Jana U'Ren

Zoomed-in photograph of fungus growing on solid media

I'm super excited that our photo of Xylaria was selected for the cover of the August issue of #mSystems! journals.asm.org/toc/msystems...

This complements our recent article on the secondary metabolism of xylarialean fungi (Franco et al., 2025 vol. 10, e00468-25). @ernestofranco.bsky.social

20.08.2025 05:15 — 👍 1    🔁 1    💬 0    📌 0

Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi | mSystems Saprotrophic and endophytic xylarialean fungi are among the most prolific producers of bioactive secondary metabolites, with numerous industrial uses as antibiotics, pharmaceuticals, and insecticidal ...

Excited to have our paper out in #mSystems. Pairwise co-cultures of only 7 xylarialean strains yielded >6k unique metabolites vs. 2k from monocultures. High richness reflects an abundance of interaction-specific metabolites. Work led by @ernestofranco.bsky.social
journals.asm.org/doi/10.1128/...

09.06.2025 21:20 — 👍 1    🔁 1    💬 0    📌 0

Postdoctoral Research Fellow If you have any questions about the position or our application process, reach out to us at recruiting-u@smith.edu. Job Description Postdoctoral Positions: Bioinformatic and single-cell ‘omics approac...

Postdoc opp at Smith College w/ Laura Katz (start 01-Apr-2025) smithcollege.wd5.myworkdayjobs.com/en-US/smithc...
Genome evolution in microeukaryotes focusing on bioinformatic analyses diverse amoebae, incl species sampled from extreme envs. ?s: lkatz@smith.edu. Appl review begins 15-Feb-2025

03.02.2025 16:52 — 👍 5    🔁 3    💬 0    📌 0

Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome-specificity Carbonic anhydrase (CA) enzymes catalyze the interconversion of carbon dioxide and bicarbonate with an efficiency exceeded only by superoxide dismutase. CA enzymes have convergently evolved multiple t...

Our new preprint is out! A genomic and metagenomic dive into the diversity of microbial carbonic anhydrases. Huge thanks to the amazing team who made this possible!
@you-wren.bsky.social @laurameredith.bsky.social
www.biorxiv.org/content/10.1...

14.01.2025 12:47 — 👍 2    🔁 2    💬 0    📌 0

Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi Xylariales is one of the largest and most ecologically diverse fungal orders. Xylarialean fungi are well-known for their chemical diversity, reflecting a hyperdiversity of biosynthetic gene clusters (...

Excited to share our latest preprint! 'Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi'. Deeply grateful to the U'Ren Lab @you-wren.bsky.social and JGI team.
tinyurl.com/u32xdpx9

07.01.2025 06:20 — 👍 2    🔁 1    💬 1    📌 0