Biofabrication Würzburg

Are you a student just starting in the field of #bioprinting or #biofabrication? this review is for you!
Check our new review about the current status of bioprinting organs from the perspective of phd students, out now on Advanced Healthcare Materials
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Bioprinting organs: science or fiction?
Finally online a broad and comprehensive snap shot of where we're at but also a glimpse and bet into the future with the particular perspective of phd students working on it every day.

Check our latest publication about fabricating fibrillar bundle additives for muscle #bioprinting
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Here we are in Dresden for the annual #DGBM25 Conference!
Come find us around at the poster session
our team is showing their latest resuls on #biofabrication, #bioprinting and #bone cements
tomorrow at 11 nathaly chicaiza will have her talk on #vasculature bioprinting

Want to know more about #antibiotic-loaded mineral #bone #cements?

check out our new publication in Acta Biomaterialia:
"Interaction mechanisms between antibiotics and calcium phosphate cements as pharmacologically active bone graft substitutes"
www.sciencedirect.com/science/arti...

Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes - Journal of Orthopaedic Surgery and Research Background Ready-to-use non-aqueous cement pastes consist of an organic, water-miscible liquid phase in which cement powder is dispersed. While the modification of classical aqueous powder/liquid cement pastes with antibiotics has been extensively investigated, only a few studies previously published aimed at drug modification of premixed cement pastes. Methods A simple method for modifying such ready-to-use pastes with the model antibiotic vancomycin is described. It was demonstrated that mixing the cement paste and vancomycin solution multiple times using an adapter between two syringes resulted in macroscopically homogeneous pastes. The antibiotic-loaded cements were thoroughly characterized with regard to their physicochemical properties and their drug release profile. Results Drug modification with vancomycin had no adverse effects on cement properties in terms of mechanical performance, phase composition, porosity and pore size distribution. Drug release from ready-to-use pastes exhibited a lower initial burst release of 14.5% compared to 47.9% for aqueous powder/liquid cement pastes after 24 h. At later time points, the initial exponential release kinetics slowed down due to both a decreased concentration gradient and structural changes of the cement matrix during setting. This resulted in sustained release of the antibiotic for more than 30 days. The released vancomycin maintained high antimicrobial activity against S. aureus with inhibition zones of 5.4–6.8 mm in an agar diffusion test. Conclusion The results demonstrated that modification of ready-to-use cement pastes with vancomycin is a potential candidate for clinical application, as it preserves both the material’s properties and the antibiotic’s activity.

New publication from our Bone Cements group:
Clinically applicable antibiotic modification of ready-to-use calcium phosphate cement pastes
link.springer.com/article/10.1...

New publication in collaboration with Dr. Torsten Blunk's lab:
congrats @camillamussoni.bsky.social and colleagues
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Later this week we will be in Dresden for the #DGBM German Society for #Biomaterials Annual Conference.
Here all our contributions you can look forward to

Annual Betriebsausflug on the way in Marktbreit,
the fall landscape nicely framed our excursion!

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization A biomimetic vascular graft combining biofunctionalized PVA-MA hydrogels with a MEW scaffold is developed for small-diameter applications. Gel-MA and Hep-MA incorporation enhances endothelialization ...

New publication!
A novel biomimetic approach by combining PVA-MA-based hydrogels with #MEW scaffolds, creating a customizable #vasculargraft where the #hydrogels offer potential as ECM for cell attachment while the MEW scaffolds provide reinforcement
advanced.onlinelibrary.wiley.com/doi/10.1002/...

here the summary of our experience in Warsaw at #ISBF #Biofabrication2025 with the CRC TRR225 Biofabrication, so much fun!

#biofabrication #biofabrication #isbf #awards #biofabrication2025 #sciencecommunication #iop | Biofabrication 2025 🖼️ IOP Best Poster Awards 2025 🖼️ We are pleased to announce the winners of the IOP Best Poster Awards presented at the International Society for Biofabrication 2025 Conference. These awards honor pos...

love that ISBF notice
www.linkedin.com/posts/biofab...

Back from #ISBFWarsaw2025, what a fantastic time I had this week
I couldn't imagine a better way to conclude my phd journey in the #Biofabrication family than this.
I am grateful to the ISBF for granting me the IOP Best Poster Award at #Biofabrication2025.

We had an absolutely amazing time at #ISBFWarsaw2025!
The #Biofabrication2025 conference always feels like a family reunion, it was good to catch up with friends and learn about the latest results and share what we've been up to!
It was truly inspiring to see the community come together once more.

another busy day over in Warsaw for #Biofabrication2025.
here the summary of our fantastic day of talks 📊 and posters 📃
#ISBFWarsaw2025

a new day of talks and poster, we already had 2 rapid fire talks early this morning, check out prof. Groll and prof. Jüngst's talks and Nathaly Chicaiza's poster today!
#Biofabrication2025 #ISBFWarsaw2025

we wrap a very productive conference day2 with lots of presentations and insights!
Congratulations to president elect prof. Groll, we wish you a successful term!
Time to enjoy the young scientist🧑🏾‍🔬 night ✨ full of partying and networking 💃🏽🕺🏼
#Biofabrication2025 #ISBFWarsaw2025

very busy day today for the FMZ, check our talks and posters:
#Biofabrication2025 #ISBFWarsaw2025

Only 3 days left and we'll also be in Warsaw🇵🇱 for #Biofabrication2025!

Here all our contributions from @uni-wuerzburg.de, presenting many of our #meltelectrowriting and #bioprinting projects.

🌟Can't wait to see you all there!🌟

FRONT COVER is live!

💼 We are hiring!
We are looking for a postdoctoral researcher with a solid background in polymer synthesis for biomedical applications.
The job is within the EU project Daedalus, for regeneration of the colorectal mucosa using in situ 4D bioprinting.

⬇️ APPLY NOW ⬇️
karriere.ukw.de/en/p/intrane...

Back in Germany after an amazing summer in Cali, a huge thanks to all members of the @heilshornlab.bsky.social for welcoming me and sharing their work and time with me! You guys made this stay special. Very grateful to prof Sarah for hosting me.
Very happy with all I achieved!

This study explores the fabrication of nanofibrillar scaffolds through the melt electrofibrillation of polycaprolactone to guide myogenic differentiation. The scaffolds provide nanofibrillar cues that promote cell organization and integration, mimicking key features of the ECM

💪🏼New paper! 💪🏼

Bioassembly of Myoblast Spheroids in Electrofibrillated Scaffolds for 3D #Muscle #Tissue #Biofabrication

onlinelibrary.wiley.com/doi/10.1002/...

High‐Throughput Mechanical Characterization of Single Microgel Particles by Fluidic Force Microscopy The combination of atomic force microscopy and nanofluidics (FluidFM) allows for a new approach for the mechanical characterization of particulate soft matter in the micrometer regime by inverted nan....

New publication!

A new approach to nanoindentation for microgels is presented where the roles of the sample and the indenter are reversed.
onlinelibrary.wiley.com/doi/10.1002/...

Zan Lamberger discusses the cellular mechanisms that govern interactions with fibrous microenvironments, key design parameters for fiber-based substrates and strategies for translating these principles into 3d fiber-reinforced constructs for creating biomimetic environments.

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment...

New Review Out!
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
#Biofabrication #Biomaterials
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Efficient encapsulation of CRISPR-Cas9 RNP in bioreducible nanogels and release in a cytosol-mimicking environment - Discover Nano CRISPR/Cas9-mediated programmable gene editing has disrupted the biotechnology industry since it was first described in 2012. Safe in vivo delivery is a key bottleneck for its therapeutic use. Viral v...

Efficient encapsulation of CRISPR-Cas9 RNP in bioreducible nanogels and release in a cytosol-mimicking environment
link.springer.com/article/10.1...

we are back from a very successful retreat!
great opportunity for networking, team building and think of the future.
the main topic we addressed were the rise of AI, data management, career options and a refresher on FMZ values at the chair. but also lots of fun and good food!

Team Thullinger got 2nd place at ChemCup2025!
so much fun despite the heat
let's go!