GregoryP

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Intrathecal onasemnogene abeparvovec in treatment-naive patients with spinal muscular atrophy: a phase 3, randomized controlled trial - Nature Medicine The phase 3 STEER trial showed that a single intrathecal dose of onasemnogene abeparvovec significantly improved motor function in children and adolescents with spinal muscular atrophy versus sham, with a similar and acceptable safety profile.

Research in Nature Medicine finds that a single-dose gene replacement therapy improves movement ability in children over 2 years old and teens with spinal muscular atrophy. The results could support an alternative to lifelong, repeat-dose treatments for people living with spinal atrophy. #medsky 🧪

An Empire of Nature: African Parks and Rwanda’s Nyungwe Forest NYUNGWE NATIONAL PARK, Rwanda — It’s a cool morning in the montane rainforest of western Rwanda’s Nyungwe National Park. Sunbeams stream down from the canopy, glowing in the mist. Birdsong pierces…

African Parks took over management of Rwanda’s vast Nyungwe rainforest in 2020 under a 20-year deal.

Now operating 24 protected areas in 13 countries, the NGO is a major force in Africa’s public-private conservation model. Mongabay visited Nyungwe to see it firsthand.

A rare bright spot for whales: Decades of conservation pay off for endangered population in Canada Populations of northern bottlenose whales (Hyperoodon ampullatus), playful animals that resemble large dolphins, stretch across the Atlantic Ocean, with each group of whales living year-round in a…

Northern bottlenose whales have struggled to rebound even decades after whaling bans.

But a population off Canada’s east coast is finally recovering after the Gully submarine canyon became a Marine Protected Area in 2004 — a rare marine conservation success.

How dropping ads set us free to focus on impact Founder’s Briefs: An occasional series where Mongabay founder Rhett Ayers Butler shares analysis, perspectives and story summaries. Alejandro Prescott-Cornejo, Mongabay’s senior marketing associate,…

[FOUNDER'S BRIEF - @rhettayersbutler.bsky.social]

In 2012, Mongabay shifted from ads to a nonprofit model. Mongabay Indonesia showed that journalism could drive real transparency and impact. Leaving ads behind let us focus on public-interest reporting, collaboration and global reach — not clicks.

Warmer climate triggers pest infestations in Bangladesh, India tea estates The extended summers, delayed monsoons and shorter winters — collectively featuring a warmer climate — are triggering pest infestations across tea estates in Bangladesh and India. Entomologists have…

A warming climate is driving pest outbreaks across tea estates in Bangladesh and India. With pesticides failing, growers face major production and income losses.

Experts say the solution lies in integrated pest management and rebuilding soil health.

YouTube video by Netflix Is A Joke Mr. Pillow With Jon Hamm | Sarah Cooper: Everything's Fine | Netflix Is A Joke

youtu.be/PliKYqvFlpY?...

Generation of EM under the continents.

Continental rifting erodes mantle roots, transporting enriched material into oceans and driving oceanic volcanism. A study in Nature Geoscience shows that continental break-up reorganizes shallow mantle dynamics, affecting the geosphere and carbon cycle.
go.nature.com/3XjAk4G ⚒️ 🧪

📣A new FAO blog highlights how WorldFish's IkanAdapt project is supporting climate resilience in Timor-Leste’s aquatic food systems.

https://www.fao.org/fishery/en/news/41515

SIPRI Top 100 arms producers see combined revenues surge as states rush to modernize and expand arsenals (Stockholm, 1 December 2025) Revenues from sales of arms and military services by the 100 largest arms-producing companies rose by 5.9 per cent in 2024, reaching a record $679 billion, according to ne...

www.sipri.org/media/press-...

Oil Market Report - November 2025 – Analysis - IEA Oil Market Report - November 2025 - Analysis and key findings. A report by the International Energy Agency.

www.iea.org/reports/oil-...

but new governmental initiatives and other consumer protection laws are the primary tools used to combat scam activity.

The Age Discrimination Act 2004 (Cth) is an Australian law designed to protect people from unfair treatment based on age in areas like employment, education, and the provision of goods and services. It does not directly provide a mechanism to prosecute scammers,

www.iiss.org/online-analy...

Joan Miró “The Nightingale’s Song and Morning Rain” (1940) • To make this painting, the artist painted fanciful black lines and vibrant flat shapes that change color whenever they cross over a line. Red switches to black…black switches to blue…blue switches to red. This picture pulses, like a universe with music in its soul. • “I felt a deep desire to flee,” said Miró. “I shut myself within myself. Music and the stars began to play a major role in suggesting my paintings."

#ArtHistory 🗃️ 🐡 #painting

Happy Sunday, Blueskiis

Miró painted the moon and the stars as a coping mechanism to escape from the cruelty and devastation of World War II into the comfort of a fantasy world.

Joan Miró “Nightingale’s Song & Morning Rain” (1940) • More in ALT

YouTube video by Babyface Stop Buying Brooders! 🐔 Genius IBC Tote Hack #ytshorts #shorts #creativity

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This is figure 1, which shows the anatomy of the appendix.

Acute appendicitis is a leading cause of abdominal pain and emergency surgery in children and adults worldwide. A Primer in Nature Reviews Disease Primers reviews its epidemiology, diagnosis, management, and future research directions. go.nature.com/4ru8Vuq #medsky 🧪

A crust of translucent light green chalcosiderite crystals with a rounded shape on rusty coloured quartz. From Phoenix Mine, Cornwall, England, UK. Specimen on display in the Natural History Museum, London.

337 of #365Minerals 🧪⚒️

Chalcosiderite:
- A rare phosphate mineral
- Forms in the oxidised zone of some hydrothermal deposits
- Its name comes from the Greek words "χαλκος/chalkos" (copper) and "σίδηρος/sideros" (iron) because of its composition #minerals

A forced labor cartoon This is a political cartoon by Portuguese artist Vasco Gargalo that highlights the issue of forced labor and modern slavery in global supply chains, particularly in the fast fashion industry. Shows shows an oversized sewing machine shaped with the world map clearly visible on its body. A woman in an elegant red gown stands confidently in front of the machine, the end of the train of her gown under the needle of the sewing machine. Behind the needle, an exhausted human being in gray kneels inside the machine’s base, hunched over and sewing—representing modern slavery hidden within global supply chains.

December 2 is the International Day for the Abolition of Slavery.

An estimated 50,000,000 people are enslaved today in various forms of modern-day slavery.

www.un.org/en/observanc...

#AbolishSlavery #HumanRights #16DaysOfActivism

Submarine Kapitänleutnant Heinz Eck was sentenced to death for his role in the murder of survivors from the Greek steamer Peleus, though he claimed he was not acting under the order but on his own initiative.

Korvettenkapitän Karl-Heinz Moehle, who transmitted the order, was convicted and sentenced to five years in prison.

that had been sunk. Ambiguous wording: The order was ambiguously worded, and the interpretation was a key point in the trials of German officers after the war. Post-war trials:
Grand Admiral Karl Doenitz, who issued the order, denied its interpretation at the Nuremberg trials.

A 1942 German naval order could have been interpreted as directing U-boat crews to murder survivors.
The Laconia Order: In 1942, a German order was issued that could have been interpreted as a directive to kill the survivors of Allied ships

However, a related incident, the "Laconia Order," led to the deaths of shipwrecked sailors.

entire U-Boat crew held responsible and trialed for Murder at Sea

questioned and killed in the water

sunk. He also offered the Germans the provisions that could be found on board, but the U-boat left after firing one G7a torpedo as coup de grâce at 23.04 hours, which struck the drifting Ioanna on starboard side and caused her to sink after 10 minutes. The survivors later landed at Vigo.

At 22.25 hours, the U-boat had fired a G7a torpedo that was a circle runner. The crew immediately abandoned ship and were questioned by the Germans. The master told them that he was a former Greek submarine commander and he left the papers behind because it was clear for him that his ship would be

At 23.04 hours on 1 June 1940 the unescorted Ioanna (Master Vasilis Laskos), a straggler from convoy HG-32F since the night of 29/30 May, was stopped by three shots across her bow by U-37 about 120 miles west of Cape Finisterre.

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