Ankur Sharma

This is game changer!!

Spatial multi-omics reveals cell-type-specific nuclear compartments

Two-layer DNA seqFISH+
Simultaneous mapping of 100,049 genomic loci
+ nascent transcriptome for 17,856 genes in single cells

www.nature.com/articles/s41...

Run a lab at an international cancer research centre in Melbourne, Australia!
Applications open until May 9th….
👇👇👇

Bsky vs Twitter engagement difference now 50-fold...

Very excited to launch CELLOGRAMRx a joint project between Australia 🇦🇺 (NHMRC) & Japan 🇯🇵 (AMED) teams to build a pan cancer atlas of oncofetal cells, understand population level differences and identify novel therapeutic targets by employing spatial omics & machine learning approaches!

EPFL Life Sciences Early Independent Research Scholar (ELISIR) From exceptional PhD directly to independent group leader

Fantastic opportunity: 🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH
👉 go.epfl.ch/ELISIR

It was great to visit IIT-Kanpur and Delhi University his week and interact with colleagues Amit Dutt, Hamim Zafar, Arun Shukla, Ananda, Santosh and others.. discussing common grounds between developmental biology and cancer.. also an opportunity to revisit old memories of undergrad days..

We are here 🦋. Save the date for Oz Single Cell 2025, 23-25 May in Sydney

I’ll be speaking at DU south campus and talking about our recent work. Thank you Amit Dutt for kind invitation. This is an special for me as 20 years ago I did my first internship as undergraduate at DU Genetics dept which ignited my interest in genome biology 🧬

Scientists can be classified as either Foxes or Hedgehogs; borrowing Isaiah Berlin’s famous use of the saying that “a fox knows many things, but a hedgehog knows one big thing”

Hedgehogs: Darwin, Monod, McClintock, Dawkins, Kimura..

Foxes: Wallace, Jacob, Brenner, Gould, Ohta..

Nutrient-driven histone code determines exhausted CD8+ T cell fates ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR T cells) also resisted acquiring TEX-like properties, exhibiting reduced CD39 expression when co-cultu...

The fate of T cells, such as seen in exhausted T cells, is tied to nutrients. This introduces the potential of therapies directed at keeping T cell identity and function intact. (And the infamous Krebs cycle makes a comeback to my brain)

www.science.org/doi/10.1126/...

Find out more about Prof Cindy Ma @garvaninstitute.bsky.social & her journey @jexpmed.bsky.social. Cindy is in the Precision Immunology Program & will be our new Faculty Chair in 2025!

rupress.org/jem/article/...

Method of the Year 2024: spatial proteomics - Nature Methods Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.

I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...

Done :)

WEHI - The Sir Gustav Nossal Professor of Immunology - Alumni Global The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...

📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.

The Immune Response

Source: Big Picture & Wellcome Trust
HD: www.tes.com/teaching-res...

Done :)

If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs

Great work Seth, can you add me?

YouTube video by Garvan Institute of Medical Research Welcome to Garvan

At Garvan, we see a future where everyone lives a longer, healthier life.

We bring together world-leading researchers and clinicians, collaborating locally and globally, to improve human health.

www.youtube.com/watch?v=FOIP...

#science #medicalresearch #health #disease

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Done :)

go.bsky.app/QW8Ghu5

Done :)

‘A place of joy’: why scientists are joining the rush to Bluesky Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.

‘A place of joy’: why scientists are joining the rush to Bluesky

For me, it certainly feels good to be here!

@natureportfolio.bsky.social @bsky.app

www.nature.com/articles/d41...

Five months into new gig! Here we are building world class team in Oncofetal research at Garvan Institute! We are looking for a computational biologist with proven track record in spatial biology, if you are keen to explore neighbourhoods drop a text :)

@jleslie1.bsky.social welcome mate!

Done :)

Done :)

We have a new position for a bioinformatician / computational biologist exploring genomic and epigenomic features of #cfDNA to uncover new cancer biology.

careers.petermac.org/job/MELBOURN...