMP2 changes, the many RNAs that it regulates change too, like a spider vibrating the strands of its web.

I am thrilled that our review about the RNA-binding protein IMP2 was published today! Congratulations to my co-authors Jessica Das, Ottavia Busia-Bourdain, and Khizr Khan.
doi.org/10.3390/ijms...

Nonopioid drug for acute pain wins FDA approval Ongoing trials will reveal whether suzetrigine is also effective against chronic pain

A long-awaited nonopioid pain drug has won approval from the U.S. Food and Drug Administration (FDA) to treat moderate to severe short-term pain.

KRAS Oncoprotein Signaling in Cancer | NEJM Recent studies provide new insights into signaling by mutant KRAS, inhibitors of which have provided modest benefits for patients.

Recent studies provide new insights into signaling by mutant KRAS, inhibitors of which have provided modest benefits for patients. Learn more in a new Clinical Implications of Basic Research article: nej.md/4aia1Bv

#MedSky #Oncology

A new post in Science Careers for our open-rank faculty search at the Hunter College Dept of Biological Sciences: jobs.sciencecareers.org/job/668588/o...

It's been a delight to be a Mentor to a Postbac Scholar in Damon Runyon SPARK this year. College seniors interested in paid full time cancer research next year - I encourage you to apply to SPARK. @damonrunyon.org damonrunyon.org/for-scientists/application-guidelines/research

Do you love science and want research experience before your next step? NY-RaMP is a 1 year paid opportunity for recent college graduates to do research in my lab or another lab at Hunter College. Learn more at a free webinar on Wed Dec 11 at 3 PM EST nyramp.org/webinars

Cancer researchers: Are you a postdoc ready to launch your own lab? Or an Assistant/Associate/Full Professor seeking a change of scene? The Biological Sciences dept at Hunter College in New York City is hiring! Apply to our new open rank faculty search: bit.ly/huntercollegebiology

Members of the Wolfe lab in Fall 2024.

What an amazing team!