Ermal Ismalaj

🚨 𝗝𝗼𝗯 𝗼𝗳𝗳𝗲𝗿: 𝗣𝗵𝗗 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻🚨

📅 Deadline: 07th Nov 2025
🔬 Envisaged start date: Jan 2026
📍 Location: San Sebastian (Spain)

👉To apply: https://www.cicbiomagune.es/job-offer-detail?id=43030

#JobOfferCICbiomaGUNE

I will definitely !!

We have an open PhD position in organic chemistry and radiochemistry. if you want to apply your medchem skills to PET imaging ligand design, join us in the beautiful San Sebastian.
#chemsky #radiochemistry

Details and how to apply below
www.cicbiomagune.es/job-offer-de...

Appreciated sharing!!

The peer-review crisis: how to fix an overloaded system Journals and funders are trying to boost the speed and effectiveness of review processes that are under strain.

The peer-review crisis: how to fix an overloaded system
www.nature.com/articles/d41...

Alguien tenía que arriesgarse a quedar mal haciendo esta lista 😊
Como estoy seguro de que me olvido de amig@s y personas que deberían estar aquí, hacédmelo saber en los replies para añadiros. #ChemSky

go.bsky.app/5WU81dp

Me puedes añadir a la lista por favor? Gracias de antelacion

🧠 PET Imaging agents for neurodegenerative diseases
❤️ Novel cardiac imaging PET tracers
⚛️ [18F]SF6 activation strategies in radiochemistry
Interested in designing novel imaging agents? Get in touch with us to explore how we can support your application and other possibilities🌟

📢 We are looking for motivated postdocs with a strong organic chemistry/radiochemistry background willing to apply for prestigious (inter)national grants, starting from the upcoming #JuandelaCierva, and join the Molecular Imaging Unit at #cicbiomagune by early 2026. #chemsky
Research areas:

Sorry OrgChem has reached the 150 limit, but we just started the sequel OrgChem2 and included you!
go.bsky.app/GwH8tnF

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1 biorxiv.org/cgi/content/short/2024.12.05.627058v1

Our OrgChem Starter Pack is growing with already 122 entries, but we will start a volume 2 if we go over the 150 limit!
go.bsky.app/NSEFPFJ

Add me up as well, please! Thanks

2024 Molecules of the Year Poll Serving the chemical, life science, and laboratory worlds

What do you think was the standout molecule of 2024?

Once again, C&EN editors dug into the depths of the magazine to find the most curious, wondrous, and just plain neat molecules of the past year.

Which one strikes your fancy? cen.acs.org/sections/mot... #chemsky #bluesci #chemistry🧪

Novel Far-Red Fluorescent 1,4-Dihydropyridines for L-Type Calcium Channel Imaging Upregulation of L-type calcium channels (LTCCs) is implicated in a range of cardiovascular and neurological disorders. Therefore, the development of toolboxes that unlock fast imaging protocols in live cells is coveted. Herein, we report a library of first-in-class far-red small-molecule-based fluorescent ligands (FluoDiPines), able to target LTCCs. All fluorescent ligands were evaluated in whole-cell patch-clamp and live-cell Ca2+ imaging whereby FluoDiPine 6 was found to be the best candidate for live-cell fluorescence imaging. Low concentration of FluoDiPine 6 (50 nM) and a quick labeling protocol (5 min) are successfully applied to fixed and live cells to image LTCCs with good specificity.

Check out our latest fluorescent ligands targeting voltage-gated calcium channels pubs.acs.org/doi/abs/10.1...
Happy to share these toolkits with anyone interested from #ionchannel community #chemsky. A huge thanks to all collaborators

How long are medicines good for? Stability data is necessary but tedious work

One thing @chemjobber.bsky.social appreciates about the commercial chemical manufacturing world is that it uses the standard ‘retest date’, rather than the food-related term ‘expiration date’.
www.chemistryworld.com/opinion/how-...