DZNE research center's Avatar

DZNE research center

@dzne.science.bsky.social

Dedicated to advancing the scientific understanding of neurodegenerative diseases - from mechanisms to diagnosis, therapy, and prevention (such as AD, PD or ALS). 🔗 Imprint: https://dzne.de/en/imprint 🔗 Data Protection: https://dzne.de/en/data-protection/

1,087 Followers  |  305 Following  |  299 Posts  |  Joined: 02.11.2023
Posts Following

Posts by DZNE research center (@dzne.science.bsky.social)

Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1 C. dos Santos, Jéssica; Groenendijk, Albert L.; Ruijten, Suzanne D. E.; et al. iScience Vol. 29, no. 3, p. 114807 -

New paper out: Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1: C. dos Santos, Jéssica; Groenendijk, Albert L.; Ruijten, Suzanne D. E.; et al.
iScience Vol. 29, no. 3, p. 114807 - | Thanks for sharing #dzne #papers

07.03.2026 18:13 — 👍 1    🔁 0    💬 0    📌 0
Low number of patients qualifying for amyloid targeting immunotherapy. Jessen, Frank The journal of prevention of Alzheimer's disease Vol. 13, no. 3, p. 100516 -

New paper out: Low number of patients qualifying for amyloid targeting immunotherapy.: Jessen, Frank
The journal of prevention of Alzheimer's disease Vol. 13, no. 3, p. 100516 - | Thanks for sharing #dzne #papers

07.03.2026 13:53 — 👍 0    🔁 0    💬 0    📌 0
Dysphagia in Multiple System Atrophy Does Not Correlate with Serum Neurofilament Light Chain and Glial Fibrillary Acidic Protein. Klietz, Martin; Pannewitz-Makaj, Katharina; Baacke, Franziska; et al. Movement disorders p. mds.70092

New paper out: Dysphagia in Multiple System Atrophy Does Not Correlate with Serum Neurofilament Light Chain and Glial Fibrillary Acidic Protein.: Klietz, Martin; Pannewitz-Makaj, Katharina; Baacke, Franziska; et al.
Movement disorders p. mds.70092 | Thanks for sharing #dzne #papers

07.03.2026 10:54 — 👍 2    🔁 0    💬 0    📌 0
Quantitative susceptibility mapping of brain iron in adult ADHD. Schulze, Marcel; Autenrieth, Erik; Aslan, Behrem; et al. Frontiers in psychiatry Vol. 17, p. 1735191

New paper out: Quantitative susceptibility mapping of brain iron in adult ADHD.: Schulze, Marcel; Autenrieth, Erik; Aslan, Behrem; et al.
Frontiers in psychiatry Vol. 17, p. 1735191 | Thanks for sharing #dzne #papers

06.03.2026 18:14 — 👍 1    🔁 0    💬 0    📌 0
Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity. Konstantoulea, Katerina; Ramakers, Meine; Borrie, Sarah C; et al. Proceedings of the National Academy of Sciences of the United States of America Vol. 123, no. 10, p. e2516774123

New paper out: Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity.: Konstantoulea, Katerina; Ramakers, Meine; Borrie, Sarah C; et al.
Proceedings of the National Academy of Sciences of the United… | Thanks for sharing #dzne #papers

06.03.2026 13:53 — 👍 0    🔁 0    💬 0    📌 0
Zusammenführen, was zusammengehört: Neuropsychiatrie Spruth, Eike Jakob; Gemenetzi, Maria; Altenstein, Slawek; et al. Nervenheilkunde Vol. 45, no. 01/02, p. 10 - 11

New paper out: Zusammenführen, was zusammengehört: Neuropsychiatrie: Spruth, Eike Jakob; Gemenetzi, Maria; Altenstein, Slawek; et al.
Nervenheilkunde Vol. 45, no. 01/02, p. 10 - 11 | Thanks for sharing #dzne #papers

06.03.2026 10:53 — 👍 2    🔁 0    💬 0    📌 0
Real-Time Emotion Recognition Performance of Mobile Devices: A Detailed Analysis of Camera and TrueDepth Sensors Using Apple's ARKit. Aldenhoven, Céline Madeleine; Nissen, Leon; Heinemann, Marie; et al. Sensors Vol. 26, no. 3, p. 1060 -

New paper out: Real-Time Emotion Recognition Performance of Mobile Devices: A Detailed Analysis of Camera and TrueDepth Sensors Using Apple's ARKit.: Aldenhoven, Céline Madeleine; Nissen, Leon; Heinemann, Marie; et al.
Sensors Vol. 26, no. 3, p. 1060 - | Thanks for sharing #dzne #papers

05.03.2026 18:13 — 👍 1    🔁 0    💬 0    📌 0
Microglia-Derived Extracellular Vesicles from Alzheimer's Disease Patients Carry miRNAs Driving a Neuroinflammatory Response. Arbaciauskaite, Skaiste; Silvestri, Simona; Luo, Pingyan; et al. Molecular neurobiology Vol. 63, no. 1, p. 435

New paper out: Microglia-Derived Extracellular Vesicles from Alzheimer's Disease Patients Carry miRNAs Driving a Neuroinflammatory Response.: Arbaciauskaite, Skaiste; Silvestri, Simona; Luo, Pingyan; et al.
Molecular neurobiology Vol. 63, no. 1, p. 435 | Thanks for sharing #dzne #papers

05.03.2026 13:53 — 👍 2    🔁 0    💬 0    📌 0
Informational complexity as a neural marker of cognitive reserve. Stolp, Laura; Mandke, Kanad N; Mediano, Pedro Am; et al. Brain and cognition Vol. 193, p. 106392 -

New paper out: Informational complexity as a neural marker of cognitive reserve.: Stolp, Laura; Mandke, Kanad N; Mediano, Pedro Am; et al.
Brain and cognition Vol. 193, p. 106392 - | Thanks for sharing #dzne #papers

05.03.2026 10:53 — 👍 2    🔁 0    💬 0    📌 0
The impact of lifestyle restrictions on memory in older adults. McMaster, Jessica M V; Gellersen, Helena M; Korkki, Saana M; et al. PLOS ONE Vol. 21, no. 2, p. e0342458 -

New paper out: The impact of lifestyle restrictions on memory in older adults.: McMaster, Jessica M V; Gellersen, Helena M; Korkki, Saana M; et al.
PLOS ONE Vol. 21, no. 2, p. e0342458 - | Thanks for sharing #dzne #papers

04.03.2026 18:13 — 👍 1    🔁 0    💬 0    📌 0
Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia. Menden, Benita; Incebacak Eltemur, Rana D; Demidov, German; et al. Nature Communications Vol. 17, no. 1, p. 1698

New paper out: Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia.: Menden, Benita; Incebacak Eltemur, Rana D; Demidov, German; et al.
Nature Communications Vol. 17, no. 1, p. 1698 | Thanks for sharing #dzne #papers

04.03.2026 13:53 — 👍 1    🔁 0    💬 0    📌 0
Longitudinal modeling of Post-COVID-19 condition over three years: A machine learning approach using clinical, neuropsychological, and fluid markers. Walders, Julia; Wetz, Sophie; Costa, Ana Sofia; et al. Scientific reports Vol. 16, no. 1, p. 6517

New paper out: Longitudinal modeling of Post-COVID-19 condition over three years: A machine learning approach using clinical, neuropsychological, and fluid markers.: Walders, Julia; Wetz, Sophie; Costa, Ana Sofia; et al.
Scientific reports Vol. 16, no. 1, p. 6517 | Thanks for sharing #dzne #papers

04.03.2026 10:53 — 👍 4    🔁 0    💬 0    📌 0
Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis. Gao, Jincheng; Bader, Almke; Linder, Monika I; et al. Cell death & disease Vol. 17, no. 1, p. 180

New paper out: Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis.: Gao, Jincheng; Bader, Almke; Linder, Monika I; et al.
Cell death & disease Vol. 17, no. 1, p. 180 | Thanks for sharing #dzne #papers

01.03.2026 18:13 — 👍 3    🔁 0    💬 0    📌 0
Fear of progression in Parkinson's disease: Role of age and occupational status. D'Souza, Simone; Tekampe, Esther; Falkenburger, Björn; et al. Journal of Parkinson's Disease Vol. 16, no. 1, p. 170 - 176

New paper out: Fear of progression in Parkinson's disease: Role of age and occupational status.: D'Souza, Simone; Tekampe, Esther; Falkenburger, Björn; et al.
Journal of Parkinson's Disease Vol. 16, no. 1, p. 170 - 176 | Thanks for sharing #dzne #papers

01.03.2026 13:54 — 👍 2    🔁 0    💬 0    📌 0
Serum NfL, but not GFAP, differentiates primary lateral sclerosis from adrenomyeloneuropathy and hereditary spastic paraplegia type 4. Kessler, Christoph; Wilke, Carlo; Hengel, Holger; et al. Amyotrophic lateral sclerosis & frontotemporal degeneration Vol. 27, no. 1-2, p. 110 - 117

New paper out: Serum NfL, but not GFAP, differentiates primary lateral sclerosis from adrenomyeloneuropathy and hereditary spastic paraplegia type 4.: Kessler, Christoph; Wilke, Carlo; Hengel, Holger; et al.
Amyotrophic lateral sclerosis & frontotemporal… | Thanks for sharing #dzne #papers

01.03.2026 10:53 — 👍 1    🔁 0    💬 0    📌 0
Comparison of online radiologists and large language model chatbots in responding to common radiology-related questions in Chinese: a cross-sectional comparative analysis Ji, Jiang; Li, Chenguang; Fu, Yibin; et al. Quantitative imaging in medicine and surgery Vol. 16, no. 2, p. 129 - 129

New paper out: Comparison of online radiologists and large language model chatbots in responding to common radiology-related questions in Chinese: a cross-sectional comparative analysis: Ji, Jiang; Li, Chenguang; Fu, Yibin; et al.
Quantitative imaging in medicine… | Thanks for sharing #dzne #papers

28.02.2026 18:13 — 👍 2    🔁 0    💬 0    📌 0
The flexible synapse – How mossy fiber architecture adapts to changing needs Bruentgens, Felicitas; Schmitz, Dietmar; Orlando, Marta Progress in neurobiology Vol. 258, p. 102882 -

New paper out: The flexible synapse – How mossy fiber architecture adapts to changing needs: Bruentgens, Felicitas; Schmitz, Dietmar; Orlando, Marta
Progress in neurobiology Vol. 258, p. 102882 - | Thanks for sharing #dzne #papers

28.02.2026 13:53 — 👍 3    🔁 0    💬 0    📌 0
Automatically measured speech intelligibility models bulbar-specific disease severity and progression in Amyotrophic Lateral Sclerosis. Tröger, Johannes; Rouvalis, Andreas; Dörr, Felix; et al. Amyotrophic lateral sclerosis & frontotemporal degeneration Vol. 27, no. 1-2, p. 101 - 109

New paper out: Automatically measured speech intelligibility models bulbar-specific disease severity and progression in Amyotrophic Lateral Sclerosis.: Tröger, Johannes; Rouvalis, Andreas; Dörr, Felix; et al.
Amyotrophic lateral sclerosis & frontotemporal… | Thanks for sharing #dzne #papers

28.02.2026 10:54 — 👍 1    🔁 0    💬 0    📌 0
Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer's disease model. Zu, Juan; Li, Cong; Cui, Mochen; et al. Brain Vol. 149, no. 2, p. 668 - 679

New paper out: Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer's disease model.: Zu, Juan; Li, Cong; Cui, Mochen; et al.
Brain Vol. 149, no. 2, p. 668 - 679 | Thanks for sharing #dzne #papers

27.02.2026 18:13 — 👍 2    🔁 0    💬 0    📌 0
Associations between epilepsy-related polygenic risk and brain morphology in childhood. Ngo, Alexander; Liu, Lang; Larivière, Sara; et al. Brain Vol. 149, no. 2, p. 519 - 533

New paper out: Associations between epilepsy-related polygenic risk and brain morphology in childhood.: Ngo, Alexander; Liu, Lang; Larivière, Sara; et al.
Brain Vol. 149, no. 2, p. 519 - 533 | Thanks for sharing #dzne #papers

27.02.2026 13:54 — 👍 2    🔁 0    💬 0    📌 0
Preview
Alpha‐synuclein quantitative seed amplification assay predicts conversion to dementia INTRODUCTION The alpha-synuclein seed amplification assay (SAA) has shown excellent performance in the detection of Lewy body pathology in cerebrospinal fluid (CSF). Lewy body pathology is prognosti...

Alpha-synuclein quantitative seed amplification assay predicts conversion to dementia.
Stefan Bräuer et al.
Alzheimer’s & Dementia: the Journal of the @alzassociation.bsky.social (2026).
DOI: doi.org/10.1002/alz....

27.02.2026 11:36 — 👍 1    🔁 0    💬 0    📌 0
Preview
New Assay Helps to Identify Elevated Dementia Risk The approach relies on the detection of pathological alpha-synuclein proteins.

Researchers from #DZNE & partners have developed a method to quantitatively measure pathological #AlphaSynuclein in cerebrospinal fluid, which may facilitate the identification of individuals at elevated risk of #dementia.
👉 www.dzne.de/en/im-fokus/...

27.02.2026 11:36 — 👍 5    🔁 2    💬 1    📌 0
Unraveling the intersection of aging and Parkinson's disease: a collaborative roadmap for advancing research models. Schmidt, M. Y.; Cuervo, A. M.; Double, K. L.; et al. npj Parkinson's Disease Vol. 12, no. 1, p. 28

New paper out: Unraveling the intersection of aging and Parkinson's disease: a collaborative roadmap for advancing research models.: Schmidt, M. Y.; Cuervo, A. M.; Double, K. L.; et al.
npj Parkinson's Disease Vol. 12, no. 1, p. 28 | Thanks for sharing #dzne #papers

27.02.2026 10:54 — 👍 2    🔁 0    💬 0    📌 0
Modifiable Factors Associated with the Longitudinal Increase and Spatial Extent of Tau Pathology in Alzheimer Disease. Hoenig, Merle C; Dzialas, Verena; Doering, Elena; et al. Journal of nuclear medicine Vol. 67, no. 2, p. jnumed.125.270593 -

New paper out: Modifiable Factors Associated with the Longitudinal Increase and Spatial Extent of Tau Pathology in Alzheimer Disease.: Hoenig, Merle C; Dzialas, Verena; Doering, Elena; et al.
Journal of nuclear medicine Vol. 67, no. 2, p. jnumed.125.270593 - | Thanks for sharing #dzne #papers

23.02.2026 10:53 — 👍 2    🔁 0    💬 0    📌 0
Prevalence of Alzheimer's disease pathology in the community. Aarsland, Dag; Sunde, Anita Lenora; Tovar-Rios, Diego A; et al. Nature Vol. 650, no. 8100, p. 182 - 186

New paper out: Prevalence of Alzheimer's disease pathology in the community.: Aarsland, Dag; Sunde, Anita Lenora; Tovar-Rios, Diego A; et al.
Nature Vol. 650, no. 8100, p. 182 - 186 | Thanks for sharing #dzne #papers

22.02.2026 18:13 — 👍 2    🔁 0    💬 0    📌 0
Older adults with subjective memory complaints and brain amyloidosis show stable electroencephalographic rhythms, cortical structure, and cognitive performances over 2 years Lopez, Susanna; Hampel, Harald; Percio, Claudio Del; et al. Alzheimer's and dementia Vol. 21, no. S2, p. e106502

New paper out: Older adults with subjective memory complaints and brain amyloidosis show stable electroencephalographic rhythms, cortical structure, and cognitive performances over 2 years: Lopez, Susanna; Hampel, Harald; Percio, Claudio Del; et al.
Alzheimer's… | Thanks for sharing #dzne #papers

22.02.2026 13:54 — 👍 3    🔁 0    💬 0    📌 0
Effects of lifestyle intervention and supplementation with insoluble oat fiber on cognitive functions in patients with prediabetes: a secondary analysis of the Optimal Fiber Trial. Kabisch, Stefan; Montagna, Federico; Honsek, Caroline; et al. Frontiers in nutrition Vol. 12, p. 1699958

New paper out: Effects of lifestyle intervention and supplementation with insoluble oat fiber on cognitive functions in patients with prediabetes: a secondary analysis of the Optimal Fiber Trial.: Kabisch, Stefan; Montagna, Federico; Honsek, Caroline; et al.… | Thanks for sharing #dzne #papers

22.02.2026 10:54 — 👍 2    🔁 0    💬 0    📌 0
Explainable Intermodality Medical Information Transfer Using Siamese Autoencoders Arco, Juan E.; Jimenez-Mesa, Carmen; Ortiz, Andrés; et al. IEEE transactions on radiation and plasma medical sciences Vol. 10, no. 2, p. 192 - 209

New paper out: Explainable Intermodality Medical Information Transfer Using Siamese Autoencoders: Arco, Juan E.; Jimenez-Mesa, Carmen; Ortiz, Andrés; et al.
IEEE transactions on radiation and plasma medical sciences Vol. 10, no. 2, p. 192 - 209 | Thanks for sharing #dzne #papers

21.02.2026 18:13 — 👍 3    🔁 0    💬 0    📌 0
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain. Zhilina, Diana; Bolaños Castro, Lizbeth A; Eguiguren, Juan Sebastian; et al. Developmental dynamics Vol. 255, no. 2, p. 187 - 208

New paper out: Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain.: Zhilina, Diana; Bolaños Castro, Lizbeth A; Eguiguren, Juan Sebastian; et al.
Developmental dynamics Vol. 255, no. 2, p. 187 - 208 | Thanks for sharing #dzne #papers

21.02.2026 13:53 — 👍 2    🔁 0    💬 0    📌 0
Collaborative neurocardiology board meetings for decision-making in stroke care: a real-world experience. Mafael, V.; Buck, T.; Stengl, Helena; et al. Neurological research and practice Vol. 8, no. 1, p. 4

New paper out: Collaborative neurocardiology board meetings for decision-making in stroke care: a real-world experience.: Mafael, V.; Buck, T.; Stengl, Helena; et al.
Neurological research and practice Vol. 8, no. 1, p. 4 | Thanks for sharing #dzne #papers

21.02.2026 10:53 — 👍 2    🔁 0    💬 0    📌 0