Patrick van der Wel

[Admin] Liebe alle, @realscientists.de macht eine kleine Pause. In der Zwischenzeit suchen wir immer neue Wissenschaftler*innen, die eine Woche lang unseren Account übernehmen möchten. Wenn ihr Interesse habt, meldet euch unter: dasistsciencetwitter@gmail.com.

Biological Laboratory | LEGO® Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...

Curious how bad having the "wrong" wavelength of light, in the more energetic direction is, in a photochemical reaction? In a lot of reactions, with blue LEDs you're not hitting the maximum absorption of the system which falls into the UV, but more a shoulder. What happens instead if you (1/n)

Physical mechanisms of nanoparticle–membrane interactions: A coarse-grained study Nanoparticles are promising drug carriers for targeted therapies, diagnostic imaging, and advanced vaccines. However, their clinical translation is limited by c

We uncover the physical mechanisms governing nanoparticle–membrane interactions using coarse-grained simulations, mapping distinct regimes from adhesion to wrapping. A step toward predictive design rules for nanomedicine & adaptive materials

pubs.aip.org/aip/jcp/arti...

Also here!

Senior R&D Technician NMR/LC(MS) Dow, Terneuzen, the Netherlands corporate.dow.com/en-us/career... #NMRjobs #NMRchat 🧲

(in case you’re interested: the first paper from 2011 is here: doi.org/10.1021/ja11... and the most recent HD related paper is from 2025: doi.org/10.1002/chem... )

.. Multiple foundations from across the world have supported us, ensuring that this research could continue all these years.

In general, foundations, patients, friends and families play a key role in rare disease research - both for funding and advocacy. Thank you! @rarediseaseday.bsky.social

... which continues to this day. I hope we can continue to contribute our puzzle pieces to the challenging puzzle of understanding this disorder. For our research program the support of disease-focused foundations has been instrumental, especially in recent years.

Homepage Raising awareness for patients, families and carers around the world that are affected by rare diseases.

Once again… Feb 28 is Rare Diseases Day ( www.rarediseaseday.org ). A bit over 15 years ago, my lab got involved in research into the mechanisms behind one such disease: #huntingtonsdisease. Indeed, almost exactly 15 years ago (March 2011) we published our first article from this research line …

Phew… “Application submitted”.

Rare Disease Day 2026: Diverse community, common challenges - EveryONE This blog was prepared and written by PLOS One Associate Editor Alejandro Torrado Pacheco. Since its inception in 2008, Rare Disease Day is observed…

For #RareDiseaseDay, @plosone.org Academic Editors share their thoughts on the difficulty in obtaining diagnoses for rare disorders, the significant hurdle this poses to both clinical care and scientific understanding, and the importance of equitable access to scientific knowledge.

“It’s Rare Disease Day!” with the Rare Disease Day hand logo and the website” The background is a blue and purple gradient.

🌍 It’s #RareDiseaseDay 2026! 💜

Today we stand with the 300 million people living with a rare disease. Together, we’re showing our colours, raising awareness, and inspiring change by talking about what equity means to us.

👉 Read more: https://go.rarediseaseday.org/NEWS

Photo‐Modulated Proton Transport in Merocyanine Metastable‐State Photoacid Based Polymers The covalent incorporation of merocyanine metastable-state photoacid into soft polymers imparts conductivity to otherwise insulating matrices, allowing light-triggered control of charge and structure...

Check out our latest publication in Small, where we show that proton transport in polymeric films can be controlled using light!💡
onlinelibrary.wiley.com/doi/10.1002/...

Would you like to study membrane organization, dynamics, and cell death? 🧬 Check out the García-Sáez Group ( @office-garcia.bsky.social , @mpibp.bsky.social )

🗓 Application deadline: March 11 👉 imprs-cbp.mpg.de/call-for-app...

#imprs_cbp #membranebiophysics #apoptosis

Slovenly sentry tends to his gun under watchful eye of his dog. Thanks to recent cleaning, we can also see more alert sentry walking on wall behind him. As painted by Carel Fabritius of Delft, whose day is today.

Photograph of David Waldeck - in the background is the University of Pittsburgh's Cathedral of Learning

I share the sad news that Prof. David H. Waldeck passed away after a battle with cancer. Dave was an extraordinarily creative scientist, a devoted educator, and to all of us a friend, mentor, and leader.

He will be deeply missed

#chemsky #chemchat

#sketchchemistry shenanigans

Orbital parking lots

#chemsky #chemchat

@cenmag.bsky.social

Remembering Rob Schurko. MagLab’s NMR Director described as extraordinary leader, first-rate scholar, and remarkable person.

Remembering Rob Schurko. MagLab’s NMR Director described as extraordinary leader, first-rate scholar, and remarkable person. nationalmaglab.org/news-events/...

#ChemSky

I don't promote all our papers on here...like they are ALL AWESOME (of course they are, I wrote them, and you should be honoured to have access to my GREAT THOUGHTS) but this one is a bit special. And has broad implications.

doi.org/10.26434/che...

⚗️📜🧵

For the #chemsky peptide chemists out there. New preprint dropping next week. With this banger of a sentence:

Herein, we provide the extraordinary evidence demonstrating that [COOL-ASS APPROACH] may prove to be the most important advance in peptide synthesis since the development of Fmoc chemistry.

My quote of the day

Science is the search for truth, that is the effort to understand the world: it involves the rejection of bias, of dogma, of revelation, but not the rejection of morality.

Linus Pauling

Captain Haddock looking very frazzled, saying, “What a week, huh?” Tintin leans into the frame and says, “Captain, it’s Wednesday.” Snowy aka Milou is very excited about the drink he has found.

Zondagskinderen De geschiedenis beukt op Europa's deur.

De geschiedenis beukt op Europa's deur. Na tachtig jaar vrede en de EU als geslaagd project zijn oorlog en chaos de nieuwe werkelijkheid. We kunnen geen zondagskinderen meer zijn. Worden we ontnuchterde maandagskinderen? pgkroeger.substack.com/p/zondagskin...

- writing clearly is not something we can bypass. To a great extent tweaking language is part of the work.
- same for designing great figures.

No easy answers here and these are all things we are going to have to address

the benefit from writing the paper is not having a 30-page paper as a result

the benefit is the thinking that goes along with writing the paper — that is part of writing the paper.

If all that's done is the pre-analysis plan and the analysis then that limits the new thinking

Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...

FEBS Press In this issue, Elmaleh et al. demonstrate that the E425K mutation in DNAJC7, associated with amyotrophic lateral sclerosis, selectively abolishes one of a co-chaperone's dual functions. High-resoluti...

Holding but not folding: How a single charge flip uncouples the DNAJC7-Hsp70 relay in amyotrophic lateral sclerosis

febs.onlinelibrary.wiley.com/doi/10.1111/...

Materials Engineer, Failure Analyst - NMR Specialist - Jobs - Careers at Apple Apply for a Materials Engineer, Failure Analyst - NMR Specialist job at Apple. Read about the role and find out if it’s right for you.

Materials Engineer, Failure Analyst - NMR Specialist (organic, polymeric and other novel material) Apple, Cupertino, California, United States jobs.apple.com/en-us/detail... #NMRjobs #NMRchat 🧲

Photo of Lynmarie Thompson, the president of the Biophysical Society, presenting a plaque to Sarah Veatch for winning the 2026 Agnes Pockels Award.

Of course, I am over the moon with happiness that @veatchlab.bsky.social won the 2026 Agnes Pockels Award from the @biophysicalsoc.bsky.social. Moreover, TWO students in Sarah's lab won poster awards at the BPS Meeting! What a year for the Veatch Lab! #bps2026