Pablo J. Sáez

Pablo J. Sáez

@pjsaez.bsky.social

Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat. I love to study how cells walk & talk. PI of the @cellcommlab.bsky.social #CellMigration #CellComm #calciumsignaling #organelles 🧪🔬

1,594 Followers 469 Following 240 Posts Joined Aug 2023
20 hours ago
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Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - FocalPlane Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - News

📢New behind the paper story

Using the #zebrafish retina as a model, Jaakko Lehtimäki
@jalehtimaki.bsky.social, Caren Norden
@nordenlab.bsky.social & team dissect multipolar migration in the developing brain. In this post, Jaakko takes us through their research.

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16 hours ago
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This week we are introducing neuromodulatory assembloids.

Over the past few years, many circuits and cell-cell interactions have been modeled in assembloids, but these systems have not systematically incorporated neuromodulation.

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12 hours ago

Wow, it looks fantastic !!
How many tiles for this stitching? 😱

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12 hours ago
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elmo from sesame street is surrounded by flames and smoke ALT: elmo from sesame street is surrounded by flames and smoke

You are the best !!! Very much looking forward to collaborate !!!
Eres una crack 💪🏽🔥💪🏽

To be properly celebrated in the best place of all: Zé... 😉 (I cannot say the full name to keep it protected as @christlet.bsky.social & @henriqueslab.bsky.social said)

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2 days ago
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Microscopy preprints - applications in biology - FocalPlane Microscopy preprints - applications in biology - News

Our #preprint list is now up on FocalPlane.
Start your week feeling inspired by the latest research using microscopy to answer questions in biology. Let us know if you have any recommendations for us to add.

focalplane.biologists.com/2026/03/09/m...

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6 days ago
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#Science #Physique
🔬 « Transport dans la cellule »
🖥️ Le cours du Pr Jean-François Joanny, titulaire de la chaire Matière molle et #biophysique, est terminé... mais toutes les vidéos sont à re(voir) sur notre site web !
👉 https://tinyurl.com/3wfjve5c

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1 week ago
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New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...

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1 week ago
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PhD and Postdoc Transition Program | Gilliam Fellows | HHMI The Gilliam Fellows Program supports PhD students and their faculty thesis advisors to advance cutting-edge research, facilitate the transition to postdoctoral scientist, and foster the development of...

2nd- or 3rd-year PhD student? Applications for @hhmi-science.bsky.social's #GilliamFellows Program open 9/1! Robust dissertation support, an incredible community of scientists, tailored professional development (for you *and* your faculty thesis advisor), & so much more. Bookmark bit.ly/4qQArRh!

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1 week ago
Contact/Job - Department of Molecular and Cellular Biology - UNIGE

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

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1 week ago
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Léa Marpeaux, Claire Baudouin, Gregory Emery @emery-lab.bsky.social and colleagues @umontreal.ca identify an apical supracellular actin network in epithelial cells that acts as a long-range force transmission device.

journals.biologists.com/jcs/article/...

journals.biologists.com/jcs/article/...

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1 week ago
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Imaging spotlight: PhotoFiTT - FocalPlane Imaging spotlight: PhotoFiTT - News

🔬🔦In our latest ‘Imaging spotlight’ Estibaliz Gómez de Mariscal @gomez-mariscal.bsky.social & Mario Del Rosario @mariodelr.bsky.social tell us all about PhototFiTT, the framework they developed for measuring phototoxicity in live-cell fluorescence imaging.
focalplane.biologists.com/2026/03/02/i...

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1 week ago
Apply to become a Preprint Editor
Development

We are inviting experienced researchers to apply to become Preprint Editors, a new type of editorial role responsible for handling our 'In preprints' articles and forging links with preprint literature. #prepints

Learn more and apply before 30 March 2026:
journals.biologists.com/dev/pages/pr...

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1 week ago
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We had covered the history of traction force microscopy (TFM) earlier:
bsky.app/profile/epim...

But what about applying TFM into more physiologically relevant systems, such as those in 3D?

I am @barrasa-fano.bsky.social and I'll be your guide through this thread on #3DTractionForceMicroscopy.

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2 weeks ago

One week left to register to the Bioimage Analysis with AI course in Pasteur!

This June, 1 - 5.

I give a bit more details in the thread below
👇

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2 weeks ago
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Have you produced beautiful images as part of your cell biology research?

Then enter our image competition!

bscb.org/competitions...

Deadline 31st March

Check out last year's winner 'Brainbow' by Alvaro Castano

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2 weeks ago
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🔬🔴Join us for the 9th Danish Bioimaging Symposium on May 7-8 at the Danish Cancer Institute
Don’t miss it!. Registration is now Open!
The symposium will emphasize advancing cancer research through imaging technologies.
Sections: Image Analysis, Microscope Techniques and Scientific Cancer research.

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2 weeks ago
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Microscopy preprints – new tools and techniques in imaging - FocalPlane Microscopy preprints – new tools and techniques in imaging - News

Our latest preprint list is up on FocalPlane.

This list is focussed on new tools and techniques in imaging. Let us know if you have any recommendations for us to add.

focalplane.biologists.com/2026/02/20/m...

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2 weeks ago
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Join us next Tuesday for the next @dgz.bsky.social workshop on #trafficking and EVs! Spread the word please!

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2 weeks ago
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Cell body getting taken for a ride in this early stage neuron. Microtubules🔵 and Actin🟣 labeled and imaged for 16hr on a Zeiss LSM880. Happy #FluorescenceFriday

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1 month ago
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Activities - GreenTE Activities Webinars ”MechanoBioTalks – Mechanics, Materials and Living Matter” is a webinar series supported by the GreenTE consortium and organized […]

We are happy to announce the start of the MechanoBioTalks – Mechanics, Materials and Living Matter an initiative organized by GreenTE young researchers. The aim of the webinars is to bring together researchers interested in biomechanics, biophysics and biology.
Register here: green-te.nl/activities/

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1 month ago

Looking forward to hear what you find.
Good luck

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1 month ago
Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab

2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...

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1 month ago

Very nice imaging !
It seems that some areas of the brain are somehow depleted of microglia.
Is that correct? And if so, who takes over the immunosurveillance in those regions?

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1 month ago
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Not something you see in textbooks very often: tripolar mitosis.

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1 month ago
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Microscopy preprints: bioimage analysis - FocalPlane Microscopy preprints: bioimage analysis - News

Our #preprint list is up on FocalPlane. This list focusses on the latest tools in bioimage analysis.
Let us know if you have any recommendations to add to our list.
focalplane.biologists.com/2026/02/06/m...

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1 month ago
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"The microtubule GTP-tubulin cap size is modulated during cell division" is now available on @biorxivpreprint! This video by Anna Cassidy shows the tips of growing microtubules (EB1) and DNA (histone 2B) during metaphase. #Cellbiology
www.biorxiv.org/content/10.6...

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1 month ago
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BINA STED User Group, February 12, 12 PM ET - FocalPlane BINA STED User Group, February 12, 12 PM ET -

The next @bioimagingna.bsky.social @canadabioimaging.bsky.social Nanoscopy (previously STED) User Group meeting is on 12 February from 12 pm ET. The group welcomes researchers at all levels for an open discussion on nanoscopy methods.
focalplane.biologists.com/2026/02/02/b...

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1 month ago
Fill out our community survey to help shape the future of JCS

Journal of Cell Science logo

Line drawing of a group of people with speech bubbles above their heads

After 15 years as Editor-in-chief (EiC), Michael Way @drmichaelway.bsky.social will be stepping down at the end of 2026 & we are seeking feedback from the cell biology community as part of the consultation process for appointing a new EiC.
We'd love to hear from you: www.surveymonkey.com/r/GZCC9F9

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1 month ago
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#FluorescenceFriday

Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology

New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥

Full www.sciencedirect.com/science/arti...
#microscopy #cell 🧪🔬

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1 month ago
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JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px

@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.

journals.biologists.com/jcs/article/...

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