Netherlands Cancer Institute

Taking over the hospital for prideweek with gendercupcakes
@nkinl.bsky.social @florencevb.bsky.social #diversity

Last week we proudly hosted the annual meeting and summer school of EMERALD PhD Programme for MDs. This international EU-life program aims to help bridge the gap between laboratory research and clinical practice.

#PhD4MDs #PhysicianScientists #BridgeTheGap #research #clinicalpractice

Cancer researcher Karin de Visser is to receive the Josephine Nefkens Prize 2025 on November 4. This triennial award recognizes exceptional cancer researchers who combine scientific excellence with societal engagement. Read more ➡️ www.nki.nl/news-events/...

Scientists at the NKI have made a remarkable discovery: a new protein duo that can turn genes on and off. They have named this duo Zincore. Together, these proteins help other proteins bind more firmly to the DNA, allowing them to perform their functions more effectively www.nki.nl/news-events/...

New study shows why immunotherapy doesn’t always wipe out an entire tumor.

Even within a single tumor, cancer cells can vary in how well the immune system sees them, and that difference is written in their DNA ➡️ www.nki.nl/news-events/...

New study: Women exposed to DES before birth do not have a higher risk of breast cancer later in life. Vaginal cancer risk remains increased, but is still rare ➡️ www.nki.nl/news-events/...

High-resolution microscopy of a mesenchymal cancer cell that has been killed by inactivating the CDS2 gene. Prior to cell death, tiny lipid droplets accumulated, which are still visible as cyan-colored dots, visualized using fluorescence microscopy. The DNA of the dead cancer cells (magenta) is dispersed throughout the surrounding area. Processed image by Tim Arnoldus, Gemma Driessen and Marjolein Mertz. Legend: magenta = DNA from dead cancer, cyan = lipid droplets

In a new Nature Genetics paper our researchers identified a synthetic lethal interaction in 50% of cancers. Tumors lacking CDS1 depend entirely on CDS2. Blocking CDS2 kills cancer cells while sparing healthy tissue ➡️ www.nki.nl/news-events/...

Women with breast cancer who receive silicone implants don’t have a higher risk of symptoms linked to Breast Implant Illness. This is the conclusion of a large Dutch study involving over 6,000 women ➡️ www.nki.nl/news-events/...

🔍 A #CCE delegation visited @nkinl.bsky.social to learn more about data, digital oncology & trials. Thanks to Wilbert Zwat Michiel van der Heijden Ruud Weijer & team for the insightful discussions.

@joseptabernero.bsky.social @carmonasfj.bsky.social Elena Chavarria Irene Brana @vhio.bsky.social

The results, based on a survey of more than 2,500 cancer patients across 25 European countries, are a cause for concern:

💰 56% lost income
💰 28% saw their income drop with up to €800/month
💰 86% faced extra costs & 16% delayed or skipped care

#EuropeanFairPricingNetwork

Cancer care in europe is costing patient more than their health.

Cancer is pushing many patients in Europe in financial dire straits – even in countries with strong healthcare systems.

A new #EuropeanFairPricingNetwork study shows that patients lose income, face additional costs & skip care after diagnosis ➡️ www.nki.nl/news-events/...

Proud! 💙 Our scientific director Thijn Brummelkamp receives the Spinoza Prize, a prize for scientists who belong to the best researchers worldwide. A wonderful recognition for his groundbreaking research.

Congrats Thijn! 🎉 @thijnbrummel.bsky.social

Full article ➡️ bit.ly/40p4KnK

YouTube video by EU-LIFE EU-LIFE Science Vision Talk Contest 2025

1️⃣8️⃣ researchers
1️⃣5️⃣ performances

🎤 From rap to drama, the EU-LIFE #ScienceVision Talk Contest brought science to life like never before!

📺 Missed it or want to relive it? Watch the event's recording here: youtu.be/iqh6xNYsqkM?...

🎥 @ceitec.eu

Congratulations Karin!

Extremely grateful to be granted a two year post-doctoral fellowship by @embo.org to study the earliest phases of mutant to malignant cell transition during breast cancer initiation using intravital microscopy. Thank to @vanrheenenlab.bsky.social for the immense support! @nkinl.bsky.social

Congratulations Hans!

🎓 PhD student Iris Nederlof found that immunotherapy can lead to complete tumor disappearance in a small group of patients with triple-negative breast cancer. @amsterdamumc.bsky.social ➡️ www.nki.nl/news-events/...

Today, these amazing NKI researchers are pushing their limits by climbing the Alpe d’Huez. Go for it lovely people! We are proud to see so many of you dedicate your time and effort to supporting cancer research.
With @oncodeinstitute.bsky.social

#AlpedHuZes #cancerresearch #ad6 #NKI

🎓 Breast reconstruction can be performed immediately after surgery, even if radiation therapy is still required, concludes PhD candidate Merel Kooijman
www.nki.nl/news-events/...

We’re proud that John Haanen @haanenjohn.bsky.social has been selected as a candidate for Chair of the ESMO Nomination Committee.

A great recognition of his dedication and expertise.
#ESMO #ESMOMembers

Do you want to learn more about our animal research? Check out this insightful article from our magazine: www.nki.nl/media/w1dlfb... #BOARD25

“It was bizarre to have my own DNA analyzed for genes I’ve been studying for so long.” Time for a conversation with group leader Hein te Riele, in preparation for his retirement ➡️ bit.ly/44V9d4N

The research is financially supported by KWF Dutch Cancer Society.
#NKI #research

🌟 The very first NKI Early Cancer Detection Conference 2025 took place this week, and we’re still buzzing with energy and inspiration. "During this conference we built a community for early cancer detection. From now on, it is: YES!"

Want to learn more?➡️ nkicecd.nl/conference
#EarlyCancerDetection

Gerrit Meijer from the @su2cscience.bsky.social-#KWF MEDOCC team presented the Team’s work in developing the multi-target FIT test for colorectal cancer at the @nkinl.bsky.social Early Cancer Detection Conference #StandUpToCancer #NetherlandsCancerInstitute #colorectalcancer

No unfortunately not. The presentations will not be available online

Day 2 of the NKI Early cancer Detection conference is off to a great start with a keynote from David Crosby @cancerresearchuk.org

Predicting gene expression from DNA sequence using deep learning models - Nature Reviews Genetics Barbadilla-Martínez et al. review recent progress in deep-learning-based sequence-to-expression models, which predict gene expression levels solely from DNA sequence. These models are providing new in...

Predicting gene expression from DNA sequence using deep learning models go.nature.com/3F8r0Li #Review by Lucía Barbadilla-Martínez, Noud Klaassen, Bas van Steensel & Jeroen de Ridder @nkinl.bsky.social @umcutrecht.bsky.social

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations - PubMed In summary, we identify a complex genomic-epigenomic interplay in EC development and progression, altering 3D genome organization to enhance expression of the critical driver ERα.

Check out our latest paper! Out now in Genome Biology! Many thanks to all coauthors for their invaluable contributions on this lengthy journey pubmed.ncbi.nlm.nih.gov/40346709/

Seven years of research into DCIS, funded by @cancergrand.bsky.social and Dutch Cancer Society, delivered crucial breakthroughs: more personalized care, fewer unnecessary treatments and a better quality of life for women with DCIS. Read more➡️ www.nki.nl/news-events/...
#cancerresearch #breastcancer

“Researchers are already under great pressure. Responsibilities for #sustainability should primarily lie with institutions,” said Henri van Luenen, representative of the Netherlands Cancer Institute @nkinl.bsky.social and EU-LIFE ⬇️

#EuropeanResearch #ResearchCareers #EUcompetitiveness