Seth Masters

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...

So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience

@nhmrc.bsky.social

06.10.2025 21:27 — 👍 16    🔁 12    💬 2    📌 4

Amazing work by first author @shouyafeng.bsky.social with the support of @hudsonresearch.bsky.social and many others!!!

11.02.2025 09:57 — 👍 3    🔁 0    💬 0    📌 0

We tested this library of NLRP3 variants in response to stimulation, at low temperature (some patients with CAPS have temperature sensitive flares), and in response to a NLRP3 inhibitor, all of which yielded interesting results. If you have another idea, we are happy to share the library with you!

11.02.2025 09:57 — 👍 4    🔁 0    💬 1    📌 0

Infevers

Data available through
infevers.umai-montpellier.fr
and
www.geniadb.net/app/gene/inf...
any variants we did not test yet please let me know!

11.02.2025 09:57 — 👍 0    🔁 0    💬 1    📌 0

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants Nature Immunology - Gain-of-function variants in the gene encoding NLRP3 lead to constitutive inflammasome activation and excessive IL-1β production. In this resource, authors perform...

A large dataset we hope is helpful for patients who may have CAPS, an #autoinflammatory condition associated with genetic variants in NLRP3. Lots of "variants of uncertain significance" now have a specific readout from our in vitro assay which can help with clinical diagnosis.
rdcu.be/d9iRG

11.02.2025 09:57 — 👍 50    🔁 19    💬 6    📌 1

My apologies, it looks like this meeting is not being broadcast. Depending on what you are interested to hear about, there could be some recordings or other resources I can point you towards.

07.02.2025 02:50 — 👍 1    🔁 0    💬 0    📌 0

A really important consideration in the study of #autoinflammatory and other primary immune diseases. Extremely interesting findings @bogunoviclab.bsky.social !

01.01.2025 21:41 — 👍 3    🔁 0    💬 0    📌 0

3rd Autoinflammatory Disease Symposium & Education Summit on Paediatric Rheumatology Following previous meetings in 2017 (Garvan Institute) and 2022 (WEHI), the 3rd Autoinflammatory Disease Symposium will be combined with an Education Summit on Paediatric Rheumatology, in partnership ...

The 3rd Australian #autoinflammatory Disease Symposium will be combined with an Education Summit on Paediatric Rheumatology, in partnership with Zoe’s Angels:

21-22 Feb 2025 in Brisbane!

imb.uq.edu.au/event/20941/...

14.12.2024 23:15 — 👍 10    🔁 2    💬 1    📌 0

Here is a feed if you are interested to see things relating to Autoinflammation and Autoinflammatory Disease

bsky.app/profile/did:...

14.12.2024 23:06 — 👍 4    🔁 1    💬 0    📌 0

https://issaid.org/issaid2025/

The premier international conference for #autoinflammatory disease research only happens every 2 years. Don't miss this next instalment in Paris April 8th to 10th 2025!

Abstract submissions closing soon.

issaid.org/issaid2025/

14.12.2024 23:03 — 👍 13    🔁 4    💬 2    📌 0

InflammaZoom Join me online at the next InflammaZoom webinar!

Looks like a great inflammazoom coming up Dec 16 with @inflammasomelab.bsky.social and Si Ming Man! These talks are great for everyone interested in autoinflammation.

Register here to access the live session as well as on-demand talks from past sessions: events.abcam.com/AnYVL?rt=Qlp...

14.12.2024 22:48 — 👍 13    🔁 3    💬 0    📌 1

A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases.

Please let me know if you’d like to be added.

go.bsky.app/5M6obrp

07.12.2024 02:10 — 👍 35    🔁 15    💬 16    📌 1