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The Wells Lab of UCLA

@wellslab.bsky.social

We use human stem cells to study neurodevelopmental and psychiatric disorders in the Department of Human Genetics at UCLA. https://wellslab.dgsom.ucla.edu/

88 Followers  |  59 Following  |  4 Posts  |  Joined: 13.09.2023  |  2.3005

Latest posts by wellslab.bsky.social on Bluesky

We have many other projects in the works that will make use of this system, including studies of human brain cell responses to a range of genetic perturbations and environmental exposures--stay tuned!

30.09.2025 19:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

We detected rare and common genetic variants associated with between-donor differences in neural progenitor cell proliferation, as well as a genetic modifier of lead (Pb) sensitivity (the between-donor differences in Pb sensitivity was MASSIVE btw, much to our surprise).

30.09.2025 19:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

This new platform combines our cell village approach--in which cells from multiple different donors are pooled into a shared in vitro environment--with a novel computational model called "Townlet" that is specifically tailored for village datasets.

30.09.2025 19:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The first (of hopefully many) reports to come from our collaboration with @hjp.bsky.social

We present a new type of cell fitness assay that allows you to both quantify and explain differences across human donors in cell proliferation and sensitivity to environmental toxicants.

30.09.2025 19:17 β€” πŸ‘ 17    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
Human Genetics | Genomic Scientist Fellows | UCLA Medical School The Emerging Genomic Scientist Fellows Program is a cornerstone of justice, equity, diversity, and inclusion initiatives in the Department of Human Genetics.

Are you a senior grad student or new post-doc in genetics/genomics who has demonstrated a strong commitment to DEI?

Apply by Feb 7th for the 2025 Emerging Genomic Scientist Symposium hosted by the UCLA Human Genetics JEDI committee.

For more info: medschool.ucla.edu/departments/...

13.11.2024 22:26 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

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