Matthew Ross

No kings.

The discovery reveals a new biomarker to aid in the early detection of disease and a potential target for more precisely tailored therapies — made possible by a collaboration between labs in different research divisions that defines the scientific culture Fred Hutch has nurtured for half a century.

We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country.

This Friday, where will you be?

standupforscience2025.org

Fred Hutchinson Cancer Center Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

The Termini Lab at Fred Hutch in Seattle is recruiting a Lab Aide to join our group - more information and instructions to apply can be found at the posting below 👇🧫👇🔬👇🐁
careers-fhcrc.icims.com/jobs/29265/l...

@science.org RNA polymerase II at histone genes predicts outcome in human cancer 🧬💊 @fredhutch.bsky.social @hhmi.bsky.social www.science.org/doi/10.1126/...

Two photos of Dr. Jon cooper: in the lab in the mid-1980s & during his final speech as division director in 2018.

Today we’re celebrating Dr. Jon Cooper’s retirement and his 40 years in Basic Sciences @fredhutch.bsky.social. We’re grateful for his many contributions to science and his service to Fred Hutch and the division, including serving nine years as division director. Congrats Jon!

This is an excellent paper with some truly exciting implications for improving cancer diagnosis and prognosis.

Cold air makes oxygen toxic for worms A new study from a postbaccalaureate researcher in Mark Roth’s lab at Fred Hutch Cancer Center, Cameron Suraci, shows that microscopic worms exposed to frigid temperatures (about 36 degrees Fahrenheit...

In a new study published in Frontiers in Physiology, the Roth Lab in @hutchbasicsci.bsky.social showed that microscopic worms can survive extreme cold & low oxygen by triggering a survival mechanism. This could offer insights into how humans might endure similar conditions. bit.ly/4gZu5Lo

Grant King, a postdoc in the lab of @harmitmalik.bsky.social, has been named a Hanna H. Gray Fellow by @hhmi.bsky.social — investing up to $1.5 million for up to eight years to help King achieve his goal of running his own lab. Read more: bit.ly/4hlRWFo

@hutchbasicsci.bsky.social

JOIN JOHN GREEN ON TOUR INDIANAPOLIS. IN March 15 BROOKLINE, MA March 16 NEW YORK, NY March 18 WASHINGTON, DC March 19 PHILADELPHIA, PA March 20 ATLANTA, GA March 21 IOWA CITY, IA March 22 ST. LOUIS, MO March 23 PLANO. TX March 24 HOUSTON. TX March 25 BOULDER, CO March 26 SAN MATEO, CA March 27 SEATTLE, WA March 28

Everything is TB Tour! Coming to you this March with some truly spectacular friends. Tickets will include a pre-signed copy of the book and are available now at everythingistb.com EXCEPT for Philadelphia, PA (available Friday). Excited to see you all!

At this point I’m seriously considering changing my name to Matthew Ross so I can see what all the fuss is about. 🧐

In this episode, I interviewed Dr. Harmit Malik (@harmitmalik.bsky.social), Professor and Associate Director of the Basic Sciences Division at the Fred Hutch Cancer Center (@fredhutch.bsky.social / @hutchbasicsci.bsky.social)

Stay up to date with every Matthew Ross on Bluesky by following the Matthew Ross Starter Pack! go.bsky.app/EwdnymS

We got it all! There is a Matthew Ross, another Matthew Ross, a Matt Ross, another Matthew Ross...

Four-component protein nanocages designed by programmed symmetry breaking - Nature Using viral capsid architectures as template for design, higher triangulation number nanocages that require symmetry breaking offer potential advances in targeted delivery and antigen-displaying vacci...

Could a tiny molecular soccer ball deliver vaccines and drugs to cells? The lab of UW's Dr. David Baker (2024 Nobel Prize Winner!), with Fred Hutch’s Barry Stoddard and Madison Kennedy, report the latest protein design results from their ongoing 25-year collaboration. www.nature.com/articles/s41...

Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations Rabies virus causes nearly 60,000 human deaths annually. Antibodies that target the rabies glycoprotein (G) are being developed as post-exposure prophylactics, but mutations in G can render such antib...

In new study, we measure how all mutations to rabies G affect cell entry & antibody neutralization

Sheds light on constraints on type III fusion proteins, suggests ways to stabilize G vaccine antigens, and quantifies antibody robustness to rabies variation

www.biorxiv.org/content/10.1...

We need more programs like this one to bring fresh perspectives into the biological sciences. As highlighted in the fellowship link, our lab is excited to co-advise fellows eager to tackle the world’s biggest challenges using cutting-edge tools. Feel free to DM me if you’d like to talk!

2024 Annual Report The 2024 Annual Report from the Basic Sciences Division at Fred Hutch features the divisions reflections for the year, as well as celebrations of faculty retiring and joining the division, events and...

2024 was an amazing year for Basic Sciences @fredhutch.bsky.social, including the opening of the @yarimura.bsky.social Lab, the Pathfinders Postdoc Symposium, a wonderful retreat, many scientific discoveries, and more. Get all the highlights in our annual report: www.fredhutch.org/en/research/...

Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance H5 influenza is considered a potential pandemic threat. Using deep mutational scanning, this work reveals how the >10,000 different possible amino-acid mutations in hemagglutinin affect cell entry, re...

The final version of our study using pseudovirus deep mutational scanning to measure the effects of mutations influenza H5 hemagglutinin to inform viral surveillance is now published in PLoS Biology:
journals.plos.org/plosbiology/...