Mirko Pegoraro PhD's Avatar

Mirko Pegoraro PhD

@3volution.bsky.social

Lecturer in Epigenetics at Liverpool John Moores university. Focus on understanding Evolution via Natural Selection at multiple levels. I am interested in Genetics, Epigenetics and Molecular Biology. 🐝πŸͺ°πŸ¦ŸπŸœπŸ¦ πŸ§¬πŸŒˆhe/him Web: https://shorturl.at/WF8o3

360 Followers  |  418 Following  |  282 Posts  |  Joined: 12.11.2024  |  1.9766

Latest posts by 3volution.bsky.social on Bluesky

Young Frankenstein (1974)

Young Frankenstein (1974)

Young Frankenstein (1974)
Directed by Mel Brooks

05.12.2025 11:40 β€” πŸ‘ 859    πŸ” 93    πŸ’¬ 9    πŸ“Œ 2
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β€˜The only idea around’: will Labour return to a customs union with the EU? The desperate search for economic growth is pushing the party to confront the issue that dare not speak its name

β€œWe want growth. We know this is the single best way of getting it…
We could then challenge Farage… to either continue with our economic recovery, or to halt it in its tracks and take us backwards.”

Finally. Weaken Farage by doing something that actually works.
www.theguardian.com/politics/202...

06.12.2025 09:33 β€” πŸ‘ 496    πŸ” 159    πŸ’¬ 39    πŸ“Œ 8

I just need a very very good #Alien movie πŸŽ₯ right now.
@perfectorganism.bsky.social

06.12.2025 10:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Former Farage classmate tells James O'Brien why he came forward
YouTube video by LBC Former Farage classmate tells James O'Brien why he came forward

Here's the whole interview.
youtu.be/DMlj-Tn2_BA?...

05.12.2025 19:56 β€” πŸ‘ 576    πŸ” 208    πŸ’¬ 30    πŸ“Œ 19

I am reading that some funding bodies are exploring LLMs as β€œthird reviewer” or β€œmeta-reviewer” on grant applications. Man, it is already hard to convince humans to fund my research and we share language & experiences, but how am I going to convince an LLM? We don’t even share 🧬 #Skyacademics

05.12.2025 08:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Question time fans rage defund the BBC after small boat migrants planted in audience.

Question time fans rage defund the BBC after small boat migrants planted in audience.

The Express is furious about this because the moment you show those who repeat anti-immigration rhetoric the real human stories their narrative collapses.

The β€œimmigrants” are people. Our friends, colleagues and family.

And it’s this nation of neighbours that is what makes Britain great.

04.12.2025 23:23 β€” πŸ‘ 2205    πŸ” 542    πŸ’¬ 91    πŸ“Œ 39

Academia has this way of making you feel utterly unsuccessful even when by any reasonable standard you are doing just fine.

04.12.2025 03:24 β€” πŸ‘ 419    πŸ” 47    πŸ’¬ 8    πŸ“Œ 20

A friend with a new baby asked guests to mask in order to hold her baby. A relative refused to mask & broke down in tears about her "restrictions"

As a reminder, babies <6 months have the 2nd highest hospitalization rate from Covid after adults 75+ & are too young to be vaxxed

02.12.2025 20:01 β€” πŸ‘ 1474    πŸ” 350    πŸ’¬ 97    πŸ“Œ 40
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On this day in 1984, #Dune as directed by #DavidLynch premiered in the US. It's one of my favourite films of all time.

03.12.2025 17:17 β€” πŸ‘ 2181    πŸ” 223    πŸ’¬ 243    πŸ“Œ 55

β€œhuman attention β€” the scarcest resource in science”

03.12.2025 17:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Seventh patient in HIV remission after stem cell transplant | News | ConnectSci

In a world awash with negative science/health news this is unashamedly great news. connectsci.au/news/news-pa...

03.12.2025 07:21 β€” πŸ‘ 5994    πŸ” 1140    πŸ’¬ 82    πŸ“Œ 68
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Brexit: the trillion pound β€˜mistake’ The recent NBER report suggests the Treasury’s 2016 analysis – slammed by Brexiters as a β€˜hoax’– actually understated the impact of Brexit

"Assuming no change in the rate of taxation, and all other things being equal, the exchequer will lose the thick end of Β£100bn in tax revenues this year.

Far from having to raise Β£26bn in extra taxes, Reeves could have chosen to halve the 20% rate of VAT with money to spare."

02.12.2025 23:06 β€” πŸ‘ 188    πŸ” 79    πŸ’¬ 8    πŸ“Œ 3
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Shrimps and water fleas in distress - Artificial light at night disrupts freshwater ecosystems | University of Helsinki A new study from the University of Helsinki reveals that artificial light at night significantly affects freshwater invertebrates and their ecosystems.

Congratulations to Yuhan for successful PhD defence: Shrimps and water fleas in distress - Artificial light at night disrupts freshwater ecosystems www.helsinki.fi/en/news/anim...

03.12.2025 07:07 β€” πŸ‘ 832    πŸ” 230    πŸ’¬ 11    πŸ“Œ 17
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Reeves speech did not mislead on challenges facing UK ahead of Budget, says OBR official Prof David Miles tells MPs the messaging given by the chancellor was

Oh.
www.bbc.co.uk/news/article...

02.12.2025 15:48 β€” πŸ‘ 1430    πŸ” 353    πŸ’¬ 135    πŸ“Œ 22
CRISPR-Cas systems are divided into two classes (class 1 and class 2) and six main types (types I to VI), differentiated by their protein architecture and mechanisms of action. (b) The response consists of three stages: (I) adaptation – the insertion of foreign genetic material into the bacterial cell, followed by its recognition and cleavage by proteins from the adaptation module (black box, PAM-protospacer adjacent motif) to generate spacers. (II) Biogenesis: Transcription of the CRISPR locus. The resulting pre-CRISPR RNA (pre-crRNA) is processed by the Cas9/RNase III complex, which recognizes repeated sequences. The process produces mature crRNAs that subsequently pair with trans-activating CRISPR RNA (tracrRNA) to form guide RNA (gRNA). (III) Interference: When the genetic material is put back into the cell, if it has the right protospacer and PAM sites, the Cas/gRNA complexes recognize it and cut it.

CRISPR-Cas systems are divided into two classes (class 1 and class 2) and six main types (types I to VI), differentiated by their protein architecture and mechanisms of action. (b) The response consists of three stages: (I) adaptation – the insertion of foreign genetic material into the bacterial cell, followed by its recognition and cleavage by proteins from the adaptation module (black box, PAM-protospacer adjacent motif) to generate spacers. (II) Biogenesis: Transcription of the CRISPR locus. The resulting pre-CRISPR RNA (pre-crRNA) is processed by the Cas9/RNase III complex, which recognizes repeated sequences. The process produces mature crRNAs that subsequently pair with trans-activating CRISPR RNA (tracrRNA) to form guide RNA (gRNA). (III) Interference: When the genetic material is put back into the cell, if it has the right protospacer and PAM sites, the Cas/gRNA complexes recognize it and cut it.

A comprehensive review of genomic-scale genetic engineering as a strategy to improve bacterial productivity. Published Open Access and fee-free in Microbiology using a Publish and Read agreement: doi.org/10.1099/mic.... #MicrobioJ #PublishAndRead

02.12.2025 10:01 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Brexit was exactly that. A petulant door-slamming. A rejection of cooperation, protection and opportunity for all of us because the wealthy rightwing elites didn’t want to play by shared rules. And knew they could exploit ignorance/prejudice to achieve that.

02.12.2025 09:02 β€” πŸ‘ 354    πŸ” 70    πŸ’¬ 18    πŸ“Œ 1

One of my abiding impressions of Brexit is the way it slammed doors of opportunity in the faces of young people several rungs below Boris Johnson’s countless children on the ladders of privilege & advantage.

02.12.2025 07:46 β€” πŸ‘ 1484    πŸ” 349    πŸ’¬ 72    πŸ“Œ 8
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ANALYSIS | ChatGPT may help you find information faster, but you learn less | CBC Radio Bob McDonald’s Blog: Recent studies show that using chatbots like ChatGPT may get us information faster than ever before, but we’re not gaining much knowledge by using it.

This is why this garbage is being pushed on us so hard. They want to kill intellectual curiosity and learning.

www.cbc.ca/radio/quirks...

01.12.2025 16:30 β€” πŸ‘ 1776    πŸ” 519    πŸ’¬ 4    πŸ“Œ 3
NOTICE TO FEDERAL
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NOTICE TO FEDERAL LAW ENFORCEMENT THIS IS A PRIVATE UNIVERSITY BUILDING. VOLUNTARY CONSENT TO ENTRY OR SEARCH IS NOT GRANTED A SIGNED JUDICIAL WARRANT IS REQUIRED FOR ACCESS

UNC Faculty--ICE actions in the Triangle have terrified many of our students and their families. I posted these signs on outside doors of my building and am re-posting as they are removed. JOIN ME! They match what administrators told us to they shouldn't complain

01.12.2025 00:14 β€” πŸ‘ 58    πŸ” 21    πŸ’¬ 3    πŸ“Œ 1
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Russian influence petition surges past 100,000 signatures A petition demanding a full inquiry into Russian influence in UK politics has passed 100,000 signatures

β€œA petition demanding a full inquiry into Russian influence in UK politics has surged past 100,000 signatures after being shared at remarkable speed across social media.”

30.11.2025 11:01 β€” πŸ‘ 521    πŸ” 168    πŸ’¬ 12    πŸ“Œ 9
Video thumbnail

On Friday...

28.11.2025 22:29 β€” πŸ‘ 548    πŸ” 135    πŸ’¬ 55    πŸ“Œ 17
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Yet emigration by Brits has basically been the same for at least 4 years, with the rising trend due to increasing emigration by non-EU citizens.

Quite possibly due to the anti-foreigner / hostile environment so relentlessly pushed by the likes of the Mail.

www.ons.gov.uk/peoplepopula...

28.11.2025 14:47 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Signore Delle Cime con Silenzio - Coro Alpini
YouTube video by franztodd Signore Delle Cime con Silenzio - Coro Alpini

Tonight I am really missing the Dolomites, β€œle mie montagne”. πŸ”οΈ
The song of the video is actually a prayer for a friend lost to the mountains.

youtube.com/watch?v=ugi_...

27.11.2025 21:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ˜‚ my reactions would exactly the same . πŸ˜‚πŸ˜‚πŸ˜‚

27.11.2025 19:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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OHIO researcher co-authors new study showing pterosaurs and birds evolved flight-ready brains in different ways A new study published in Current Biology, co-authored by Lawrence Witmer, now sheds light on how pterosaurs evolved the neurological structures required for powered flight.

OHIO researcher co-authors new study showing pterosaurs and birds evolved flight-ready brains in different ways

www.ohio.edu/news/2025/11...

27.11.2025 08:42 β€” πŸ‘ 35    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0
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Denmark sets up β€˜night watch’ to monitor Trump since Greenland row US president’s threat to seize territory prompts intelligence briefings reminiscent of Game of Thrones patrol The Danish government has set up a β€œnight watch” in the foreign ministry, not to keep out the wildlings and White Walkers like the Night’s Watch of Game of Thrones, but rather to monitor Donald Trump’s pronouncements and movements while Copenhagen sleeps. The night watch starts at 5pm each day and at 7am a report is produced and distributed around the Danish government and relevant departments about what was said and took place, the Politiken newspaper reported. Continue reading...

Denmark sets up β€˜night watch’ to monitor Trump since Greenland row

27.11.2025 13:23 β€” πŸ‘ 593    πŸ” 177    πŸ’¬ 14    πŸ“Œ 32
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Keep out: what flags mean to community NHS workers Frontline NHS staff are feeling an increasing sense of exclusion and intimidation from the surge of St George’s flags displayed on homes

Frontline NHS staff are feeling an increasing sense of exclusion and intimidation from the surge of St George’s flags displayed on homes.

27.11.2025 07:46 β€” πŸ‘ 171    πŸ” 65    πŸ’¬ 19    πŸ“Œ 7
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Farage's antisemitism was targeted, persistent and nasty.
Source: www.theguardian.com/politics/202...

26.11.2025 08:21 β€” πŸ‘ 289    πŸ” 136    πŸ’¬ 18    πŸ“Œ 12

'Our research has found that patchy implementation of family-friendly policies and unsympathetic managerial cultures push women to work as if nothing has changed. They are required to give birth to the β€œideal academic baby”: a child who never disrupts grant deadlines, seminars or student emails.'

27.11.2025 08:52 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0

Oh Zia Yusufski, you and your Reform lot are going to have to get cross with *a lot* of people. Here’s Private Eye taking the piss out of you too.

26.11.2025 21:35 β€” πŸ‘ 511    πŸ” 162    πŸ’¬ 16    πŸ“Œ 1

@3volution is following 19 prominent accounts