@pjsaez.bsky.social
Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat. I love to study how cells walk & talk. PI of the @cellcommlab.bsky.social #CellMigration #CellComm #calciumsignaling #organelles 🧪🔬
Hot from the #preprint
Leukocyte + #CellMigration + physics = cool
Microtubules enable torque-based steering during dendritic cell migration.
Actomyosin contractility is required for noise-modulation strategy used by neutrophils.
Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Hopefully, the only problem is:
papers in my head > papers under preparation >>> papers in real life
😂🤦🏽🤷🏽♂️
Beautiful work, congrats !
We are doing a lot with the same cells/models, a lot of opened questions.
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Great question! I know that paper from very close as I was there when they published it 😂
I took some time bc I went to check the data in case I have done it, but could find it. From heart if I remember right there was an increase probably bc actin dynamics are boosted
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
Felicidades querido JuanMa !
El Breaking lab, o el lab FLIPado (de FLIPR) será enorme...
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ICYMI - In September, we co-hosted a mini-symposium with the Membrane Trafficking webinar series. You can view the recordings of the talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and the keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
14.11.2025 14:33 — 👍 7 🔁 3 💬 0 📌 0
Screenshot of the FocalPlane Cell Biology events calendar
To help you plan your conference travel for 2026, we’ve been busy updating our #CellBiology events calendar on FocalPlane.
If we are missing your event, feel free to add it to the calendar or reach out to our Community Manager @helenzsci.bsky.social.
focalplane.biologists.com/cell-biology...
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Registration is OPEN for our Spring meeting: Dynamic Cell VI
🗓️ 21st-26th April 2026
📍Reading, UK
Co-organised with @biochemsoc.bsky.social @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology
Register here:
www.eventsforce.net/biochemsoc/f...
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
We hiring! Please share this post with your talented ECRs
We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome
Based at @lmcb-ucl.bsky.social at University College London
Apply here:
www.jobs.ac.uk/job/DPD418/r...
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience
recruiting.paylocity.com/recruiting/j...
👊🏽👊🏽 = puñito puñito
29.10.2025 21:24 — 👍 0 🔁 0 💬 0 📌 0
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
27.10.2025 07:00 — 👍 32 🔁 20 💬 0 📌 3
Kudos to @eliasbarrigalab.bsky.social for the Innovation DGZ Prize for his work on #CellMigration
A great Chilean 🇨🇱 in #STEM 💪🏽🔥
@dgz.bsky.social #DGZ50
When your email box is so bad that every time day you are in the "my dog eat the homework" situation...
But this email is actually a dog, that actually eats the homeworks...wtf
The future of High-Content Imaging has arrived.
-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!
See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
New preprint from our lab! ER geometry sets the tempo of neuronal bursting via Ca²⁺ store-refill—revealing selective neuronal vulnerability to ER-structure problems. Thread to follow.🧠⚡️
www.biorxiv.org/content/10.1...
#Neurodegeneration #NeuroCellBiology #Calcium #bioRxiv
Very cool, thanks for your answer. Fiji is always the best ;)
I meant more on how did you do the composite to make the coloured insets to displace to the right, etc. Maybe you used an available macro or something you did for yourself ?
Fantastic live-cell imaging and even better data visualization!
May I ask how you did it?
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Ils ont même un chanson en français 😉
Pour les petits et petites @guijacquemet.bsky.social @christlet.bsky.social @agathechaigne.bsky.social
youtu.be/nvP5YKlw9-Y?...
Do you like the @npr.org tiny desk? Try this one👇🏽
"31 minutos" was one the most viewed shows "for kids" in Latin America.
It's the Chilean 🇨🇱 version of Sesame Street with acid humour, political critic & great music played by members of actual bands!
#31minutos en #ElTiny
youtu.be/UEqTIwRrWvA?...
Epiblast Ca2+ waves propagate from the apical to basal domain. The images show selected time points from movies of E5.5 GCaMP6f embryos imaged using a ZEISS lattice light-sheet 7 microscope. Top row: An example of an epiblast wave involving a large proportion of the tissue captured by imaging a volume of the embryo at 20-s intervals. A total of 9/16 embryos showed at least one epiblast Ca2+ wave. Bottom row: Faster imaging at 5-s interval revealed that the Ca2+ wave in the epiblast can be preceded by a transient in a neighboring VE cell—this was observed in 5/19 events from 9 embryos (white arrowheads).
During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4
07.10.2025 08:18 — 👍 3 🔁 2 💬 0 📌 1
Job alert!
We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?
See also on the forum:
forum.image.sc/t/research-e...
