Carlson Alexander

Check out our article where we identified a chiral lanthanide probe for absolute temperature mapping by MRSI. Thanks to Peter Harvey and Galina for the MRI support. Thanks to Nicola for the guidance alongside DP pubs.acs.org/doi/10.1021/cb…

Check out our article where we identified a chiral lanthanide probe for absolute temperature mapping by MRSI. Thanks to Peter Harvey and Galina for the MRI support. Thanks to Nicola for the guidance alongside DP pubs.acs.org/doi/10.1021/cb…

Interested in luminescent lanthanides, check out our latest work where we look at a series of emissive Eu(III) probes for cellular imaging, alongside Bonnie and Michelle - led by DP @chemcomm.rsc.org
share.google/1eSZOaUzhWan...

#NMRchat Macrocyclic Transition-Metal Parashift Complexes for MRI at Clinical and Pre-clinical Magnetic Fields http://pubs.rsc.org/en/Content/ArticleLanding/2025/DT/D5DT01149C

Link to the article below
pubs.rsc.org/en/content/a...

Check out our latest work on macrocyclic Transition Metal Complexes as Parashift probes for MRI @daltontrans.rsc.org
pubs.rsc.org/en/content/art… alongside Chowan Ashok, Daniel Bowdery, Galina Pavlovskaya, and Peter Harvey, led by Nicola Rogers

check out this comprehensive and insightful review of lanthanide luminescent complexes in biomedical research from ‪@pikramenougroup.bsky.social‬ and colleagues!

Luminescent Lanthanides in Biorelated Applications: From Molecules to Nanoparticles and Diagnostic Probes to Therapeutics Lanthanides are particularly effective in their clinical applications in magnetic resonance imaging and diagnostic assays. They have open-shell 4f electrons that give rise to characteristic narrow, line-like emission which is unique from other fluorescent probes in biological systems. Lanthanide luminescence signal offers selection of detection pathways based on the choice of the ion from the visible to the near-infrared with long luminescence lifetimes that lend themselves to time-resolved measurements for optical multiplexing detection schemes and novel bioimaging applications. The delivery of lanthanide agents in cells allows localized bioresponsive activity for novel therapies. Detection in the near-infrared region of the spectrum coupled with technological advances in microscopies opens new avenues for deep-tissue imaging and surgical interventions. This review focuses on the different ways in which lanthanide luminescence can be exploited in nucleic acid and enzyme detection, anion recognition, cellular imaging, tissue imaging, and photoinduced therapeutic applications. We have focused on the hierarchy of designs that include luminescent lanthanides as probes in biology considering coordination complexes, multimetallic lanthanide systems to metal–organic frameworks and nanoparticles highlighting the different strategies in downshifting, and upconversion revealing some of the opportunities and challenges that offer potential for further development in the field.

Interested in luminescent lanthanides for bio-related applications? Check out our review pubs.acs.org/doi/10.1021/...
@uobchemistry.bsky.social

Luminescent Lanthanides in Biorelated Applications: From Molecules to Nanoparticles and Diagnostic Probes to Therapeutics Lanthanides are particularly effective in their clinical applications in magnetic resonance imaging and diagnostic assays. They have open-shell 4f electrons that give rise to characteristic narrow, line-like emission which is unique from other fluorescent probes in biological systems. Lanthanide luminescence signal offers selection of detection pathways based on the choice of the ion from the visible to the near-infrared with long luminescence lifetimes that lend themselves to time-resolved measurements for optical multiplexing detection schemes and novel bioimaging applications. The delivery of lanthanide agents in cells allows localized bioresponsive activity for novel therapies. Detection in the near-infrared region of the spectrum coupled with technological advances in microscopies opens new avenues for deep-tissue imaging and surgical interventions. This review focuses on the different ways in which lanthanide luminescence can be exploited in nucleic acid and enzyme detection, anion recognition, cellular imaging, tissue imaging, and photoinduced therapeutic applications. We have focused on the hierarchy of designs that include luminescent lanthanides as probes in biology considering coordination complexes, multimetallic lanthanide systems to metal–organic frameworks and nanoparticles highlighting the different strategies in downshifting, and upconversion revealing some of the opportunities and challenges that offer potential for further development in the field.

pubs.acs.org/doi/10.1021/...

Luminescent Lanthanides in Biorelated Applications: From Molecules to Nanoparticles and Diagnostic Probes to Therapeutics Lanthanides are particularly effective in their clinical applications in magnetic resonance imaging and diagnostic assays. They have open-shell 4f electrons that give rise to characteristic narrow, line-like emission which is unique from other fluorescent probes in biological systems. Lanthanide luminescence signal offers selection of detection pathways based on the choice of the ion from the visible to the near-infrared with long luminescence lifetimes that lend themselves to time-resolved measurements for optical multiplexing detection schemes and novel bioimaging applications. The delivery of lanthanide agents in cells allows localized bioresponsive activity for novel therapies. Detection in the near-infrared region of the spectrum coupled with technological advances in microscopies opens new avenues for deep-tissue imaging and surgical interventions. This review focuses on the different ways in which lanthanide luminescence can be exploited in nucleic acid and enzyme detection, anion recognition, cellular imaging, tissue imaging, and photoinduced therapeutic applications. We have focused on the hierarchy of designs that include luminescent lanthanides as probes in biology considering coordination complexes, multimetallic lanthanide systems to metal–organic frameworks and nanoparticles highlighting the different strategies in downshifting, and upconversion revealing some of the opportunities and challenges that offer potential for further development in the field.

pubs.acs.org/doi/10.1021/...

Interested in luminescent lanthanides for bio-related applications - Please check out our review pubs.acs.org/doi/10.1021/ac… written alongside Zhillin Guo, Pete Glover, Steve Faulkner, and led by Zoe Pikramenou

a beam of green light is shining on a black background ALT: a beam of green light is shining on a black background

Who wants to come and work with our group @oxfordchemistry.bsky.social on photoswitches and photopharmacology 🙋‍♀️🙋🏻🙋‍♂️

Apply for our open #chempostdoc position now! Deadline 28th Feb. Reposts appreciated #Chemsky

my.corehr.com/pls/uoxrecru...

Dark green / black crystals inside a glass tube.

Happy to announce two funded #PhD studentships for aspiring synthetic chemists to do some f-element molecule making.

(1) High oxidation states; (2) Tuneable electronic structures for qubits.

See: www.capgoodwin.com/pages/positi... for details, and below for both FindAPhD links.