Mirko Pegoraro PhD

Mirko Pegoraro PhD

@3volution.bsky.social

Lecturer in Epigenetics at Liverpool John Moores university. Focus on understanding Evolution via Natural Selection at multiple levels. I am interested in Genetics, Epigenetics and Molecular Biology. 🐝🪰🦟🐜🦠🧬🌈he/him Web: https://shorturl.at/WF8o3

400 Followers 429 Following 308 Posts Joined Nov 2024
23 hours ago
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Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...

A microbiome gut-brain pathway influenced by intestinal metabolites, innate immune responses, vagal nerve signaling and hippocampal memory encoding, impacts the rate of cognitive decline. Many potential points of intervention are described.
#Science 🧪

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2 days ago
Greens win with 45% of the vote

💚 Green Party WINS Aigburth ward Liverpool City Council for the first time – overturning more than 100 years of legacy-party control.

Huge thanks to more than 100 volunteers for getting out this big Green vote and to everyone in Aigburth for choosing hope.

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6 days ago
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✨Crepidula fornicata (slipper snail) 🐚 A classic model for spiral cleavage! 🧬 Crepidula embryos reveal how early cell divisions shape body plans and establish left-right asymmetry in spiralian animals 📸 Image by Jake Leyhr #ModelMonday

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6 days ago
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

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6 days ago

What works for me is having anxiety/worries diaries, categorise a/w (e.g. actionable non-actionable), scheduling a weekly a/w meeting when I let myself run wild, having plans with specific goals and deadlines for actionable a/w. Try grounding techniques like the 5-1 based on the senses. Stay strong.

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1 week ago
Very large dark red mayfly with wings held up straight, and giant two-toned compound eyes, orange in the upper third and dark blue below. She's holding her 1st leg pair forward and up like antennae Top down view of the creature's head, giant eyes protruding out like a drum set Face of the creature, big blue/orange eyes peering at everything everywhere all at once Extremely close shot of the creature's compound eyes

Throwback to the time This Thing appeared 👀 (giant mayfly, from 2021)

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1 week ago
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Introducing the campest katydid of all time. 🦄💅🏽👸💞 Why would this animal (Arota festae) have evolved this way, other than to look utterly fabulous? We have unleashed some (slightly whacky) thoughts, now out in @esajournals.bsky.social. Photo credit: @zekerowe.bsky.social doi.org/10.1002/ecy.... 1/n

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6 days ago
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feeling a lot of positive energy from #Dros26, it is so needed in these times. especially after sharing more broadly about how arts and music intersect with science, i had great convos with lots of people about this. check out this incredible tattoo! bonus points if you know what molecule it is... 🪰

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1 week ago
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Reverend Jesse Jackson called on each of us to be heralds of change, to be messengers of hope; to step forward and say “Send me” wherever we have a chance to make an impact.

How fortunate we were that Jesse Jackson answered that call. What a great debt we owe to him.

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1 week ago
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AOC: He impulsively went in on Venezuela. He impulsively went in on Iran. It led to increased global instability and every time he’s done that, it has been consistent with a spike in what is happening with the Epstein files. I think that he feels existentially tied to it.

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1 week ago

Migration is part of what makes this country great.

We're not an island of strangers - we're an island of neighbours.

The Green Party will always support fair & managed migration.

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1 week ago
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FT comments section this morning - saying what everyone else is thinking, right?

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1 week ago
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Media must stop normalizing the far right Every uncritical mention of far-right rhetoric is an editorial decision with political consequences.

Media must stop normalizing the far right
Every uncritical mention of far-right rhetoric is an editorial decision with political consequences

www.politico.eu/article/medi...

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1 week ago
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Ohh that's RICH
@ohhthatsrich.bsky.social

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1 week ago
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Ohh that's RICH
@ohhthatsrich.bsky.social

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2 weeks ago
Pope Leo XIV !
@Pontifex
X.com
I am following with deep concern what is happening in the Middle East and in Iran during this tumultuous time. Stability and peace are not achieved through mutual threats, nor through the use of weapons, which sow destruction, suffering, and death, but only through reasonable, sincere, and responsible dialogue.
7:33 AM • 3/1/26 • 39K Views
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Pope Leo XIV & @Pontifex • 18m
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Faced with the possibility of a tragedy of immense proportions, I make a heartfelt appeal to all the parties involved to assume the moral responsibility of halting the spiral of violence before it becomes an unbridgeable chasm. May diplomacy regain its proper role, and may the well-being of peoples, who yearn for peaceful existence founded on justice, be upheld. And let us continue to pray for peace.
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2 weeks ago
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2 weeks ago

Social media created this nonsense idea that not exposing yourself to hatred is isolationist. Choosing to not spend your free time with bigots isn’t living in a bubble. I don’t need to know what’s going on at X. I won’t be smarter or more knowledgeable or empathic by being there. Neither will you.

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2 weeks ago
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Melissa Dalton-Bradford

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2 weeks ago
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'I didn't grow up wanting to be a politician, I'm a plumber'

The green Party's Hannah Spencer has won the Gorton and Denton, with Reform in second and Labour finished third

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2 weeks ago
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Tax billionaires out of existence.

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2 weeks ago
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This mind-bending relativity illusion has never been seen—until now.

Using ultrafast lasers and a 300-picosecond camera, researchers at the University of Vienna and Vienna University of Technology visualized the rotating Terrell-Penrose effect, an effect of special relativity.

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2 weeks ago
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Drop in overseas workers is ‘car crash’ for UK hospitals and care homes, say experts Care roles hit particularly hard by UK’s lurch to the right on migration, according to analysis of Home Office data Hospitals and care homes in the UK face “an impending car crash”, experts have warned, as research shows the number of overseas nurses and carers has collapsed. Analysis of Home Office quarterly datasets reveals the number of overseas nurses granted entry to the UK has fallen by 93% over three years. Just 1,777 overseas nurses were granted entry in 2025, compared with 26,100 in 2022. Continue reading...

Drop in overseas workers is ‘car crash’ for UK hospitals and care homes, say experts

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2 weeks ago
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Sturgill Simpson Turtles All the Way Down

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2 weeks ago

I have done it again.
I donated #blood 🩸 today. It was super easy and the #nhs nurses were helpful and supportive.
A great experience as usual. I feel much lighter knowing that I did something good today.

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2 weeks ago
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Zelenskyy: “I thank all the leaders who are in Ukraine and with Ukraine today, and who have supported Ukrainians throughout all these years of struggle. It is extremely important that we are all together today, speaking with one voice.”

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2 weeks ago
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Ancient DNA Reveals Europe’s Last Hunter-Gatherers Survived Thousands of Years Longer Than Expected Ancient DNA shows that hunter-gatherers in northwestern Europe endured for millennia, with women driving a gradual cultural shift toward farming.

The findings that come from an DNA studies fascinate me. The fact that DNA can even be extracted from ancient bones (and sometimes teeth) is amazing.

Ancient DNA Reveals Europe’s Last Hunter-Gatherers Survived Thousands of Years Longer Than Expected share.google/WJYszOE4b4PE...

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2 weeks ago

There should be emphasis on the virtue of education as an end in itself. In my view education should be a right freely available up to degree level purely because of the net social benefit of an educated citizenry. Populism is driven above all by the poorly educated.

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3 weeks ago
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‘Don’t go to the US – not with Trump in charge’: the UK tourist with a valid visa detained by ICE for six weeks Karen Newton was in America on the trip of a lifetime when she was shackled, transported and held for weeks on end. With tourism to the US under increasing strain, she says, ‘If it can happen to me, i...

'She has a message for other tourists considering a trip to America: “Don’t go – not with Trump in charge. It’s totally out of control over there. There’s no accountability. They don’t seem to need a reason for detaining you.”'
#ICE
www.theguardian.com/us-news/2026...

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3 weeks ago
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Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC - Nature In a phase 1 trial, personalized mRNA vaccines tailored to individual tumour mutations in triple-negative breast cancer induced robust, long-lasting T cell responses and improved prognosis.

More hope from mRNA vaccines. In this instance, individualized vaccines were given to women with triple negative breast cancer following surgery and adjuvant therapy. The results are quite remarkable. Despite cancer finding a ‘T cell-evading’ work-around in some patients.
#Science 🧪

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