Andreas Linkermann's Avatar

Andreas Linkermann

@linkermannlab.bsky.social

Chair 5th Med Dept UMM, Heidelberg University Kidney Transplantation and Cell Death Biology

114 Followers  |  146 Following  |  10 Posts  |  Joined: 19.08.2025  |  1.4108

Latest posts by linkermannlab.bsky.social on Bluesky

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David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.

Obituary: David Baltimore (1938-2025) virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS

go.nature.com/443Vojo

01.12.2025 12:33 β€” πŸ‘ 62    πŸ” 17    πŸ’¬ 0    πŸ“Œ 3

Guess we DO, @ms-balzer.bsky.social

07.11.2025 20:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E - Gavali - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...

04.11.2025 11:57 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Host cell Z-RNAs activate ZBP1 during virus infections - Nature Nature - Host cell Z-RNAs activate ZBP1 during virus infections

Congrats to the wonderful Sid Balachandran and team!

www.nature.com/articles/s41...

15.10.2025 12:30 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Registration is open: register for the first #MMPUResearchDay taking place in #Mannheim at #CubexOne on Oct 13, 2025. A great line-up of scientists from #MMPU, #EMBL, #UMM, #UKHD.

11.09.2025 10:02 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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Hydroxyestradiol alleviates acute kidney injury via blockade of ferroptosis The molecular mechanisms underlying sex differences in acute kidney injury (AKI) remain incompletely understood. In a study recently published in Natu…

Very pleased to share this "spotlight" in Trends in Endocrinology and Metabolism which refers to our recent work.

www.sciencedirect.com/science/arti...

17.09.2025 19:33 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I do, indeed!

17.09.2025 10:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury - Cell Death & Differentiation Cell Death & Differentiation - Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury

Here is a "highlight" on our recent work written by Boyi Gan for Cell Death and Differentiation:
www.nature.com/articles/s41...

31.08.2025 06:19 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Warum Frauen seltener ein akutes Nierenversagen erleiden – Deutsches Γ„rzteblatt

www.aerzteblatt.de/news/warum-f...

28.08.2025 15:37 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Estrogen-powered kidney protection Estrogen protects against kidney injury through both genomic and nongenomic mechanisms.

This refers to our recent manuscript.
Estrogen-powered kidney protection | Science Signaling www.science.org/doi/10.1126/...

27.08.2025 11:42 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD - Nature Nature - STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD

STING drives #necroptosis, and here’s how it does it!
Congratulations to @gianmaria-liccardi.bsky.social and his amazing team!

www.nature.com/articles/s41...

20.08.2025 23:31 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature 17Ξ²-oestradiol establishes an anti-ferroptotic state in female kidney tubules.

Happy to start at Bluesky with a post on our recent manuscript at @nature.com:

www.nature.com/articles/s41...

Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.

19.08.2025 08:57 β€” πŸ‘ 35    πŸ” 15    πŸ’¬ 4    πŸ“Œ 2

Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV

18.08.2025 15:42 β€” πŸ‘ 33    πŸ” 12    πŸ’¬ 2    πŸ“Œ 0

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