Roles of Extracellular Superoxide Dismutase in Regulating Cell Migration and Vesicle Trafficking in Dictyostelium and Mammalian Cells Superoxide dismutases (SODs) are key regulators of reactive oxygen species (ROS) and redox balance. Although intracellular SODs have been extensively studied, growing attention has been directed towa....

REVIEW ARTICLE
Roles of Extracellular Superoxide Dismutase in Regulating Cell Migration and Vesicle Trafficking in Dictyostelium and Mammalian Cells
by Lou W. Kim
onlinelibrary.wiley.com/doi/10.1111/...

Expression of hox Genes and Genes Related to Limb Development During the Homeotic Transformation of Tails Into Limbs Induced by Vitamin A in the Anuran Rana ornativentris To investigate the molecular mechanisms underlying ectopic limb development, we quantified the expression of genes related to normal limb positioning and development. We observed the downregulation o...

Expression of hox Genes and Genes Related to Limb Development During the Homeotic Transformation of Tails Into Limbs Induced by Vitamin A in the Anuran Rana ornativentris
by Sho Morioka, Yoshio Yaoita, Keisuke Nakajima, Nobuaki Furuno, Ichiro Tazawa
onlinelibrary.wiley.com/doi/10.1111/...

Fate and Specification of the Ventral Endoderm in and Outside the Foregut of the Avian Embryo at 9–12 Somite Stage The fate and specification of the endoderm lining the ventral foregut and outside the foregut cranial to the anterior intestinal portal of the 9–12 somite stage avian embryo were analyzed to determin...

Fate and Specification of the Ventral Endoderm in and Outside the Foregut of the Avian Embryo at 9–12 Somite Stage
by Susumu Matsushita, Koko Urase
onlinelibrary.wiley.com/doi/10.1111/...

Cover Photograph: Stage TK9 embryo of the Chinese soft-shelled turtle (Pelodiscus sinensis) observed with a stereomicroscope. The embryo visible in the center shows segmented somite structures extending from the head to the tail (Courtesy of Dr. Naoki Irie, The Graduate University for Advanced Studies, SOKENDAI, not in this issue).

DGD Vol. 67 (8) was released!
Cover Photo: Stage TK9 embryo of the Chinese soft-shelled turtle (Pelodiscus sinensis) observed with a stereomicroscope. The embryo visible in the center shows segmented somite structures extending from the head to the tail.
onlinelibrary.wiley.com/toc/1440169x...

今月含めこの半年で独立または独立後栄転された発生生物学関連の研究者です。皆様おめでとうございます:お祝い:
佐久間知佐子 理研ECL www.riken.jp/research/lab...
中山 尚美　OIST www.oist.jp/ja/research/...
あくまでこちらが把握している情報です。他にご存じでしたらリプで追加お願いします🙇🙇‍♂️🙇‍♀️

Sir John Gurdon 追悼 　上野直人
x.gd/6J7GX
Sir John was a thoughtful and calm scholar, yet when it came to scientific discussions, he spoke with remarkable enthusiasm and passion. Although he was a great scientist, I will never forget the innocent, boyish smile that he would occasionally show.　(抜粋）

Histone Demethylation Activity of UTX Contributes to the Regulation of Steroid Biosynthesis Genes in Embryonic Gonads but Is Dispensable for Gonadal Sex Determination Mammalian sex is determined by the presence or absence of a Y chromosome. The sex-specific features of each cell and tissue in the body then develop in response to the sex hormones secreted by the di...

Histone Demethylation Activity of UTX Contributes to the Regulation of Steroid Biosynthesis Genes in Embryonic Gonads but Is Dispensable for Gonadal Sex Determination
by M. Kojima, M. Fujita, T. Iwamori, R. Honda, K. Shima, Y. Araki, T. Tsuhako, N. Iwamori
onlinelibrary.wiley.com/doi/full/10....

Super‐Enhancer‐Mediated DLX5 Activation Defines Regulatory Mechanisms in Human Embryonic Stem Cell‐Derived Osteoblasts Osteoblast differentiation is essential for skeletal development and homeostasis. Although bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) are commonly used to study osteoblast different...

Super‐Enhancer‐Mediated DLX5 Activation Defines Regulatory Mechanisms in Human Embryonic Stem Cell‐Derived Osteoblasts
by Shinse Fujita, Shoichiro Tani, Hiroyuki Okada, Taku Saito, Sakae Tanaka, Shinsuke Ohba, Ung-il Chung, Hironori Hojo
onlinelibrary.wiley.com/doi/10.1111/...

Cell Tracing by a Multicolor Reporter Transgenic Iberian Ribbed Newt Pleurodeles waltl Cell tracing is an essential method for deciphering cellular processes during organ regeneration. We generated transgenic Iberian ribbed newts carrying the multicolor reporter Brainbow3.0 cassette un...

Cell Tracing by a Multicolor Reporter Transgenic Iberian Ribbed Newt Pleurodeles waltl
by Shinichi Hayashi, Ryohei Seki-Omura, Yuki Sato, Souichi Oe, Taro Koike, Yousuke Nakano, Hikaru Iwashita, Yukie Hirahara, Masaaki Kitada
onlinelibrary.wiley.com/doi/10.1111/...

Integrating Tissue and Cytoplasmic Rigidity Transitions During Morphogenesis Multicellular organisms generate organizational complexity through morphogenesis, in which mechanical forces orchestrate the movements and deformations of cells and tissues, while chemical signals re...

REVIEW ARTICLE
Integrating Tissue and Cytoplasmic Rigidity Transitions During Morphogenesis
by Sameer Thukral, Bipasha Dey, Yu-Chiun Wang
onlinelibrary.wiley.com/doi/10.1111/...

DGD Vol. 67 (7) was released!
Cover Photo:F1 fertilized eggs of Brainbow3.0 reporter transgenic Iberian ribbed newts were injected pCS2-Cre expression vector and mOrange2 was randomly recombined to EGFP and mKate2 in the tail at 10 days after fertilization
onlinelibrary.wiley.com/toc/1440169x...

Unraveling the regulative development and molecular mechanisms of identical sea urchin twins - Nature Communications Experiments from over a century ago showed that dividing sea urchin embryos at the 2-cell stage yields two embryos, but the mechanisms of this phenomenon have not been shown. Here, they show that thes...

筑波大学下田臨海の谷口研（@urchin_lab）
筆頭は元Dの鈴木さん（現USAでポスドク）。顕微鏡下での分割・ライブ観察・ノックダウンを積み重ね、がんばった成果です
www.nature.com/articles/s41...

Unraveling the regulative development and molecular mechanisms of identical sea urchin twins - Nature Communications Experiments from over a century ago showed that dividing sea urchin embryos at the 2-cell stage yields two embryos, but the mechanisms of this phenomenon have not been shown. Here, they show that thes...

ヒトやウニなどは二細胞胚でばらばらになると双子になります。この場合も同じように発生するのでしょうか？ウニの場合、球状に発生する正常胚と異なり、半分胚はシート状→カップ状→球状へと“自律的“に変形するのに伴い、それまでの「前」と「後」が接触します。すると、「後」で Wnt/β-カテニンが一過的に“再点火“し、新しい「前」が「後」の対極に再配置され、最終的に「半分」から“完全な胚“が再構築されます。つまり、正常胚で使われる既存の仕組みを再利用して軸情報を再編成する——これが双生児が正常個体に育つ理由の一端です。（@urchin_lab）
www.nature.com/articles/s41...

YouTube video by 日本発生生物学会公式チャンネル 「海外独立、そして宇宙への挑戦」 明楽隆志博士 第56回発生生物学会大会キャリアパスランチョンセミナー

第５６回大会キャリアパスセミナーの動画です。アメリカNIHにて研究室を主宰し、さらにJAXAの宇宙飛行士選抜試験の最終候補にまでなられた明楽隆志先生に、ご自身の研究内容とエキサイティングなキャリアに関してお話しいただきました。ぜひご覧ください！
www.youtube.com/watch?v=cBll...

YouTube video by 日本発生生物学会公式チャンネル 「イノベーションの再生に向けて」山口英一博士 第54回発生生物学会大会キャリアパスランチョンセミナー

JSDB2021のキャリアパスセミナー、山口栄一先生による「イノベーションの再生に向けて―「知」を「価値」に変える」の講演動画です。異常な論文減少など厳しい現状の振り返りのあとには新たな希望が。長期的な視点が大事。
www.youtube.com/watch?v=skXy...

YouTube video by 日本発生生物学会公式チャンネル 「謎解きを楽しもう」竹市雅俊博士 第57回発生生物学会大会教育講演

こちらが京都年会での竹市博士の日本語での教育講演です。学生時代に名古屋大〜京大で水晶体の研究をしていたころの話、カーネギーでのトリプシン溶液の組成の違いに気づいた瞬間、次世代へのメッセージと、盛りだくさんの内容です。
www.youtube.com/watch?v=zsZy...

JSDB_office

ひっそりと実はJSDB Youtubeチャネル始まっています。今の所のコンテンツは熊本年会、京都年会での竹市博士の学会の教育講演およびキャリアパスセミナーの動画ですが今後充実させていく予定です。乞うご期待！
www.youtube.com/@JSDB_office

第2回（2025年度）JSDB Frontiers Prizeの受賞者です。おめでとうございます！（ポスト遅くなり申し訳ありません🙇）
奥田覚 （金沢大学) @MechgenLab
関根清薫（東京科学大学)
jsdb.jp/blog/article...

海外便り№18　山川隼平さん (Institute of Zoology and Evolutionary Research Friedrich Schiller University Jena)
www.jsdb.jp/blog/article...

日本発生生物学会(JSDB)公式 Blueskyアカウントです。
学会HP www.jsdb.jp
X account x.com/_JSDB_
DGD is the official journal. onlinelibrary.wiley.com/journal/1440...