Pablo J. Sáez

Strength in numbers: tumor cells cooperate to survive under metabolic stress

Out on today's issue! :)

www.nature.com/articles/s41...

Very cool, Melike ! Until when are you around?
I'll be there later this year, also maybe a good time to catch up with @gautamdey.bsky.social ;)

Maybe a young grandpa?
(Any consolation?)

Great image !!
Which are the staining you used here?

Fantastic images, kudos

Featured image with Krystyna Gieniec - FocalPlane Featured image with Krystyna Gieniec - News

Our featured image on this #FluorescenceFriday is a 2D culture of mouse mammary fibroblasts. The image, titled ‘Unexpected guests’ was acquired by Krystyna Gieniec.

Read our post to discover more the image and about Krystyna’s research: focalplane.biologists.com/2025/08/01/f...

If you are an "FFPE expert", could I ask you a few questions?

Let me know and I'll DM you 😊

Please RT

Head of the Cell Biology and Biophysics Unit The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Reviewer accused of stealing manuscript and publishing it as his own denies he refereed it An early-career researcher who discovered a nearly identical version of her manuscript published by the researcher who reviewed — and recommended rejecting — the work for another journal is still a…

This should have never happened...

Unscrupulous reviewer rejects a paper and then submits *a very similar story* to another journal 🤦🏽

"Incidentally", the plagiarized author is a #WomenInStem 👩🏽‍🔬

Painful but necessary read: retractionwatch.com/2025/07/25/r... @retractionwatch.com

Barely made ir for another #FluorescenceFriday

Ahhh the #Nucleus ... it never gets old.
This #cell has 2 bc why not !! It seems they are refusing to separate.

This 👇🏽 is an excellent chance to put your last work in the nucleus in this issue edited by @abbybuch.bsky.social @jcellsci.bsky.social

elmo from sesame street is standing in front of a wall of flames ALT: elmo from sesame street is standing in front of a wall of flames

Kudos to all authors, cannot wait to have a proper read.
@fadelvalle.bsky.social

Join us for the first Mechanobiology of the Nucleus conference supported by @faseborg.bsky.social. Co-organized with @lammerdinglab.bsky.social, @katemiro.bsky.social and Verena Ruprecht, the amazing program is here:
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.

#GloBIAS seminar coming up this week. We start the next miniseries on: 'Infrastructure - Best practices to build a bioimaging project starting from a user request'
with Aastha Mathur from Euro-BioImaging. To receive the link, register here: tinyurl.com/msm6ts9b if you haven't done so already.

Heartberry > strawbutt, although with p>0.051

Nice movie !! The probe used by Orion's lab or Peter's?

More of other scientific research in #microscopy and #bioimaging in their brand new website: complextissue.com
[ doi.org/10.1038/s415... ]

Tks for the invite so the @cellcommlab.bsky.social could contribute with some #CellMigration, congrats to all authors

#BskyScience #cellbio #diabetes #scicomm

#HotFromThePress !!

What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?

@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease

Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬

One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.
elifesciences.org/articles/931...

Like when _anonymous_ told me "why don't you use RGB, the *true colours* for Texas red, GFP, and DAPI?"
Sigh...
What to say.

YouTube video by Scientific American What is Scientific American?

We finally made it to Bluesky—just a few billion years after the Big Bang, and only slightly late to the party ✨🌌

We’re sharing some of our best stories from the year so far to kick off our Bluesky journey!

elmo is surrounded by flames with the word fuego written above him ALT: elmo is surrounded by flames with the word fuego written above him

Kudos Shailaja ! Good luck in your future adventures, you will do great.

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

This is why we love #cellmigration

#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.

I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !

#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬

📢 Czech BioImaging is organizing a one-week Advanced Course on Preclinical Imaging on Intravital Microscopy 🔬

💡Lectures and hands-on sessions
🗓️September 8-12, 2025
📍Prague & Brno 🇨🇿
⌛️Register by July 9⤵️
www.iem.cas.cz/en/events/ad...

Image credits to David Vondrášek

🧵 Neural networks meet cell migration in Valencia!

Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫

That's not you, he has no goatee...
👀

Post yourself from another era.

(20 years ago)

Do you know what happens if you squeeze a #cell?

If the #confinement is high, the nucleus (green) will be super tense & the compressed cells will react like this👇🏽changing their #cytoskeleton (magenta)

Full: www.science.org/doi/10.1126/...
#scicomm #microscopy #sciencesky @focalplane.bsky.social 🧪🔬

Collage of figures extracted from featured preprints

We're just putting together our next #preprint list, covering research using #microscopy to answer biological questions.

We've got a great list so far showcasing a whole host of imaging techniques, including some amazing ExM and vEM images, but we'd love to hear your recommendations!
#preprints

Calling all #mitochondriaks - register now for our webinar together with @mitotalks.bsky.social.

🗓️ Thursday 3 July 17:00 CEST, 16:00 BST, 11:00 EDT, 08:00 PDT

focalplane.biologists.com/2025/06/09/m...