Thomas R. Cox

Calling all ECRs in cancer and metastasis research. Don't forget to register for the upcoming ECR Virtual Symposium in November (FREE for MRS members). More details here metastasis-research.org/2025/08/06/2...

Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Evolutionary paths towards metastasis - Nature Reviews Cancer In this Perspective, Kamila Naxerova discusses how genetic analyses of primary tumours and matched metastases can distinguish between competing metastasis evolution models, arguing that further insigh...

Evolutionary paths towards metastasis
www.nature.com/articles/s41...

CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis - Cell Research Cell Research - CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis

🧠 Neuro-immunology is reshaping how we understand the brain - across many diseases, including #cancer

In this research highlight 🧪🔬 we discuss a new study in #Nature by Remsik, Boire et al showing how IFNγ-activated immune cells in the CNS, incl DCs, help constrain leptomeningeal #metastasis

Congrats! 🥳

How your brain controls ageing — and why zombie cells could be key Research is revealing the cellular mechanisms that link mental well-being and longevity.

Nature reports on how scientists are working to decipher the precise mechanisms that connect the brain to processes associated with ageing. #medsky 🧪

Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

1/Meet the MRS ECLC Chairs! Dr. Thomas Cox @trcox.matrixandmetastasis.com is a Professor at the @garvaninstitute.bsky.social focussing on the Extracellular Matrix and Fibrosis in Cancer.
We interviewed Dr. Cox about his role as a founding member of the MRS Early Career Leadership Council 🧵👇

Save the date! OzMRS Symposium 2025 will take place at the University of Wollongong on the 29th and 30th of October. More information coming soon. #Metastasis #CancerResearch

New Review on Organ Repair & Fibrosis

Repeated organ injuries leads to abnormal ECM remodelling, disrupting tissue structure and function. Nice summary of the ECM's role in persistent fibrosis, organ-specific healing mechanisms, and anti-fibrotic strategies.

www.nature.com/articles/s44...

The extracellular matrix in cancer: from understanding to targeting Significant advances in matrix biology research have enhanced our understanding of individual matrix components and extracellular matrix (ECM) signall…

New review paper written by Jess Chitty in the team just out in Trends in Cancer (@cp-trendscancer.bsky.social) (OpenAccess)
The extracellular matrix in cancer: from understanding to targeting
| → www.sciencedirect.com/science/arti... ← |

June 4th = National Cheese Day 🧀 Sounds like a great excuse to eat one’s entire body weight in cheese 🤩 😋

Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...

Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells

www.nature.com/articles/s41...

My lab at the Center for Cancer Biology (UniSA, Adelaide, Australia) has a fully funded PhD position open to domestic or international students to explore the functions of alternative spliced isoforms in prostate cancer progression. @CCB_Research

www.unisa.edu.au/research/deg...

Join us in Lorne for the 13th International Proteoglycan Meeting & the annual scientific meeting of @mbsanz.bsky.social

Meet our Speakers! Over the next few weeks, we will feature each of the fantastic speakers who will join us in Lorne.

More information below - mbsanz2025.smalltalkevents.com.au

Join us in Lorne for the 13th International Proteoglycan Meeting & the annual scientific meeting of
@mbsanz.bsky.social!

Meet our Speakers! Over the next few weeks, we will feature each of the fantastic speakers who will join us in Lorne.

More information below - mbsanz2025.smalltalkevents.com.au

Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th...

A selective inhibitor of oncogenic JNK signalling perturbs metastatic outgrowth of triple-negative breast cancer through metabolic blockade

@sharissa-latham.bsky.social @davidrcroucher.bsky.social

connect.biorxiv.org/qr/qr_img.ph...

Don't miss the next ECLC webinar by Christine Desmedt, PhD on Opportunities of post-mortem tissue donation programs to advance metastatic cancer research - May 19th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - Register here us02web.zoom.us/webinar/regi...

DEADLINE APPROACHING for MRS Early Career Researcher travel scholarships.

Each award provides up to US$500 for attending national conferences, and up to US$750 for international conferences.

Closes 1st May 2025

Find out more metastasis-research.org/for-research...

Check out the next MRS webinar from @casanova-acebes.bsky.social

ECM remodeling is a fundamental driver of more than 50 chronic diseases, contributing to over 35% of deaths in the Western world. Join Dr. Morten Karsdal on a journey through 25 years of groundbreaking matrix biology.

Register for free here: ecm-congress.org/ecm-pharmaco...

The Matrix Biology Society of Australia & NZ (MBSANZ) is now on BlueSky bsky.app/profile/mbsa...
Follow for all things matrix biology related in Australia & NZ

🙄 @lornamilne.bsky.social

This looks cool. Will need to give it a try! 👍🏼

We have such an exciting program and speakers for our annual #EACR congress 🤩

Thanks to the many, many researchers who already submitted abstracts - and don't forget this week's March 6 abstract deadline ⏰ if you also want to join us in beautiful Lisbon!

2025.eacr.org

@helloeacr.bsky.social 🧪🔬⚕️

📣Join us at the 13th International Proteoglycan & #MBSANZ Scientific Meeting

🗓️ Dates: 27 - 31 October 2025
📍 Where: Mantra Lorne, Victoria, Australia

Don't miss out on this opportunity to engage with cutting-edge developments in #proteoglycan & #ECM research

👉 mbsanz2025.smalltalkevents.com.au

Vaccines can elicit long-lived immune activity against #pancreatic #cancer

Sethna et al, MSKCC, report that personalized vaccines encoding neoantigens can induce durable CD8+ T cell responses- correlating w/ better long-term outcomes 🧪⚕️

www.nature.com/articles/s41...
www.nature.com/articles/d41...