Daniel Medina-Cano

Hello everybody,
I am looking for an Engineer (IE) to help me start the lab at LBMC / ENS-Lyon in April.
We will investigate chromatin organization during replication in yeast.
RT appreciated!
To apply: inserm.softy.pro/offre/187863

@lbmcinlyon.bsky.social
#NewPI #3DGenome #chromatin #replication

Evaluating the effects of archaic protein-altering variants in living human adults Promise and pitfalls of using large biobanks to study impacts of archaic protein-coding variants in living humans.

While stories of singular DNA changes that drove evolution of human brain/behaviour remain seductive, advances across multiple fields of biology cast doubt on such simplistic narratives of our origins. A new paper from my lab shows how biobanks may speak to this fundamental question.🧪
Explainer🧵👇1/n

Research - Human Technopole Human Technopole’s research is based on a mix of fundamental and translational research. We will host extensive core expertise in basic research in areas relevant for the understanding of human biolog...

🎉 In January, I will join the new "Multimodal AI Across Scales" research area at the @humantechnopole.bsky.social in Milan 🎉

More soon, but for now: my lab and the new area will have postdoc, RSE, and PhD positions available.

Feel free to reach out if interested!

humantechnopole.it/en/research/

Modelling co-development between the somites and neural tube in human trunk-like structures - Nature Cell Biology Makwana, Tilley et al. generate human stem cell-based trunk-like structures approximating Carnegie stage 13–14 of development. They use them to model and study the development of the thoracic and lumbar trunk.

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!

www.cam.ac.uk/jobs/univers...

Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation Inge et al. show that human endoderm originates from two converging developmental routes with distinct dynamics and efficiencies yet similar developmental potential. Combinatorial activin and BMP4 sig...

So exciting to see this in print! Ever wondered how embryonic cells know what (fate) to become during early development? In particular when they might see different signaling cues? We investigated this!

And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social!

www.cell.com/developmenta...

🚨 We are hiring a group leader in Virology at CIRI !

Join us in the beautiful city of Lyon 🇫🇷

Deadline on March 31st 2026

We moved the AI@MBL course "Deep Learning for Microscopy Image Analysis" to HHMI Janelia (@hhmijanelia.bsky.social).

Join us for two weeks of intense lectures, exercise, and hands-on project work!

Course dates: June 4-18 2026
Application by: January 15 2026

www.janelia.org/you-janelia/...

Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)

Conservation and alteration of mammalian striatal interneurons - Nature An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...

1/ Happy to share important work done with my co-author Andrew Khalil in the labs of Rudolf Jaenisch @whiteheadinstitute.bsky.social @mit.edu and David Mooney @harvard.edu @wyssinstitute.bsky.social trying to assess and fix the major problem of transgene silencing in human ESC/iPSC based work

Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social

Just a friendly reminder that we’re hiring for the Department of Neuroscience at The Ohio State University!! 🧠 The start of application review has been moved to this Friday, 10/17, but we’ll continue accepting applications until the position is filled!

neurojobs.sfn.org/job/39081/te...

Early career group leaders We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...

Lab’s 1st preprint!

Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.

@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.

He is on the job market!

Ready to start your own independent research programme?

We're inviting applications for early career group leaders in all areas of biology and biomedicine @crick.ac.uk

Apply by 27 Nov 2025:
www.crick.ac.uk/careers-stud...

#EarlyCareerResearchers #GroupLeader #ScienceCareers

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

The Crick is looking for new junior group leaders! Any postdocs or early career researchers wanting to be our colleagues should apply 👍

SciLifeLab launches major recruitment call for staff scientists in computational biology, data science and AI Computational methods and artificial intelligence on large-scale molecular data are transforming the study of biological systems and processes, ranging from molecular structures and cellular processes...

We’re launching a major #recruitment call for staff scientists in #ComputationalBiology, #DataScience, and #AI to strengthen Sweden’s life science research. 🧪🖥️

Positions are based at SciLifeLab sites across Sweden’s leading universities.

Learn more and apply ↓
www.scilifelab.se/news/scilife...

We are recruiting!

Visit www.cruk.manchester.ac.uk/careers/ for full details of all current vacancies, including:

🥼New Group Leaders [Apply by 2nd November]

🧪Postdoctoral Researchers with @sylvaindelaunay.bsky.social & @clausjorgensen.bsky.social

⚛️ #MassSpectrometry Technologist

More below 👇

Human brain organoids record the passage of time over multiple years in culture https://www.biorxiv.org/content/10.1101/2025.10.01.679721v1

Looking forward to working with new colleagues on a collaborative project in lung disease modelling and transcriptomics - please share! And email Jenny @jennydickens41.bsky.social, or me, with any questions. 😀

www.jobs.cam.ac.uk/job/52936/

🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇

Ventricle position can be remodeled after heart looping!
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️

Our call for PhD students within our International Max Planck Research School for Cell, Developmental and Systems Biology is open! Apply until October 28th. We are looking forward hearing from you! imprs.mpi-cbg.de

Careers at LIBD | Medical Research Jobs | Lieber Institute View our career opportunities with Lieber Institute for Brain Development including investigators, medical research jobs, scientists, & lab techs

We have several positions open at various levels (Research Assistant, Research Associate, Postdoctoral Fellow) across our highly interactive teams in the Division of Translational Neuroscience 🧠🔬🧪 @lieberinstitute.bsky.social

www.libd.org/careers/

Links to individual positions in the thread below.

Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...

Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...

CRISPR activation for SCN2A-related neurodevelopmental disorders Nature - Using SCN2A haploinsufficiency as a proof-of-concept, upregulation of the existing functional gene copy through CRISPR activation was able to rescue neurological-associated phenotypes in...

SCN2A loss is strongly linked to neurodevelopmental delays and, at times, seizure. In an amazing collaboration with @nadavahituv.bsky.social, led by Serena Tamura, Andrew Nelson, and Perry Spratt, we leveraged CRISPR activator approaches to rescue this loss.

rdcu.be/eGU0W

🚨 2 Postdoc openings in Neuroscience – Liège, Belgium 🚨

We are recruiting for a project on brain development & autism that includes:

⚡ Neuropixels recordings
⚡ Opto/chemo
⚡ Behavior
⚡ Neural network modeling

If you know someone, tag them or RT for visibility! 🙏
www.fens.org/careers/job-...