Melissa E. Murray

Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration Murray et al. introduce “transformative neuropathology” through dynamic, technology-integrated approaches to accelerate tissue-based discoveries and offer actionable strategies to strengthen brain ban...

Why some people have more fit brain cells at 90 when others’ start dying at their 30s? Hard to say! It is hard to study because human 🧠 is the least accessible.

@drneurochic.bsky.social et al discuss how to accelerate biomedical discoveries in brain health via transformative neuropathology.

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Every day is #InternationalWolfDay in our eyes, but today’s a great reminder of how amazing wolves are! 🐺 Support wolf recovery and conservation by donating or advocating for stronger protections. 🌎🐾

Learn more about ways to make an impact: nywolf.org

Interested to see how advanced microscopy holds the power to transform our understanding of therapeutics🔬🧠…come see our latest work. #AAIC25

Hall G session 2-3.30 pm integrative neuropathology in ADRD at 2.20 pm sharp

@drneurochic.bsky.social

@alzassociation.bsky.social #GlobalImmersionExperience reception at Thompson Landry Gallery #Toronto

#USPOINTER study #sciencerockstars report #structuredlifestyleintervention improves #cognitiveperformance 🤓💪🏼🥳💜🧠 #ENDALZ

NEWSFLASH #2: @alzassociation.bsky.social commits over $40M to translate the positive outcomes of #USPOINTER #structuredlifestyleintervention to preserve your 🧠 💜 # ENDALZ 💪🏼 from global to local.

Incredible achievement! Congratulations!

You can still be a grown a** adult and have an "I forgot my homework nightmare" ...There I sat in an audience and they call me as the next speaker and also from stage ask where my talk was😱

double booked today for two talks might have something to do with it😆 I'm excited though and pptx ready 💪

Thank you all for being great fan ❤

The Neurofibrillary Tangle Maturity Scale: A Novel Framework for Tangle Pathology Evaluation in Alzheimer's Disease Neurofibrillary tangles are dynamic neuropathologic hallmarks of Alzheimer's disease with a hypothesized lifespan morphologically-defined by three maturity levels: pretangles, mature tangles, and ghos...

🧠 New preprint alert! We are excited to present the neurofibrillary tangle maturity scale, which integrates tangle maturity scores of pretangles, mature tangles, and ghost tangles to summarize tangle maturity predilection in the tissue. @drneurochic.bsky.social
www.biorxiv.org/content/10.1...

Oh that is definitely frameable, would also consider it fridge worthy with just the right magnet 🤩

Models of autoantibody mediated diseases: actively nearing the human gold standard Human autoantibody-mediated diseases associated with a single autoantigenic target provide several valuable opportunities for precision medicine.1 The impl

academic.oup.com/brain/articl...

My editorial on an actively immunised mouse model of NMDAR antibody encephalitis. Please note my scepticism of clinical trials in this field, towards the end!

Nominate a deserving early-career investigator today for a chance to attend #CCAD2026. If selected, they will compete for a $100,000, 2-year grant from #NewVisionResearch!

View nomination criteria here 👉 newvisionresearch.org/ccad-2026/

Nominate here 👉 airtable.com/appjJE7FUGZY...

A picture by edutopia has an older woman with gray hair and an aqua sweater smiling. The quote is, "You cannot get through a single day without having an impact on the world around you. What you do makes a difference, and you have to decide what kind of difference you want to make." -Jane Goodall

What you do makes a difference.
💚🩷 -E
#GoodNews🏆
#GoodNews 🏆

This is so exciting, can't wait to read!

Read our latest review article out in @thelancetneuro.bsky.social if you want to know more about CSF transport across the different compartments of the brain-meningeal border and its importance for neurological diseases with strong neuroimmune components 😉
authors.elsevier.com/a/1l7l75FFzL...

Computational Psychiatry Course Zurich An educational course about computational psychiatry from UZH & ETH Zurich.

Learn about (generative) modeling in #ComputationalPsychiatry by attending the #CPCZurich2025.
The BEST course for learning about different models (incl. tutorials), best practices, math backgrounds, and showcase your research in the poster session:
www.translationalneuromodeling.org/cpcourse/

Curse of Neuroanatomy Training Part 4. Tessellation of Mona Lisa, but looks like gyri to us. Thanks to Dr. Jeff Browndyke. Original post by Kevin Atkinson Mathematical Tiling and Tessellation. #neuroskyence

Oh that was my very first thought, look at that cool gyral maze 🤩 perspective reveals though just how absolutely beautiful!

ATTENTION

New crowdsourced site collecting and sharing stories of public impact of research

publicusaresearchbenefits.com

Take a look and consider contributing. Let's make this as powerful as possible!

quite extraordinary story. Sometimes I think it’s the weird people that will save the world,

Oh I have no doubt. I think the more and more we shift from considering individuals as outliers and see how they help to inform medicine and science, The faster we'll be able to tackle all biomedical mysteries. Great find!

Nooooo😂😂😂

Today a pupal #Drosophila #Brain (40 h APF)
for #fluorescencefriday.

🔵 Actin
🟠🟡 Anti-E-Cad
depth-coded color

I have 1 million versions of this picture, in which I tried different LUTs. I will put some in the comments!

#microscopy #cellbio #neuroscience #insect

Redefining CNS immune privilege - Nature Reviews Immunology In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to involve isolation of the central ner...

Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems.

@jonykipnis.bsky.social
www.nature.com/articles/s41...

Oh my goodness I love it, there was once this whole skit on cool guys don't look at explosions...But apparently Danny DeVito emanates from them 😍

BEAUTIFUL and really loving the explanations 👏👏👏

Microscopy image of mmunohistochemistry to label tyrosine hydroxylase in human stems cells that are being differentiated

For #FluorescenceFriday - new experiments that I am really excited for! Really pretty tyrosine hydroxylase (TH) 🟢 labeling in human induced pluripotent stem cells that are differentiating into locus coeruleus-like cells. Image credit to the @lieberinstitute.bsky.social Imaging Development team 🧠🧪🔵

This is such a big deal, congratulations 👏👏👏

So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠

🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this ~5min survey: alz.surveymonkey.com/r/923BTQK