Tatiana Prowell, MD

#MedSky #IDSky #OncSky
NEW RPCT: 5, 10, or 15d of Paxlovid in 156 immunocompromised (IC) outpatients w/ #COVID19. No diff in sustained viral suppression d15-44.
🔑 takeaways: Rebound isn’t rare (1 in 4 of severely IC), & enrichment/endpoint selection matter.

www.sciencedirect.com/science/arti...

📣 NEW #MedSky: #SARSCoV2 spike persists in skull/meninges/brain in people with #COVID19 infection.
In mice, spike is sufficient to induce brain #PathSky & #PsychSky behavioral changes & exacerbates #NeuroSky damage.
mRNA vax reduced but didn’t eliminate spike burden. /1
#LongCovid

Are you a top US-based scientist wanting to relocate to Australia? We are now calling for formal applications from both Australian and non-Australian citizens based in the US whose work is internationally recognised as exceptional.
📅 Applications close: Aug 29, 2025
🔗 science.org.au/gtap/?utm_so...

#MedSky #OncSky #IDSky
Prosp cohorts (China, N=74K):
At 8-10 yrs, EBV VCA-IgA was assoc w/:
Overall cancer risk ⬆️ 5x
Lung cancer 1.8x
Liver cancer 1.7x
Nasopharyngeal cancer 26x Lymphoma 3.2x
Dose-response +.

🔑 We need ways to prevent/treat mono.

#DrugDevelopment
www.nature.com/articles/s41...

#MedSky #IDSky
📢 Prospective cohort study (CO-FLOW) of adults hospitalized for #COVID19 finds only 1 in 8 fully recovered at 3m, & only 1 in 4 at 3y. More than half had ⬇️ memory & concentration at 3y. This is #LongCovid. HUGE unmet #DrugDevelopment need.

www.thelancet.com/action/showP...

#MedSky #LongCovid
NEW study of outpatients w/ #COVID19 + self-reported #BrainFog after infection vs healthy controls finds marked hypometabolism on PET & brain wave changes on EEG corresponding to areas responsible for attention, memory, language, & decision-making. www.nature.com/articles/s41...

Top F.D.A. Official Overrode Scientists on Covid Shots

#MedSky #IDSky #COVID19 #PublicHealth

www.nytimes.com/2025/07/02/h...

📣 Calling future oncologists with at least 1y of #oncology training! Apply by 7/9/25 to attend the FDA- @ascocancer.bsky.social Fellows’ Day Workshop: secure-web.cisco.com/1VqNN4qO1FuT...

👉 9/25/25: in person (ASCO HQ, in DC area)
or
👉 1/29/26: virtual

See you there! #MedSky #OncSky #MedEd

NIH-funded science must now be free to read instantly: what you should know US biomedical agency’s public-access policy kicks in on 1 July. Nature talks to specialists about how to comply.

Starting July 1, researchers funded by the US National Institutes of Health will be required to make their scientific papers available to read for free as soon as they are published in a peer-reviewed journal. Nature asks experts what researchers need to know about the NIH policy. #Academicsky 🧪

An image of the brain generated by ChatGPT which has mislabeled almost every brain structure and even invented new ones,

Screenshot of LLM offering to generate the image "Would you like a visual diagram of how the cerebellum interfaces with cortical prediction pathways in this framework?"

ChatGPT offered to make an image for me of how the cerebellum interacts with other brain predictive processing pathways and this amazingly confused diagram was the result--mislabeling almost every brain structure & even inventing new ones. 😱 Let's hope our future doctors aren't using LLMs to study!

Thank you! Very helpful!!

a man looking through a magnifying glass at his face ALT: a man looking through a magnifying glass at his face

Has anyone in #MedSky or #PathSky used a clip on microscope for iPhone? How did it work? Any tips/tricks for choosing one or using one? Thanks!

Structured Exercise after Adjuvant Chemotherapy for Colon Cancer | NEJM Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking. In this phase 3, randomized trial conducted at 55 centers, ...

#ASCO25 #OncSky #crcsm

NEW: Randomized trial of exercise vs health ed in people w/ #ColonCancer after adjuvant chemo: disease-free (HR 0.72; 6.4% abs diff at 5y) & overall (HR 0.63; 7.1% abs diff at 8y) survival improved w/ exercise! NNT ~14. ACTUALLY tolerable. 🏆

www.nejm.org/doi/full/10....

What podcasts do you follow for #ASCO25 content?

The @ascocancer.bsky.social Ed Book is the highest-quality, peer-reviewed, FREE #oncology #MedEd ever. Whether or not you’re at #ASCO25, don’t miss this resource, #OncSky #MedSky, #MedStudentSky! Drop a 📌 in the comments to bookmark the link for later.

ascopubs.org/toc/edbk/cur...

#OncoAlert

Financial Toxicity interventions can address many key financial friction points: Universal Financial Toxicity Screening (COST vs abbreviated COST) Routine Use of Financial Navigators/Up Front Financial Counselling Improve Provider Education about Financial Concerns and Resources Regular Cost Conversations Tailored Patient Interventions Based on Specific Needs …but Parking Should be FREE for ALL Patients

🚨 Excited to be speaking in the FIRST #bcsm session at #ASCO25:
"Addressing #FinancialToxicity in #BreastCancer Care: Strategies for Mitigation and Support"

👉Education Session
🎯 Hall D2
📆 TODAY, May 30, 2025
⏲️ 1:00 - 2:15 PM CDT

My 🗝️ @ascocancer.bsky.social takeaways are below ⬇️
Don't miss it!

America’s brain drain

No words

🙏

I’ve never read it either. Maybe I should try to do it real time with you!

Experts Say CDC Cuts Will Cost Lives This Medical News article discusses how recent workforce and program reductions at the US Centers for Disease Control and Prevention will affect public health.

Experts inside and outside the US Centers for Disease Control and Prevention (CDC) have been left stunned and puzzled by the decimation of a nearly 80-year-old agency that has been a global leader in public health.

Learn how decimating the CDC will cost many lives in the US and abroad. #MedSky

Awww what a nice thing to say, @jabarocas.bsky.social. Makes me feel old in a nice way. 😊

Ok #OncSky, what social media platforms do you plan to use most for #ASCO25 content? (And yes I know I’m asking on BlueSky so…). Can’t do a poll here but please vote in replies! #MedSky

Twitter
BlueSky
LinkedIn
Instagram or other

The most important thing everyone in medicine & science can do right now is #mentorship. Having even one physician/scientist to serve as a sounding board & role model matters so much. #MedSky

From the research and writing SUPER AGERS, some of the practical steps I've incorporated (and suggest avoiding) for extending healthspan
gift link www.wsj.com/health/welln...

My daughter’s speech therapist went out of business because Medicaid reimbursement rates were too low. We do not have Medicaid. I’m going to keep posting this until people understand that when Medicaid gets cut *everyone* loses services.

The Microbiome and Cancer: A Review This review in the Translational Science series summarizes current evidence regarding the human microbiome and cancer, including how the microbiota in the gut and other anatomical locations affect can...

#MedSky #OncSky #IDSky #DrugDevelopment #MedEd

If you want to get up to speed on the #microbiome in #cancer literature, this review is an excellent summary.

jamanetwork.com/journals/jam...

That’s an outstanding question. I don’t know that it’s ever been asked. #MedSky

❤️‍🩹❤️‍🩹❤️‍🩹

We need ACP, ABIM, NBPAS, & others to educate #MedSky on #LongCovid & #MECFS. These aren’t new conditions. They cause marked disability & impair quality of life. We really need #MedEd now. Many clinicians are still telling these pts they “just need to exercise.” /End

#MedSky #LongCovid
For more info: www.atsjournals.org/doi/abs/10.1...

Thinking about all the patients w/ acute #COVID19 illness who were hypoxemic but not breathless & whose O2 improved w/ proning. All of this was a clue that such shunt physiology may be important in this illness (& sequelae). /2