Excellent, comprehensive rundown of the state of bio lab automation by @owlposting1.bsky.social
In retrospect, it's an important topic that has had almost zero discussion over the years!
A fun surprise to see some decade-old(!) work show up in there too.
www.owlposting.com/p/heuristics...
The truth behind the 2026 J.P. Morgan Healthcare Conference
www.owlposting.com/p/the-truth-...
happy JPM to all those who celebrate! wrote up some notes and observations for the week. lots to look forward to
essay tomorrow morning over cancer, and the role machine intelligence will play in how we treat the disease
subscribe to owlposting.com to read the first article that i literally could not have produced had i not been around oncology researchers for the last 5 months
I really like this essay from @owlposting1.bsky.social : www.owlposting.com/p/ask-not-wh...
Joining Noetik
www.owlposting.com/p/joining-no...
after a restful month of funemployment, i joined a biotech startup called Noetik last week. this essay explains my current beliefs about the ML-bio field, why I joined Noetik, and what they are working on
2.8k words, 14 minutes reading time
fair points all around! will add this to a follow up commentary post about it
I read this cool piece by @owlposting1.bsky.social on endometriosis on @scientificdiscovery.dev's recommendation
www.owlposting.com/p/endometrio...
One point is that endometriosis is very common, 10% of women according to the WHO. Which makes the paltry research (funding) even more galling.
Endometriosis is an incredibly interesting disease
5k words, 23 minutes reading time
covering one of the strangest conditions ive ever heard about
link: www.owlposting.com/p/endometrio...
doing some thinking
What could Alphafold 4 look like? (Sergey Ovchinnikov, Ep #3)
Substack: www.owlposting.com/p/what-could...
Youtube: youtu.be/6_RFXNxy62c
Spotify: open.spotify.com/episode/0wPs...
Apple Podcasts: podcasts.apple.com/us/podcast/w...
Transcript: www.owlposting.com/p/what-could...
tomorrow!
Endorse. @owlposting1.bsky.social is a great addition to the biotech blogosphere.
This was such an interesting post! It's awesome how much bio and biotech blogging are happening now and this is one of my newest favourites.
new posters of @rowan, a molecular simulation company
link to shop: owlpostingshop.com/products/rowan
www.owlposting.com/p/roundup-1-...
some announcements, some links, and some job listings!
also, ive been making biology-themed art lately! link is in the top section of the above link, underneath ‘Artwork’
Is there such a thing as an impossible protein?
www.owlposting.com/p/is-there-s...
tldr: no, but yes, but no, but yes
tiny article today
1.3k words, 7 minute reading time
Better antibodies by engineering targets, not engineering antibodies (Nabla Bio)
www.owlposting.com/p/better-ant...
another startup coverage article! the first one ive written over an antibody startup
the interesting part about them? how they think about targets, not antibodies
spent the holiday making biology-themed posters
here are my favorites
fwiw, this is the longest article ive ever written and 2 months in the making
ive wanted to write about cryo-EM for suuuch a long time, but it kept getting pushed aside because of how much material there was to go through. so happy i finally finished it up
now i can rest
A primer on ML in cryo-electron microscopy (cryo-EM)
www.owlposting.com/p/a-primer-o...
confused about cryo-EM???
i explain why people do it, how it works and some ML problems in the area via explanations of 3 ellen zhong papers
7.9k words, 36 minutes reading time. ToC in thread❄️
while the o1 verdict was wrong on all three papers, its response was sufficiently intelligent enough that it was still an interesting exercise to figure out how exactly it was wrong, especially for the third paper
read the article for more details!
Can o1-preview find major mistakes amongst 59 NeurIPS '24 MLSB papers?
www.owlposting.com/p/can-o1-pre...
i feed (nearly) an entire workshops worth of papers through o1, and ask if there are any major scientific errors amongst them. it says there are 3.
afaict, none of the 3 have errors
paid post bc i am gathering funds for the next podcast
ty for reading! next post will be (finally) another huge technical primer piece
A retrospective on filming a science podcast
www.owlposting.com/p/a-retrospe...
its been about a week since i released my first podcast. i want to document the whole process and why i did it and how i did it and if ill do it again (i will)
2.5k words, 12 minutes reading time
this is so kind!!! thank you for listening
Can AI improve the current state of molecular simulation?
www.owlposting.com/p/can-ai-imp...
in my first podcast, I spend 2 hours interviewing Corin Wagen and Ari Wagen, two brothers who are building the next generation of molecular simulation for drug discovery and material science
i have discovered long term transcriptomic alterations in the scRNA-seq data of neurons of mice who have been exposed to five hour long podcasts. i dont know what this means but the paper is coming out in Nature tomorrow (auto accept). i will not be sharing the data
the following people:
Adam Green (at markov bio)
Liam Bai (independent work)
John Yang (at Reticular, a YC startup)
Elana Simon (Stanford)
weird case of synchronicity where 4 independent people have published mechanistic interpretability work on biology models all in the same month, where there was basically nothing prior to them
