Michael Platten, MD's Avatar

Michael Platten, MD

@michael-platten.bsky.social

Neurologist, Chair of Neurology Brain Tumor Immunotherapy @dkfz.bsky.social @platten-lab.bsky.social @uniheidelberg.bsky.social Medical Faculty Mannheim Founder Tcelltech President @eanoassociation.bsky.social Ambassador for the @erc.europa.eu

1,458 Followers  |  182 Following  |  23 Posts  |  Joined: 15.11.2024  |  2.1884

Latest posts by michael-platten.bsky.social on Bluesky

an incredibly dedicated team of clinical trialists, basic and translational researchers and immune monitoring team @dkfz.bsky.social, @dkfz-iic.bsky.social, I have the privilege to work with with the goal to develop a viable tratment for patients with this devastating disease. 5/5

29.07.2025 12:34 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@neurooncologyhd.bsky.social @neurooncotue.bsky.social, Frankfurt, Mannheim, all patients and their relatives, Roche for the in-kind contribution of atezolizumab, the fantastic research collaborators @bihatcharite.bsky.social and HI-TRON, and first and foremost 4/

29.07.2025 12:34 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

in this "reverse translation" trial which was supported by the German Cancer Aid. Huge thanks to @dkfz.bsky.social as the trial sponsor, the fantastic NCT Trial Center, all participating sites from the Neurooncology Working Group @krebsgesellschaft.bsky.social 3/

29.07.2025 12:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A H3K27M-targeted vaccine in adults with diffuse midline glioma - Nature Medicine In this compassionate use study, treatment of adult patients with H3K27M-mutant diffuse midline glioma with a long peptide vaccine targeting H3K27M led to vaccine-induced peripheral T cell immune resp...

combined with radiotherapy and the immune checkpoint inhibitor atezolizumab. The trial was based on encouraging results in patients with recurrent diffuse midline gliomas

www.nature.com/articles/s41...

We will now follow-up our patiens, analyze the data and continue our analyses 2/

29.07.2025 12:34 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Excited to announce that we have completed accrual of the INTERCEPT-H3 trial (NCT04808245). This phase 1 first-in-human trial explores safety and immunogenicity of a long peptide vaccine targeting the clonal driver mutation H3K27M in adult patients with newly diagnosed diffuse midline gliomas 1/

29.07.2025 12:34 β€” πŸ‘ 13    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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πŸ“£ Have you heard? Registration for #EANO2025, taking place Oct 16-19, 2025 in #Prague (CZ) is open! Don’t miss out on this fantastic experience to meet experts in the field of #NeuroOncology. Early Bird fees available until July 31, 2025. πŸ‘‰ eano.eu/eano2025/reg... #braincancer #medsky

18.06.2025 12:50 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1
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🧠 June 8 is #WorldBrainTumorDay β€” raising awareness & understanding of brain tumors.
EANO supports progress in #NeuroOncology through research, education & collaboration.
πŸ”— Learn more: www.eano.eu
#btsm #BrainTumor #Oncology

08.06.2025 09:44 β€” πŸ‘ 11    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Der Wissenschaftsrats-Vorsitzende Wolfgang Wick mit dem nebenstehenden Zitat "Wir brauchen eigenstΓ€ndige Wissenschaftsinfrastrukturen in Europa", das aus einem FAZ-Gastbeitrag vom 4.6.25 stammt.

Der Wissenschaftsrats-Vorsitzende Wolfgang Wick mit dem nebenstehenden Zitat "Wir brauchen eigenstΓ€ndige Wissenschaftsinfrastrukturen in Europa", das aus einem FAZ-Gastbeitrag vom 4.6.25 stammt.

Wissenschaft braucht verlΓ€ssliche Infrastrukturen - viele davon liegen noch in den USA. Der WR-Vorsitzende
@wickwolfgang.bsky.social fordert in der @faznet.bsky.social eine europΓ€ische Strategie fΓΌr mehr UnabhΓ€ngigkeitπŸ‘‰ www.faz.net/aktuell/wiss...
#DigitaleSouverΓ€nitΓ€t #Forschung #Infrastruktur

04.06.2025 10:27 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Join us this week on Thursday (22nd May) for our next i2 seminar! This week it’s all about T cells in cancer!

19.05.2025 06:23 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The organizing committee of the UNITE conference would like to thank all speakers for their excellent presentations and all participants for the valuable discussions. @wickwolfgang.bsky.social @michael-platten.bsky.social

15.05.2025 14:08 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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🧠 Join the next #EANOYoungsters Journal Club on June 5, 16:30–17:30 CEST!
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
πŸ“Free & open to all EANO members
πŸ”— www.eano.eu
#NeuroOncology #BrainTumors #JournalClub

15.05.2025 09:45 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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The second day of the UNITE conference. Today there will also be a contribution from a patient on the book β€œAlles gut? Alles gut.” by Marlene Assmann. www.jacobystuart.de/buecher-von-...

15.05.2025 08:36 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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Bottom-up synthetic immunology - Nature Nanotechnology This Perspective highlights bottom-up molecular engineering and modular nanobiotechnological approaches for developing effective immunotherapeutics and their potential in personalized medicine.

The SynthImmune project by Heidelberg University& partner institutes advances a "bottom-up" synthetic biology approach to immunotherapies.
Hoping they do well in the German government's Excellence Strategyβ€”anticipating the announcement on 22 May.

Perspective article: www.nature.com/articles/s41...

14.05.2025 07:38 β€” πŸ‘ 14    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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⏱️ Clock is ticking! Final call for abstract submissions for #EANO2025 in #Prague. Don't miss this chance to share your work contribute to the advancement of #NeuroOncology. Submit now via our official event website: www.eano.eu/eano2025/ until May 6, 2025, 23.59 CEST!
@oncoalert.bsky.social

06.05.2025 11:58 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy - Nature Biotechnology Tumor-reactive T cell receptors are rapidly identified from lymphocyte scRNA-seq data.

Fantastic initiative - we could offer to provide our predicTCR and makeTCR tools to identify tumor-reactive TCRs and clone them for testing.

www.nature.com/articles/s41...

www.biorxiv.org/content/10.1...

02.05.2025 10:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
UNITE CONFERENCE - UNITE Glioblastoma Conference

Wir freuen uns, die UNITE-Glioblastom-Konferenz ankΓΌndigen zu kΓΆnnen, die am 14. und 15. Mai 2025 im DKFZ-Kommunikationszentrum in Heidelberg stattfinden wird. melden Sie sich heute an: www.unite-glioblastoma.de/unite-confer...

02.05.2025 09:08 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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πŸš€ We are proud to launch the new "Ambassadors for the ERC" initiative, together with @ercgrantees.bsky.social !

We aim to empower researchers across Europe to advocate for frontier research. Find out more πŸ‘‰ bit.ly/44bQzp7

🌟 Excited to see what can be achieved!

#Amb4ERC

29.04.2025 07:01 β€” πŸ‘ 52    πŸ” 18    πŸ’¬ 1    πŸ“Œ 9
Photo: Jung/DKFZ

Photo: Jung/DKFZ

@michael-platten.bsky.social has been selected and nominated as Ambassador for the ERC network. The @erc.europa.eu & the @ercgrantees.bsky.social launched the new Ambassadors on 28 April. This joint initiative aims to promote investment in frontier research and highlight the importance of #research.

30.04.2025 10:53 β€” πŸ‘ 32    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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πŸ—“οΈ Only one week to go! The abstract submission deadline for #EANO2025 in #Prague is approaching fast. This is your opportunity to share your findings, collaborate with peers, and be recognized in the field of #NeuroOncology. Submit your abstract now: www.eano.eu/eano2025/ #btsm

23.04.2025 21:16 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Apply to DKFZ Marie SkΕ‚odowska Curie MasterClasses

Apply to DKFZ Marie SkΕ‚odowska Curie MasterClasses

Do you want to do your #postdoc in #cancerresearch with the most prestigious #fellowship in Europe? Apply to DKFZ Marie SkΕ‚odowska Curie MasterClasses by May 19. Projects in #cellandmolecularbiology #genomics #bioinformatics #immunology #medicaltechnology, #epidemiology.
Apply here: t1p.de/nx6tu

22.04.2025 13:50 β€” πŸ‘ 11    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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#brain #tumors | Michael Platten This is the research team DKFZ Deutsches Krebsforschungszentrum Helmholtz-Gemeinschaft UniversitΓ€t Heidelberg UniversitΓ€tsmedizin Mannheim Neurooncology Heidelberg Health + Life Science Alliance I hav...

www.linkedin.com/posts/michae...

19.04.2025 20:49 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen - Nature Communications Vaccination in glioblastomas does lead to the emergence of tumour-antigen-specific T cells but T cell dysfunction, poor tumour infiltration and persistence hinder efficient tumour killing. Here author...

πŸš€ New publication! We developed a PTPRZ1-specific TCR-T cell therapy for glioblastoma.

πŸ”¬ Key findings:
βœ… Identified a PTPRZ1-reactive TCR from a vaccinated patient
βœ… Kills glioblastoma cells with no off-target effects
βœ… Eliminates tumors in murine brain models

πŸ”— www.nature.com/articles/s41...

11.02.2025 11:29 β€” πŸ‘ 34    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0

Don’t miss our i2 seminar today at 4 pm where we will hear more about immunogenic cancer editopes and the lineage tree of tissue macrophage development.
Join us for a lively discussion and snacks and drinks! πŸ§ͺ
Today at 4pm in the main building πŸ‘‡

17.04.2025 08:27 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Don't forget to register - only one week left!

17.04.2025 09:07 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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πŸš€ Just 2 weeks left to submit your abstract for #EANO2025 in #Prague! Don't miss your chance to share your research with the world. Submit your work by April 30 and join us for an incredible event this October. We can't wait to see your contributions! πŸ”¬ eano.eu/eano2025/

16.04.2025 11:01 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Huge congrats @lukasbunse.bsky.social, so well deserved, fantastic achievement.
@hlsalliance.bsky.social @cn-hd.bsky.social @neurooncologyhd.bsky.social @mctneuroscience.bsky.social @platten-lab.bsky.social

28.03.2025 11:54 β€” πŸ‘ 19    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0
EANO Meeting 2024 in Glasgow
YouTube video by EANO EANO Meeting 2024 in Glasgow

🌍 #EANO2024 in Glasgow gathered 1,200+ global participants, featuring cutting-edge research and insights to shape the future of #NeuroOncology. Be part of this community at #EANO2025! Watch our highlight video & renew your membership today for many benefits! bit.ly/4i6djdF
See you in Prague! πŸ‘‹

27.03.2025 09:48 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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πŸš€From Glasgow to Prague: Shaping the Future Together! #EANO2024 in Glasgow was a huge success with unforgettable moments & inspiring talks! Watch the highlights bit.ly/3WL1oKg and get excited for #EANO2025 in Prague! What are you most excited about? #NeuroOncology

19.03.2025 10:35 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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πŸ“… Mark your calendars! Abstract submissions for #EANO2025 are due April 30. Don’t miss your chance to showcase your #NeuroOncology research this October! 🌍✨
πŸ”¬ Submit now: www.eano.eu/eano2025/abs... #btsm #neurosurgery #glioma #RadOnc #BrainCancer #cancernurse #AHP

11.03.2025 08:36 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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πŸ“£ Still time to register! Join the 3rd Annual Highlights of EANO/SNO 2024 webinar and hear key insights from #EANO2024 (Glasgow) and #SNO2024 (Boston).

πŸ—“ March 7, 2025 | ⏰ 6:30 PM CET | 12:30 PM ET
πŸ”— Register now: eano.eu/eanowebinar/

@neuroonc.bsky.social

06.03.2025 08:40 β€” πŸ‘ 11    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1

@michael-platten is following 20 prominent accounts