Last day at #InSiGHT2026 with a session for Early-onset colorectal cancers that I had the pleasure to co-chair. Thank you for thoughtful discussions with the speakers & audience !
Lastly, thank you for the support from @nanoporetech.com on the project and more updates to come!
Day 2 at #InSiGHT2026 with thought provoking talks on the molecular features of Lynch Syndrome. Thankful for the opportunity to give a talk in collaboration with Illumina Simeen and Shunhua Han on the newly released TruPath Genome.
Looking forward to the next 2 days of talks!
Wonderful opportunity to work on cancer genome reconstruction with long reads!
11.12.2025 03:53 — 👍 2 🔁 0 💬 0 📌 0
Looking for a postdoc in computational biology? We are looking for a postdoc candidate apply for the fellowship 'Juan de la Cierva' for a project on long-read transcriptomics, multiomics, spatial transcriptomics, single-cell long-reads. Deadline is approaching!! (December 10th)
08.12.2025 12:06 — 👍 4 🔁 7 💬 0 📌 0
The structure of the bacterial genotoxin colibactin bound to DNA shows how it might contribute to cancer risk @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Excited to see this thought provoking piece of work now published. So much more to learn about mutagenesis in healthy tissue.
09.10.2025 23:51 — 👍 3 🔁 2 💬 0 📌 0
Black and white portrait of John Gurdon, 1971
John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews
Rest in peace Jane Goodall, a true giant among scientists. Your breakthroughs into the secret lives of chimpanzees viewed through an anthropomorphic lens – without yet knowing that science had forbidden it – changed science forever, and with it how we see ourselves.
01.10.2025 20:44 — 👍 58 🔁 8 💬 0 📌 0Elegant work to unveil the etiology behind the ubiquitous SBS5 mutational signature. Glad to be in the audience to see this work presented and I have already put it on my reading list.
03.09.2025 12:32 — 👍 5 🔁 0 💬 0 📌 0
We are all somatic mutation mosaics.
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...
If you don’t have time to take a walk, then you don’t have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.
30.06.2025 08:19 — 👍 82 🔁 14 💬 5 📌 4
Excited for the talks on the amazing biology of ecDNA! Interested in ecDNA in esophageal cancers and long read sequencing? Always happy to chat!
#CancerGrandChallenges #CGCecDNA
Attending BRCA Symposium 2025 and enjoying a master class from Ralph Scilly on HRD. I will also start calling SBS3 bland from now on.
07.05.2025 19:28 — 👍 3 🔁 0 💬 0 📌 0
Interesting work from Khi Pin Chua, PhD on precise characterization of complex repeat regions in cancer genomes at #AACR25. Catch him at poster 2 in section 46 (#6288) until 5 PM! #PacBio
29.04.2025 19:29 — 👍 4 🔁 3 💬 0 📌 0
“If left unchallenged, a rising wave of white nationalism in many parts of the globe could threaten the progress that has been made in science — and broader society — towards a more equitable world,” writes Genevieve Wojcik in a Comment article for Nature. 🧬 🧪
26.04.2025 22:37 — 👍 127 🔁 81 💬 8 📌 3We should catch up! Was looking around to see if you were here!
26.04.2025 19:04 — 👍 1 🔁 0 💬 0 📌 0
Maybe I need to look at some head and neck cancer to study both DNA repair and ecDNAs. Come look for me at #AACR25 if you like to chat!
26.04.2025 16:16 — 👍 6 🔁 0 💬 0 📌 0
Maybe I need to look at some head and neck cancer to study both DNA repair and ecDNAs. Come look for me at #AACR25 if you like to chat!
26.04.2025 16:15 — 👍 0 🔁 0 💬 1 📌 0Yes! - we are hiring @yale.edu - links below...
26.04.2025 00:26 — 👍 3 🔁 2 💬 1 📌 0
Highlights of day 1 of #MITS : @steverozen.bsky.social on Aristolochic Acids their effects on carcinogeneis
, @nlbigas.bsky.social on driver mutations in small clones in the bladder. Sir Mike Stratton on signatures stem of the colorectum @mollyprz.bsky.social elegantly solving the etiology of a Sig
A wonderful reminder that my time spent comparing all the ecDNAs in organoids from the @RFitzgerald_lab added new insight to how we can use tumour organoids as a model to study ecDNA.
The future of tumor organoids in precision therapy: Trends in Cancer www.cell.com/trends/cance...
And so it begins. I have been working in genomics / sequencing for more than 30 years but today is a particularly exciting day as I begin training on using the @nanopore MK1D sequencer which we will be using soon for student projects (and other things) at @ucdavis.bsky.social
19.03.2025 14:47 — 👍 96 🔁 8 💬 1 📌 1
The first Singapore Long-Reads Symposium was a success! A massive thanks to the speakers: Keynote Heng Li, Ken Sung @jonathangoeke.bsky.social , @msikic.bsky.social & industrial partners @nanoporetech.com , @pacbio.bsky.social , @awscloud.bsky.social MGI_Technology Next Level Genomics & NovogeneAIT
17.03.2025 02:32 — 👍 8 🔁 2 💬 0 📌 0
I'm happy to announce that my project to use @nanoporetech.com sequencing to study Early Onset Colorectal Cancer has been funded!
25.02.2025 06:09 — 👍 7 🔁 1 💬 0 📌 0
Our 2024 Wrapped! 🧪
- £173m awarded to our Cambridge Institute, @cruk-ci.bsky.social
- £58.7m to train clinician scientists
- 120,000+ people being recruited for the capsule sponge screening trial
- 3 cancer prevention vaccine projects
Read more about our progress this year 👇 cruk.ink/4iLz3ws
SPECIAL ISSUE! This month Genome Research publishes a diverse collection of research and review articles in a special issue highlighting advances in long-read sequencing applications in biology and medicine. Full issue links here: tinyurl.com/Genome-Res-3....
20.11.2024 15:10 — 👍 76 🔁 42 💬 0 📌 5