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Nico Dosenbach

@ndosenbach.bsky.social

David M. & Tracy S. Holtzman Professor, Neurology @ WashU School of Medicine; precision neuroimaging, network plasticity, BWAS ≠ fMRI, action mode; #neuroscience #neurology #openscience #science dosenbachlab.wustl.edu

1,564 Followers  |  2,189 Following  |  77 Posts  |  Joined: 29.11.2023  |  2.1618

Latest posts by ndosenbach.bsky.social on Bluesky

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Associate or Senior Editor, Nature Biological, Clinical, and Social Sciences - New York City, New York (US) job with Springer Nature Ltd | 12848260 Title: Associate or Senior Editor, Nature Biological, Clinical, and Social Sciences Organization: Nature Portfolio Locations: New York, Jersey City...

Do you have a background in applied #AI and an interest in joining @nature.com's editorial team? If so, consider applying! www.nature.com/naturecareer...

29.10.2025 16:35 — 👍 3    🔁 2    💬 0    📌 0
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AI discovers learning algorithm that outperforms those designed by humans An artificial-intelligence algorithm that discovers its own way to learn achieves state-of-the-art performance, including on some tasks it had never encountered before.

Did you know that AI can figure out its own way to learn, and that its way is better than one designed by humans? Read more in a @nature.com N&V (and the original paper is in the comment) 🧪 www.nature.com/articles/d41...

24.10.2025 13:18 — 👍 6    🔁 2    💬 2    📌 0

Thank you @caterinagratton.bsky.social for inviting me to contribute to this! Fascinating to dive into the causes and consequences of individual differences in brain organization.

16.10.2025 15:59 — 👍 12    🔁 2    💬 0    📌 0
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Dense Phenotyping of Human Brain Network Organization Using Precision fMRI The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...

Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
🧵👇

16.10.2025 15:00 — 👍 75    🔁 41    💬 1    📌 3

Important consideration to better model neuroimaging data

07.10.2025 19:37 — 👍 5    🔁 1    💬 0    📌 0

Check out some compelling and timely work by @nasiametoki.bsky.social on sex vs gender differences in the developing adolescent brain!

07.10.2025 19:56 — 👍 3    🔁 2    💬 0    📌 0
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Is resting-state functional connectivity (rsFC), cortical thickness (CT), or cortical volume more effective at capturing sex and gender differences in the brains of preadolescents?

Check out our new article (doi.org/10.1016/j.dc...) now out in Developmental Cognitive Neuroscience.

07.10.2025 19:02 — 👍 13    🔁 6    💬 4    📌 2

That's going to be very useful !!

30.09.2025 19:48 — 👍 4    🔁 1    💬 0    📌 0

This is such a fantastic resource and paper! @benjaminkay.bsky.social has unrivaled tenacity for seeing this awesome project through!

Check this out and give him a follow for some of the most thoughtful, statistically rigorous, and well-executed clinical neuroimaging around.

30.09.2025 20:14 — 👍 8    🔁 1    💬 0    📌 0
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Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...

30.09.2025 19:39 — 👍 56    🔁 23    💬 1    📌 2
Baden-Württemberger Forschungsinstitute erhalten 3,6 Millionen Euro für ’Global Fellowships’

The German State of Baden-Württemberg is sponsoring 14 fellowships for researchers whose work is under political pressure in the US. Total funding for the fellowships is 3.6 million EUR. Freiburg, Konstanz and Tübingen are the participating universities.
🧪

www.myscience.de/en/news/wire...

01.10.2025 12:38 — 👍 11    🔁 10    💬 0    📌 0
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Years of hits to the head prime the brain for decline Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein.

It's accompanied by an excellent News and Views that explains how this primes the brain for decline in later years www.nature.com/articles/d41...

21.09.2025 14:21 — 👍 7    🔁 2    💬 0    📌 0
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Repeated head trauma causes neuron loss and inflammation in young athletes - Nature Repetitive head impacts from contact sports are associated with brain inflammation, vascular damage and neuron loss that are independent of hyperphosphorylated tau pathology.

I feel like this should go without saying, but repeated hits to the head can only be bad: A recent @nature.com paper describes the neuron los and inflammation caused by repeated head trauma in young athletes 🧪 www.nature.com/articles/s41...

21.09.2025 14:21 — 👍 18    🔁 8    💬 1    📌 0
Make trains great again — for the sake of people and the planet As railways enter their third century of service, research must support their renaissance for more-sustainable travel that supports human development.

I love taking trains so was so glad to see @nature.com's recent editorial advocating for sustainable rail travel www.nature.com/articles/d41...

22.09.2025 13:51 — 👍 6    🔁 1    💬 0    📌 0
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DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning - Nature A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing t...

I feel very proud to be part of @nature.com, and to have colleagues who handled this excellent #DeepSeek paper that describes DeepSeek-R1, because it's the first widely used commercial LLM that has been published in a peer-reviewed journal 🧪 www.nature.com/articles/s41...

22.09.2025 18:12 — 👍 11    🔁 2    💬 1    📌 0
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Countrywide natural experiment links built environment to physical activity - Nature By analysing the smartphone data of 2,112,288 participants, in particular observing and comparing the activity of the same individual in two different environments, we find that increases in the walka...

Did you know that people who move to more walkable cities in the US end up walking more? This seems obvious, but is quite solid evidence for the influence of the built environment on human activity and well-being. Read more in the @nature.com paper here: www.nature.com/articles/s41...

16.09.2025 15:30 — 👍 58    🔁 14    💬 0    📌 2
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Heatwaves linked to carbon emissions from specific companies Nearly one-quarter of heatwaves would have been ‘virtually impossible’ without global warming — and can be attributed to the emissions of individual energy producers.

Did you know that scientists have been able to link heatwaves to the carbon emissions from specific companies? Read more in @nature.com's recent new story 🧪 www.nature.com/articles/d41...

15.09.2025 16:49 — 👍 4    🔁 1    💬 1    📌 0
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Pesticides are drifting above us, and for diseases like Parkinson’s and Alzheimer’s, drifting 'chemical filled clouds' will be bad news for everyone. A new study revealed that pesticides are not just in the soil and water, they are traveling long distances and accumulating in cloud water.

14.09.2025 13:50 — 👍 12    🔁 5    💬 0    📌 0
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An abiding mystery of the French Revolution is solved — by epidemiology The period of panic and unrest called the Great Fear was triggered by deliberately spread rumours, according to methods borrowed from pandemic playbooks.

or in our news coverage www.nature.com/articles/d41...

11.09.2025 12:50 — 👍 6    🔁 2    💬 0    📌 0
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Viral spread: how rumours surged in revolutionary France Hear the biggest stories from the world of science | 27 August 2025

Hear more about this work on the nature podcast www.nature.com/articles/d41...

11.09.2025 12:50 — 👍 5    🔁 2    💬 1    📌 0
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Epidemiology models explain rumour spreading during France’s Great Fear of 1789 - Nature Epidemiological methods are used to show that the Great Fear of 1789, a series of peasant insurrections in rural revolutionary France, was driven by deliberate political action rather than spontaneous...

How did rumors spread in revolutionary France? A recent @nature paper take an epidemiological approach to understand the spread of the "great fear" in France... and is an example of the type of social science work that we are now publishing www.nature.com/articles/s41...

11.09.2025 12:50 — 👍 9    🔁 4    💬 1    📌 0
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Chronic pain is one of the most under-recognized burdens for folks with Parkinson’s disease. It is time we bring chronic pain in PD out of the shadows and address it as a central part of a care plan. Ogonowski and colleagues tackle this topic head on in a new article in Annals CTN.

09.09.2025 12:32 — 👍 7    🔁 4    💬 0    📌 0
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Q&A with Nico U.F. Dosenbach and Roselyne Chauvin Nico U.F. Dosenbach and Roselyne Chauvin spoke with Cell Reports about their recent paper, in which they observed subcortical plasticity in humans following a 2-week arm/hand-casting paradigm with dai...

Want to know the behind the scenes of the "Disuse-driven plasticity in the human thalamus and
putamen" paper? discover @ndosenbach.bsky.social and I interview by @cp-cellreports.bsky.social

www.cell.com/cell-reports...

09.09.2025 15:38 — 👍 18    🔁 5    💬 1    📌 0
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How the brain’s amygdala reacts when making decisions to avoid losses Neural noise increases before choosing to explore other options when faced with possible adverse consequences.

And for those with less time, the authors put together a short summary that explains the study, it's contributions, and some opinions of experts in the field: www.nature.com/articles/d41...

05.09.2025 20:09 — 👍 5    🔁 2    💬 1    📌 0
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Rate and noise in human amygdala drive increased exploration in aversive learning - Nature Human exploration is driven by two distinct neural mechanisms, a valence-independent rate signal and a valence-dependent global noise signal.

People explore unfamiliar options more when deciding how to avoid losses than when seeking gains, shows a recent paper published in @nature.com 🧪 www.nature.com/articles/s41...

05.09.2025 20:09 — 👍 14    🔁 3    💬 1    📌 0
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Neuroscience and society. Folks this is definitely an important 'thing.' We need to pay attention as technology begins to overtake society. Tune in virtually here to catch all of the great discussions this morning at the DBS Think Tank. ufl.zoom.us/webinar/regi... @parkinsondotorg.bsky.social

03.09.2025 12:27 — 👍 3    🔁 1    💬 0    📌 0
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A new study in Movement Disorders highlights the role of the somato-cognitive action network or SCAN in focal dystonia. Today marks the start of the DBS Tank and I will be asking Nico Dosenbach: When you keynoted the DBS Think Tank a few short years ago, did you imagine the impact of SCAN imaging?

02.09.2025 13:28 — 👍 10    🔁 3    💬 0    📌 0
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Ray and I have received tons of requests by email and text for the link to listen to our 1 hour interview that aired live on NPR's 1A this week. THANK YOU! Here it is. We urgently need a Parkinson's Plan, and that is why we wrote the book.
the1a.org/segments/cou... @parkinsondotorg.bsky.social

21.08.2025 14:17 — 👍 7    🔁 2    💬 1    📌 0
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Somato‐Cognitive Action Network in Focal Dystonia Background The central pathology causing idiopathic focal dystonia remains unclear. The recently identified somato-cognitive action network (SCAN) has been implicated. Objective We tested whether ...

🚨 New paper alert!
Excited to share our latest work in Movement Disorders:
“Somato-Cognitive Action Network in Focal Dystonia”
👉 doi.org/10.1002/mds....

We found asynchrony between SCAN and cerebellum in different dystonia subtypes. Thread below.
#dystonia #fMRI #PrecisionFunctionalMapping #neuro

28.08.2025 16:41 — 👍 10    🔁 5    💬 1    📌 0

Oh do I understand. So full of happiness to see that Mike is doing better and has relief from the nightmare of treatment-resistant severe depression. Joy is bliss!

12.08.2025 14:09 — 👍 8    🔁 2    💬 0    📌 0

@ndosenbach is following 19 prominent accounts